SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qil'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		5 / 9 LEU A  10
LEU A   9
ILE A   6
LEU A 143
ARG A 145
 None
 1.23A 2f7aA-1qilA:
undetectable		 2f7aA-1qilA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 6 THR A 128
THR A  89
ASN A  37
ASP A  39
 None
 1.13A 2okcA-1qilA:
undetectable		 2okcA-1qilA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 8 ILE A 126
ASP A 130
ARG A 134
TRP A 154
 None
 1.05A 2v57A-1qilA:
undetectable		 2v57A-1qilA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 8 ILE A 126
ASP A 130
ARG A 134
TRP A 154
 None
 1.05A 2v57C-1qilA:
undetectable		 2v57C-1qilA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 6 THR A  19
ASN A  65
GLY A  87
ILE A  35
 None
 1.04A 3w9tF-1qilA:
undetectable		 3w9tF-1qilA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		5 / 12 SER A 127
PHE A 131
VAL A 104
LEU A 102
PRO A 101
 None
 1.18A 5ergB-1qilA:
undetectable		 5ergB-1qilA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 6 ILE A  45
VAL A  62
VAL A  88
SER A  23
 None
 0.94A 5jwaH-1qilA:
undetectable		 5jwaH-1qilA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 1qil TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 5 PHE A  47
SER A  32
ASN A  37
GLN A  84
 None
 1.39A 5kpcA-1qilA:
0.0		 5kpcA-1qilA:
18.23