SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 5 HIS A 166
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.27A 1os2A-1qibA:
27.8		 1os2A-1qibA:
58.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.30A 1os2D-1qibA:
27.8		 1os2D-1qibA:
58.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 12 ALA A 167
GLY A 176
GLY A 175
ASP A 181
GLY A 147
 None
CA  A 504 ( 4.6A)
CA  A 504 (-4.6A)
CA  A 503 (-3.6A)
None
 1.05A 1sqfA-1qibA:
undetectable		 1sqfA-1qibA:
17.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.26A 1uttA-1qibA:
28.1		 1uttA-1qibA:
59.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.28A 1utzA-1qibA:
27.8		 1utzA-1qibA:
59.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.30A 1utzB-1qibA:
27.8		 1utzB-1qibA:
59.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 6 HIS A 166
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.31A 1y93A-1qibA:
26.8		 1y93A-1qibA:
59.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 11 LEU A 209
THR A 128
PRO A 129
ASN A  95
LEU A 218
 None
 1.33A 2ft9A-1qibA:
undetectable		 2ft9A-1qibA:
20.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.27A 2hu6A-1qibA:
27.8		 2hu6A-1qibA:
59.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 9 LEU A 164
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 None
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.29A 2jihA-1qibA:
9.9		 2jihA-1qibA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 8 LEU A 164
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 None
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.33A 2jihB-1qibA:
10.1		 2jihB-1qibA:
18.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		6 / 6 LEU A 163
HIS A 166
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 None
ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.67A 2ow9A-1qibA:
27.6		 2ow9A-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.31A 2ow9B-1qibA:
27.8		 2ow9B-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.32A 2ozrC-1qibA:
28.0		 2ozrC-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.30A 2ozrD-1qibA:
28.2		 2ozrD-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.22A 2ozrE-1qibA:
27.7		 2ozrE-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		3 / 3 HIS A 201
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.19A 2ozrF-1qibA:
27.7		 2ozrF-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		3 / 3 HIS A 166
GLU A 202
HIS A 205
 ZN  A 502 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
 0.55A 3ba0A-1qibA:
25.8		 3ba0A-1qibA:
38.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 9 HIS A 201
GLU A 202
HIS A 205
HIS A 211
ILE A 222
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
None
 0.76A 3hy7A-1qibA:
10.4		 3hy7A-1qibA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 9 LEU A 164
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 None
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.35A 3hy7A-1qibA:
10.4		 3hy7A-1qibA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		6 / 9 LEU A 164
HIS A 201
GLU A 202
HIS A 205
HIS A 211
ILE A 222
 None
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
None
 0.54A 3hy7B-1qibA:
10.2		 3hy7B-1qibA:
19.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 5 LEU A 163
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 None
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.64A 3kecA-1qibA:
28.0		 3kecA-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 5 HIS A 166
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.35A 3likA-1qibA:
27.1		 3likA-1qibA:
59.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.31A 3lilA-1qibA:
27.7		 3lilA-1qibA:
59.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 5 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.30A 3ljgA-1qibA:
27.7		 3ljgA-1qibA:
59.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 5 HIS A 166
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.35A 3lkaA-1qibA:
27.6		 3lkaA-1qibA:
59.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 5 PHE A 180
PHE A 203
ALA A 200
LEU A 195
 None
 1.12A 3t3zC-1qibA:
undetectable		 3t3zC-1qibA:
15.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 6 HIS A 166
HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.41A 4a7bA-1qibA:
27.7		 4a7bA-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 6 LEU A 163
HIS A 166
HIS A 201
HIS A 205
HIS A 211
 None
ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.75A 4a7bA-1qibA:
27.7		 4a7bA-1qibA:
65.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		5 / 5 LEU A 163
HIS A 166
HIS A 201
GLU A 202
HIS A 205
 None
ZN  A 502 (-3.5A)
ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
 0.65A 4a7bB-1qibA:
27.7		 4a7bB-1qibA:
65.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 5 GLN A 243
THR A 128
LEU A 218
LEU A 234
 None
 1.06A 4lvcB-1qibA:
undetectable		 4lvcB-1qibA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 GLN A 243
THR A 128
LEU A 218
LEU A 234
 None
 1.06A 5m5kB-1qibA:
undetectable		 5m5kB-1qibA:
16.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 4 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.30A 5n5jA-1qibA:
27.8		 5n5jA-1qibA:
59.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 5 HIS A 201
GLU A 202
HIS A 205
HIS A 211
 ZN  A 501 (-3.5A)
ZN  A 501 ( 4.5A)
ZN  A 501 (-3.5A)
ZN  A 501 (-3.5A)
 0.32A 5n5kA-1qibA:
27.3		 5n5kA-1qibA:
58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		4 / 5 HIS A 166
HIS A 151
HIS A 179
PHE A 168
 ZN  A 502 (-3.5A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.4A)
None
 1.28A 5zrdC-1qibA:
undetectable		 5zrdC-1qibA:
14.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 1qib 72 KDA TYPE IV
COLLAGENASE
(Homo
sapiens) 		3 / 3 TYR A 155
HIS A 166
PHE A 168
 None
ZN  A 502 (-3.5A)
None
 0.14A 6esmA-1qibA:
27.7		 6esmA-1qibA:
58.75