SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		4 / 5 THR A  20
LEU A  92
GLY A  94
LYS A  97
 SO4  A 248 ( 3.1A)
None
None
SO4  A 251 (-3.5A)
 1.22A 1gtiF-1qhfA:
1.7		 1gtiF-1qhfA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 151
VAL A 154
LEU A 158
 None
 0.50A 1mz9B-1qhfA:
undetectable		 1mz9B-1qhfA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  52
PRO A  49
LEU A  42
ALA A  38
 None
 0.83A 2vcvB-1qhfA:
undetectable		 2vcvB-1qhfA:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  52
PRO A  49
LEU A  42
ALA A  38
 None
 0.94A 2vcvK-1qhfA:
undetectable		 2vcvK-1qhfA:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  52
PRO A  49
LEU A  42
ALA A  38
 None
 0.75A 2vcvP-1qhfA:
undetectable		 2vcvP-1qhfA:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 182
ILE A 155
VAL A 154
 None
 0.41A 3nv6A-1qhfA:
undetectable		 3nv6A-1qhfA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  91
TRP A  13
SER A 127
 None
 0.98A 4lrhB-1qhfA:
undetectable		 4lrhB-1qhfA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  91
TRP A  13
SER A 127
 None
 1.02A 4lrhF-1qhfA:
undetectable		 4lrhF-1qhfA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 197
ARG A  87
ARG A 186
 None
 0.97A 4x5iA-1qhfA:
1.5		 4x5iA-1qhfA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  84
TYR A  53
THR A 175
LEU A 158
 None
 1.09A 5jq7B-1qhfA:
0.0		 5jq7B-1qhfA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)
(Saccharomyces
cerevisiae) 		5 / 12 VAL A   4
LEU A   3
LEU A  84
PRO A  49
LEU A  52
 None
 1.15A 5og9B-1qhfA:
0.0		 5og9B-1qhfA:
21.15