SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qhb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 GLU A 580
TYR A 578
PHE A 374
 None
 0.54A 1eqbB-1qhbA:
undetectable		 1eqbB-1qhbA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 GLU A 580
TYR A 578
PHE A 374
 None
 0.54A 1eqbA-1qhbA:
undetectable		 1eqbA-1qhbA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 GLU A 580
TYR A 578
PHE A 374
 None
 0.54A 1eqbD-1qhbA:
undetectable		 1eqbD-1qhbA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 GLU A 580
TYR A 578
PHE A 374
 None
 0.55A 1eqbC-1qhbA:
undetectable		 1eqbC-1qhbA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 ILE A 323
LEU A 326
VAL A 330
 None
 0.40A 1mz9B-1qhbA:
undetectable		 1mz9B-1qhbA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 8 ARG A 406
HIS A 478
GLU A 473
ASP A 306
 PO4  A3000 ( 2.7A)
PO4  A3000 (-4.5A)
None
None
 0.88A 1s3zA-1qhbA:
undetectable
1s3zB-1qhbA:
undetectable		 1s3zA-1qhbA:
15.08
1s3zB-1qhbA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 11 ASP A 555
GLY A 544
LEU A 162
TYR A 552
VAL A 550
 None
 1.43A 2uvnB-1qhbA:
undetectable		 2uvnB-1qhbA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 7 ALA A 486
GLY A 484
VAL A 394
LEU A 560
 None
PO4  A3000 ( 3.8A)
None
None
 0.82A 2uyqA-1qhbA:
undetectable		 2uyqA-1qhbA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 8 LEU A 438
LEU A 442
LEU A 167
ALA A 166
 None
 0.76A 2vcvF-1qhbA:
undetectable		 2vcvF-1qhbA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 8 LEU A 438
LEU A 442
LEU A 167
ALA A 166
 None
 0.74A 2vcvP-1qhbA:
0.0		 2vcvP-1qhbA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 9 THR A  58
ILE A  69
GLY A  55
PHE A 428
ILE A  54
 None
 1.32A 2y7wA-1qhbA:
undetectable		 2y7wA-1qhbA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 12 ARG A 213
GLU A 154
GLU A 158
TYR A 552
VAL A 149
 None
 1.36A 3bjmA-1qhbA:
undetectable		 3bjmA-1qhbA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 12 ARG A 213
GLU A 154
GLU A 158
TYR A 552
VAL A 149
 None
 1.41A 3bjmB-1qhbA:
undetectable		 3bjmB-1qhbA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 12 LEU A 391
PRO A 145
GLY A 482
GLY A 484
LEU A 335
 None
None
None
PO4  A3000 ( 3.8A)
None
 1.19A 3e23A-1qhbA:
undetectable		 3e23A-1qhbA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 12 ARG A 213
GLU A 154
GLU A 158
TYR A 552
VAL A 149
 None
 1.38A 3g0bA-1qhbA:
undetectable		 3g0bA-1qhbA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 12 ARG A 213
GLU A 154
GLU A 158
TYR A 552
VAL A 149
 None
 1.36A 3g0bB-1qhbA:
undetectable		 3g0bB-1qhbA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 12 ARG A 213
GLU A 154
GLU A 158
TYR A 552
VAL A 149
 None
 1.37A 3g0bC-1qhbA:
undetectable		 3g0bC-1qhbA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		5 / 12 ARG A 213
GLU A 154
GLU A 158
TYR A 552
VAL A 149
 None
 1.36A 3g0bD-1qhbA:
undetectable		 3g0bD-1qhbA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 7 VAL A 431
VAL A 435
LEU A 438
SER A 439
 None
 0.88A 3hs6B-1qhbA:
undetectable		 3hs6B-1qhbA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 6 GLU A  39
PRO A 407
ARG A 404
GLY A  55
 None
 1.44A 3oxvA-1qhbA:
undetectable		 3oxvA-1qhbA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 6 VAL A 282
VAL A 512
ILE A 241
ARG A 324
 None
 0.95A 3pyyA-1qhbA:
undetectable		 3pyyA-1qhbA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 5 GLY A 482
TYR A 552
TYR A 481
GLU A 158
 None
 1.45A 4ae1B-1qhbA:
undetectable		 4ae1B-1qhbA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 5 HIS A 551
TYR A 552
TYR A 481
GLU A 158
 PO4  A3000 ( 4.0A)
None
None
None
 1.45A 4ae1B-1qhbA:
undetectable		 4ae1B-1qhbA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 8 LEU A 299
PHE A 307
ASP A 458
PHE A 298
 None
 1.09A 4drjB-1qhbA:
undetectable		 4drjB-1qhbA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 5 PHE A 176
PHE A 224
ILE A 323
GLY A 168
 None
 1.04A 4ejjC-1qhbA:
undetectable		 4ejjC-1qhbA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 8 GLY A 226
GLU A 161
LEU A 223
VAL A 218
 None
 0.84A 4fgzA-1qhbA:
undetectable		 4fgzA-1qhbA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 TYR A 481
ARG A 213
SER A 554
 None
 1.00A 4lf7I-1qhbA:
undetectable
4lf7J-1qhbA:
undetectable		 4lf7I-1qhbA:
12.84
4lf7J-1qhbA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 TYR A 481
ARG A 213
SER A 554
 None
 1.00A 4lf8I-1qhbA:
undetectable
4lf8J-1qhbA:
undetectable		 4lf8I-1qhbA:
12.84
4lf8J-1qhbA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 8 GLY A  55
ILE A  54
LEU A 150
GLU A  39
 None
 0.80A 4mwzB-1qhbA:
0.0		 4mwzB-1qhbA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 ASN A 114
ASP A 300
ASP A  65
 None
 0.82A 4obwD-1qhbA:
undetectable		 4obwD-1qhbA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 8 ILE A 543
VAL A 220
LEU A 223
ILE A 185
 None
 0.86A 4r38D-1qhbA:
undetectable		 4r38D-1qhbA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		6 / 12 ARG A  29
VAL A 142
ILE A 570
ALA A 491
GLY A 490
ALA A 390
 None
 1.37A 5kb6B-1qhbA:
undetectable		 5kb6B-1qhbA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 ARG A 109
PHE A 291
LEU A 466
 None
 0.87A 5veuA-1qhbA:
undetectable		 5veuA-1qhbA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 5 HIS A 551
ALA A 486
SER A 483
GLY A 482
 PO4  A3000 ( 4.0A)
None
PO4  A3000 ( 3.0A)
None
 1.24A 5yodD-1qhbA:
undetectable		 5yodD-1qhbA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 ASP A 458
PHE A 310
ARG A 289
 None
 1.16A 5yw0A-1qhbA:
undetectable		 5yw0A-1qhbA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		3 / 3 ARG A 395
ARG A 121
ARG A 406
 None
None
PO4  A3000 ( 2.7A)
 1.05A 6bplA-1qhbA:
undetectable
6bplB-1qhbA:
undetectable		 6bplA-1qhbA:
9.71
6bplB-1qhbA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 1qhb HALOPEROXIDASE
(Corallina
officinalis) 		4 / 4 ILE A 543
LEU A 560
HIS A 485
ALA A 489
 None
None
PO4  A3000 ( 3.9A)
None
 0.96A 6ck2C-1qhbA:
undetectable
6ck2D-1qhbA:
undetectable		 6ck2C-1qhbA:
3.80
6ck2D-1qhbA:
4.08