SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		5 / 12 ILE A 534
LEU A 536
ILE A 516
MET A 553
PHE A 555
 None
 1.07A 2ygnA-1qhvA:
0.0		 2ygnA-1qhvA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 6 PHE A 497
ALA A 580
LEU A 536
PRO A 499
 None
 1.00A 3bgdA-1qhvA:
undetectable		 3bgdA-1qhvA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 7 LEU A 445
ALA A 440
ILE A 457
THR A 449
 None
 0.66A 3spkB-1qhvA:
undetectable		 3spkB-1qhvA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 7 THR A 435
ALA A 437
LEU A 439
THR A 422
 None
 0.83A 4d7bA-1qhvA:
undetectable		 4d7bA-1qhvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 5 LYS A 528
PRO A 529
GLU A 567
TYR A 564
 None
 1.05A 4w5tA-1qhvA:
undetectable		 4w5tA-1qhvA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 6 LYS A 528
PRO A 529
GLU A 567
TYR A 564
 None
 1.14A 4z4cA-1qhvA:
undetectable		 4z4cA-1qhvA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 7 LYS A 528
PRO A 529
GLU A 567
TYR A 564
 None
 0.96A 4z4fA-1qhvA:
undetectable		 4z4fA-1qhvA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 6 LYS A 528
PRO A 529
GLU A 567
TYR A 564
 None
 1.07A 4z4gA-1qhvA:
undetectable		 4z4gA-1qhvA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 7 THR A 435
ALA A 437
LEU A 439
THR A 422
 None
 0.80A 5bojB-1qhvA:
undetectable		 5bojB-1qhvA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		5 / 12 LEU A 423
LEU A 425
LEU A 473
ALA A 494
MET A 498
 None
 1.05A 5og9B-1qhvA:
undetectable		 5og9B-1qhvA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 7 LYS A 528
PRO A 529
GLU A 567
TYR A 564
 None
 0.96A 5t7bA-1qhvA:
undetectable		 5t7bA-1qhvA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1qhv PROTEIN (ADENOVIRUS
FIBRE)
(Human
mastadenovirus
C) 		4 / 5 ASN A 514
VAL A 432
LEU A 425
SER A 552
 None
 1.30A 6a7pA-1qhvA:
undetectable		 6a7pA-1qhvA:
15.79