SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qhh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.04A 1cqeA-1qhhA:
undetectable		 1cqeA-1qhhA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.04A 1cqeB-1qhhA:
undetectable		 1cqeB-1qhhA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 8 ILE B 395
PHE B 386
LEU C 516
VAL C 484
 None
 0.84A 1fslA-1qhhB:
undetectable		 1fslA-1qhhB:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 8 SER D 590
PHE D 637
ASN D 639
LEU D 591
 None
 1.07A 1lhvA-1qhhD:
undetectable		 1lhvA-1qhhD:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)		 1qhh PROTEIN (PCRA
(SUBUNIT))
PROTEIN (PCRA
(SUBUNIT))
PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us) 		5 / 11 ALA A  33
GLY A  32
GLU B 283
ASN A  13
GLU D 571
 ATP  A 700 (-3.8A)
None
None
ATP  A 700 (-4.7A)
ATP  A 700 (-3.4A)
 1.29A 1n6cA-1qhhA:
undetectable		 1n6cA-1qhhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 5 TYR B 387
LYS B 385
VAL D 559
ILE B 380
 None
 1.31A 1opjA-1qhhB:
0.0		 1opjA-1qhhB:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.07A 2aylA-1qhhA:
undetectable		 2aylA-1qhhA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.05A 2aylB-1qhhA:
undetectable		 2aylB-1qhhA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 8 ARG B 306
ILE B 256
GLY D 607
ILE D 608
 None
 0.69A 2o4nB-1qhhB:
undetectable		 2o4nB-1qhhB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us) 		5 / 11 LEU D 617
LEU D 577
LEU D 564
ILE B 321
VAL B 299
 None
 1.26A 2qd3A-1qhhD:
undetectable		 2qd3A-1qhhD:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 6 THR C 481
GLU C 485
LYS C 490
ILE B 395
 None
 1.40A 2w98B-1qhhC:
undetectable		 2w98B-1qhhC:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		3 / 3 GLU B 241
ASP B 273
TYR B 233
 None
 0.87A 2yvlB-1qhhB:
undetectable		 2yvlB-1qhhB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 4 VAL A  97
ASP B 191
LEU B 185
ARG A 101
 None
 1.50A 2ziaA-1qhhA:
undetectable		 2ziaA-1qhhA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 5 GLN B 244
PHE B 243
LEU B 210
PHE B 203
 None
 1.30A 3ablC-1qhhB:
undetectable
3ablJ-1qhhB:
0.0		 3ablC-1qhhB:
18.33
3ablJ-1qhhB:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 LEU D 638
ALA D 604
ILE B 300
ILE B 292
PRO D 642
 None
 0.87A 3k4vD-1qhhD:
undetectable		 3k4vD-1qhhD:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 0.99A 3n8wA-1qhhA:
undetectable		 3n8wA-1qhhA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.03A 3n8zA-1qhhA:
undetectable		 3n8zA-1qhhA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.01A 3n8zB-1qhhA:
undetectable		 3n8zB-1qhhA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us) 		5 / 12 TYR B 213
ILE B 196
PHE A  92
THR B 199
ILE B 200
 None
 1.28A 3ndiA-1qhhB:
undetectable		 3ndiA-1qhhB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 LEU D 638
ALA D 604
ILE B 300
ILE B 292
PRO D 642
 None
 0.98A 3nduB-1qhhD:
undetectable		 3nduB-1qhhD:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 LEU D 638
ALA D 604
ILE B 300
ILE B 292
PRO D 642
 None
 0.91A 3nduD-1qhhD:
undetectable		 3nduD-1qhhD:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 10 ALA D 567
ILE B 321
LEU D 577
ILE B 300
ILE B 311
 None
 0.97A 3prsA-1qhhD:
undetectable		 3prsA-1qhhD:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  98
ARG A  73
ASP A  86
 None
 0.82A 3wipG-1qhhA:
undetectable
3wipH-1qhhA:
undetectable		 3wipG-1qhhA:
20.42
3wipH-1qhhA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 7 LEU C 512
ARG C 508
GLY C 492
TYR C 493
 None
 0.96A 4cp3A-1qhhC:
undetectable
4cp3B-1qhhC:
undetectable		 4cp3A-1qhhC:
20.14
4cp3B-1qhhC:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  41
ALA A  61
ILE A  89
LYS A  37
 None
None
None
ATP  A 700 ( 4.1A)
 1.27A 4eixA-1qhhA:
undetectable		 4eixA-1qhhA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qhh PROTEIN (PCRA
(SUBUNIT))
PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us) 		5 / 12 LEU D 617
LEU D 577
LEU D 564
ILE B 321
VAL B 299
 None
 1.18A 4f4dB-1qhhD:
undetectable		 4f4dB-1qhhD:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 8 ALA A 150
LEU A 156
THR A 147
SER B 174
 None
 0.93A 4ikkA-1qhhA:
undetectable
4ikkB-1qhhA:
undetectable		 4ikkA-1qhhA:
21.89
4ikkB-1qhhA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 LEU B 185
LEU B 195
PHE A 113
GLN B 201
ASP A 105
 None
 1.44A 4j7xJ-1qhhB:
undetectable		 4j7xJ-1qhhB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 111
ASP A 103
ASP A 105
ARG A 106
 None
 1.20A 4kcnA-1qhhA:
undetectable		 4kcnA-1qhhA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 111
ASP A 103
ASP A 105
ARG A 106
 None
 1.21A 4kcnB-1qhhA:
undetectable		 4kcnB-1qhhA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qhh PROTEIN (PCRA
(SUBUNIT))
PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us) 		5 / 8 LEU D 617
LEU D 577
LEU D 564
ILE B 321
VAL B 299
 None
 1.27A 4klaA-1qhhD:
undetectable		 4klaA-1qhhD:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 4 LEU C 531
SER C 479
LEU C 474
LEU B 399
 None
 1.07A 4n09A-1qhhC:
undetectable		 4n09A-1qhhC:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 9 LEU C 497
GLU B 391
ASN C 511
ALA B 362
GLU C 510
 None
 1.31A 4omwD-1qhhC:
undetectable		 4omwD-1qhhC:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 6 THR C 481
GLU C 523
THR C 519
THR D 624
 None
 1.04A 4pgfA-1qhhC:
undetectable		 4pgfA-1qhhC:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 6 ALA A  33
GLY D 607
ILE B 311
VAL B 299
 ATP  A 700 (-3.8A)
None
None
None
 0.83A 4r21A-1qhhA:
undetectable		 4r21A-1qhhA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 ALA B 248
ILE B 280
LEU B 282
GLY A  36
GLN A  16
 None
None
None
ATP  A 700 (-3.4A)
ATP  A 700 (-2.8A)
 0.94A 4r3aB-1qhhB:
undetectable		 4r3aB-1qhhB:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 9 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.07A 4rs0A-1qhhA:
undetectable		 4rs0A-1qhhA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		3 / 3 GLU B 301
ARG B 306
GLN B 294
 None
 0.86A 4rtbA-1qhhB:
undetectable		 4rtbA-1qhhB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 4 LEU C 441
LEU C 445
GLY C 446
GLU C 447
 None
 1.06A 5hhjA-1qhhC:
undetectable		 5hhjA-1qhhC:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 ASP D 632
GLU D 582
LEU D 577
LEU D 564
THR D 563
 None
 0.99A 5hnwB-1qhhD:
undetectable		 5hnwB-1qhhD:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 ASP D 632
GLU D 582
LEU D 577
LEU D 564
THR D 563
 None
 0.95A 5hnxB-1qhhD:
undetectable		 5hnxB-1qhhD:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 ASP D 632
GLU D 582
LEU D 577
LEU D 564
THR D 563
 None
 0.98A 5hnyB-1qhhD:
undetectable		 5hnyB-1qhhD:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  40
LEU A  41
GLY B 250
ALA A  31
LEU B 282
 None
 1.16A 5ikrA-1qhhA:
undetectable		 5ikrA-1qhhA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		6 / 12 VAL A  40
LEU A  41
ALA A  68
GLY B 250
ALA A  31
LEU B 282
 None
 1.10A 5kirA-1qhhA:
undetectable		 5kirA-1qhhA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 6 LEU B 235
PHE B 203
ASP B 204
HIS B 211
 None
 1.03A 5om3A-1qhhB:
0.0
5om3B-1qhhB:
undetectable		 5om3A-1qhhB:
14.71
5om3B-1qhhB:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		3 / 3 ARG B 413
ILE B 414
SER B 410
 None
 0.83A 5zw2A-1qhhB:
undetectable		 5zw2A-1qhhB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qhh PROTEIN (PCRA
(SUBUNIT))
(Geobacillus
stearothermophil
us) 		4 / 6 GLN B 244
PHE B 243
LEU B 210
PHE B 203
 None
 1.31A 6nmpC-1qhhB:
undetectable
6nmpJ-1qhhB:
0.0		 6nmpC-1qhhB:
18.33
6nmpJ-1qhhB:
13.69