SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 ASP A 490
LEU A 134
PHE A 489
ALA A 348
GLU A  47
 None
 1.33A 1a4lB-1qi9A:
undetectable		 1a4lB-1qi9A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 GLY A 201
PHE A 478
VAL A 474
LEU A 495
ALA A 179
 None
 1.47A 1e3vA-1qi9A:
0.0		 1e3vA-1qi9A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 8 PHE A 324
TYR A 323
ILE A 320
LEU A 289
 None
 0.78A 1fslA-1qi9A:
undetectable		 1fslA-1qi9A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 11 ASN A 475
SER A 416
GLY A 491
PHE A 478
GLY A 494
 None
VO4  A 600 (-2.8A)
None
None
None
 1.37A 1ho5A-1qi9A:
undetectable		 1ho5A-1qi9A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		3 / 3 ILE A 469
LEU A 472
VAL A 476
 None
 0.49A 1mz9B-1qi9A:
undetectable		 1mz9B-1qi9A:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 ASN A 298
ASN A 303
ILE A 320
GLY A 319
 None
 1.09A 1oniD-1qi9A:
undetectable
1oniF-1qi9A:
undetectable		 1oniD-1qi9A:
16.44
1oniF-1qi9A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 5 PRO A  98
PRO A 252
ILE A 246
GLY A 250
 None
 1.05A 2jkjD-1qi9A:
undetectable		 2jkjD-1qi9A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 5 PRO A  98
PRO A 252
ILE A 246
GLY A 250
 None
 1.05A 2jkjF-1qi9A:
undetectable		 2jkjF-1qi9A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 SER A 413
TYR A 487
VAL A 141
ASP A 490
 None
 1.35A 2x45A-1qi9A:
undetectable		 2x45A-1qi9A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		3 / 3 ARG A 286
GLU A 228
SER A 215
 None
 0.83A 2xkkA-1qi9A:
undetectable
2xkkC-1qi9A:
undetectable		 2xkkA-1qi9A:
21.44
2xkkC-1qi9A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 LEU A  74
ILE A  78
PRO A 105
VAL A 141
 None
 1.18A 2ygoA-1qi9A:
0.0		 2ygoA-1qi9A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 8 GLY A 417
ILE A 492
PHE A 195
PHE A 207
 VO4  A 600 (-3.8A)
None
None
None
 0.91A 3ko0K-1qi9A:
0.0
3ko0S-1qi9A:
0.0		 3ko0K-1qi9A:
11.13
3ko0S-1qi9A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 ILE A 386
VAL A 383
ARG A 382
LEU A 379
 None
 0.64A 3kp6A-1qi9A:
0.5
3kp6B-1qi9A:
0.3		 3kp6A-1qi9A:
15.23
3kp6B-1qi9A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 LEU A 495
GLY A 438
ALA A 426
LEU A 291
ILE A 433
 None
 0.89A 3ku1A-1qi9A:
undetectable		 3ku1A-1qi9A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 LEU A 495
GLY A 438
ALA A 426
LEU A 291
ILE A 433
 None
 0.88A 3ku1H-1qi9A:
undetectable		 3ku1H-1qi9A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 10 GLY A 254
ALA A 253
ASN A 245
GLY A 407
ILE A 404
 None
 0.93A 3lzvA-1qi9A:
undetectable		 3lzvA-1qi9A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 GLN A  65
GLY A  64
LEU A  58
SER A  57
ALA A 352
 None
 1.19A 3sxjA-1qi9A:
undetectable		 3sxjA-1qi9A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 GLN A  65
GLY A  64
LEU A  58
SER A  57
ALA A 352
 None
 1.19A 3sxjB-1qi9A:
undetectable		 3sxjB-1qi9A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		3 / 3 ARG A 504
PRO A 545
PHE A 537
 None
 0.94A 3thrC-1qi9A:
undetectable		 3thrC-1qi9A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 8 LEU A 435
GLY A 439
THR A 464
VAL A 200
 None
 0.84A 4c9nA-1qi9A:
undetectable		 4c9nA-1qi9A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 LEU A 177
ASP A 178
ALA A 419
SER A 413
LEU A 129
 None
 1.14A 4iarA-1qi9A:
undetectable		 4iarA-1qi9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 5 LYS A 471
LEU A 472
GLU A 468
LEU A 211
 None
 1.24A 4k4yA-1qi9A:
0.0		 4k4yA-1qi9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		3 / 3 LEU A 258
ARG A 269
MET A 144
 None
 0.52A 4m11C-1qi9A:
0.2		 4m11C-1qi9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 ILE A 246
GLY A 100
VAL A  91
HIS A  60
 None
 0.89A 4oltA-1qi9A:
undetectable		 4oltA-1qi9A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 8 PHE A 524
PHE A 199
PHE A 478
GLY A 494
ILE A 123
 None
 1.32A 4qoiA-1qi9A:
0.0
4qoiB-1qi9A:
0.0		 4qoiA-1qi9A:
17.72
4qoiB-1qi9A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 7 GLY A 100
THR A 410
VAL A  91
HIS A  60
 None
 0.91A 4qwpB-1qi9A:
0.9		 4qwpB-1qi9A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 7 GLU A 351
LEU A 353
LEU A 138
LEU A 134
 None
 0.68A 4wg0B-1qi9A:
undetectable
4wg0C-1qi9A:
undetectable		 4wg0B-1qi9A:
2.43
4wg0C-1qi9A:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 7 LEU A 138
LEU A 134
GLU A 351
LEU A 353
 None
 0.65A 4wg0L-1qi9A:
undetectable
4wg0M-1qi9A:
undetectable		 4wg0L-1qi9A:
2.43
4wg0M-1qi9A:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		3 / 3 VAL A 213
PHE A 152
ARG A 196
 None
 0.81A 4xr4B-1qi9A:
undetectable		 4xr4B-1qi9A:
25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 7 GLY A 434
GLY A 304
TYR A 323
ALA A 431
 None
 0.99A 5e26A-1qi9A:
undetectable
5e26B-1qi9A:
undetectable		 5e26A-1qi9A:
19.61
5e26B-1qi9A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 4 ASN A 470
ILE A 501
TYR A 549
PHE A 519
 None
 1.47A 5igvA-1qi9A:
0.7		 5igvA-1qi9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 SER A 416
GLY A 423
ASN A 422
ILE A 492
 VO4  A 600 (-2.8A)
None
None
None
 1.11A 5j4nA-1qi9A:
undetectable		 5j4nA-1qi9A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		3 / 3 GLN A 227
THR A 229
ASP A 270
 None
 0.88A 5k9dA-1qi9A:
undetectable		 5k9dA-1qi9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		6 / 12 GLU A 499
ILE A 501
GLU A 509
ALA A 333
PHE A 524
ALA A 424
 None
 1.31A 5n5dB-1qi9A:
undetectable		 5n5dB-1qi9A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		6 / 12 LEU A 429
GLU A 499
ILE A 501
ALA A 333
PHE A 524
ALA A 424
 None
 1.31A 5n5dB-1qi9A:
undetectable		 5n5dB-1qi9A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		3 / 3 ARG A 196
PRO A 206
TYR A 155
 None
 1.06A 5tzoB-1qi9A:
undetectable		 5tzoB-1qi9A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		5 / 12 ALA A 145
ALA A 147
THR A 161
LEU A 194
LEU A 168
 None
 1.12A 6aybA-1qi9A:
undetectable		 6aybA-1qi9A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 5 LEU A 380
LEU A 146
THR A 397
ARG A 349
 None
None
None
VO4  A 600 (-2.7A)
 1.05A 6ew0F-1qi9A:
undetectable		 6ew0F-1qi9A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 LEU A 380
LEU A 146
THR A 397
ARG A 349
 None
None
None
VO4  A 600 (-2.7A)
 1.05A 6ew0G-1qi9A:
undetectable		 6ew0G-1qi9A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)
(Ascophyllum
nodosum) 		4 / 6 ALA A 107
GLY A 417
THR A 420
ILE A 501
 None
VO4  A 600 (-3.8A)
None
None
 0.83A 6f8cA-1qi9A:
0.2		 6f8cA-1qi9A:
12.23