SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qhl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 9 LEU A  51
VAL A 102
VAL A 104
GLY A 103
LEU A 221
 None
 1.37A 1lwfA-1qhlA:
undetectable		 1lwfA-1qhlA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 9 LEU A 188
ILE A 184
PHE A 197
LEU A  51
ILE A  52
 None
 1.27A 2f7aA-1qhlA:
undetectable		 2f7aA-1qhlA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 12 LEU A  90
ALA A  46
ALA A  50
THR A  22
LEU A  28
 None
 1.18A 2japA-1qhlA:
undetectable		 2japA-1qhlA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 12 LEU A  90
ALA A  46
ALA A  50
THR A  22
LEU A  28
 None
 1.19A 2japB-1qhlA:
undetectable		 2japB-1qhlA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 12 LEU A  90
ALA A  46
ALA A  50
THR A  22
LEU A  28
 None
 1.19A 2japC-1qhlA:
undetectable		 2japC-1qhlA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 12 LEU A  90
ALA A  46
ALA A  50
THR A  22
LEU A  28
 None
 1.17A 2japD-1qhlA:
undetectable		 2japD-1qhlA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 12 LEU A 221
LEU A  90
ILE A  52
TYR A 198
PHE A  47
 None
 1.24A 2weyA-1qhlA:
undetectable		 2weyA-1qhlA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 12 ARG A   8
PHE A   7
GLY A   5
ILE A 183
ASN A  94
 None
 1.05A 2zzmA-1qhlA:
0.0		 2zzmA-1qhlA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 12 ARG A   8
PHE A   7
GLY A   5
ILE A 183
ASN A  94
 None
 0.99A 2zznA-1qhlA:
undetectable		 2zznA-1qhlA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		3 / 3 GLN A  98
THR A  92
ASN A  94
 None
 0.90A 3v4tE-1qhlA:
0.0		 3v4tE-1qhlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 11 ARG A   8
PHE A   7
GLY A   5
ILE A 183
ASN A  94
 None
 1.15A 5hjiA-1qhlA:
undetectable		 5hjiA-1qhlA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		3 / 3 ARG A 146
PRO A 149
ASN A 151
 None
 1.03A 5jwaA-1qhlA:
undetectable
5jwaH-1qhlA:
undetectable		 5jwaA-1qhlA:
17.57
5jwaH-1qhlA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 9 LEU A  90
THR A  92
GLY A 182
ILE A 184
PHE A  47
 None
 1.21A 6ebpA-1qhlA:
undetectable		 6ebpA-1qhlA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 10 LEU A  90
THR A  92
GLY A 182
ILE A 184
PHE A  47
 None
 1.20A 6ebpB-1qhlA:
undetectable		 6ebpB-1qhlA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1qhl PROTEIN (CELL
DIVISION PROTEIN
MUKB)
(Escherichia
coli) 		5 / 10 LEU A  90
THR A  92
GLY A 182
ILE A 184
PHE A  47
 None
 1.16A 6ebpC-1qhlA:
undetectable		 6ebpC-1qhlA:
14.54