SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qjc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 8 LEU A 113
ARG A 107
VAL A 116
ALA A 103
 None
 0.92A 1fiqC-1qjcA:
undetectable		 1fiqC-1qjcA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 TYR A   7
LEU A  34
ALA A  55
LEU A  54
ARG A  51
 None
 1.25A 1mx8A-1qjcA:
undetectable		 1mx8A-1qjcA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 VAL A  32
ASN A  64
VAL A  22
ILE A  87
 None
 1.05A 1z2bC-1qjcA:
undetectable		 1z2bC-1qjcA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A  54
ALA A  58
ALA A 153
PHE A  11
PHE A  46
 None
 1.04A 2ejtA-1qjcA:
4.0		 2ejtA-1qjcA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 7 LEU A 109
PRO A   8
GLU A  99
ARG A  88
 None
 0.96A 2jn3A-1qjcA:
undetectable		 2jn3A-1qjcA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 8 LEU A 113
ARG A 107
VAL A 116
ALA A 103
 None
 1.00A 3ax9A-1qjcA:
undetectable		 3ax9A-1qjcA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 11 ILE A  14
ALA A  58
VAL A  67
VAL A  65
GLY A  63
 None
 0.93A 3kw4A-1qjcA:
undetectable		 3kw4A-1qjcA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 ILE A  21
PRO A 120
SER A 128
GLY A  17
 None
None
SO4  A1161 (-4.8A)
None
 1.10A 3tkdB-1qjcA:
undetectable		 3tkdB-1qjcA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 ILE A  21
PRO A 120
SER A 128
GLY A  17
 None
None
SO4  A1161 (-4.8A)
None
 1.11A 3tkdA-1qjcA:
undetectable		 3tkdA-1qjcA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_C_ACTC510_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 ARG A  51
THR A  10
ASP A  12
LYS A  42
 None
 0.97A 3v5vC-1qjcA:
0.0
3v5vD-1qjcA:
0.0		 3v5vC-1qjcA:
18.40
3v5vD-1qjcA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_B_ACTB502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 LYS A  42
ARG A  51
THR A  10
ASP A  12
 None
 0.94A 4e7cA-1qjcA:
0.0
4e7cB-1qjcA:
0.0		 4e7cA-1qjcA:
18.40
4e7cB-1qjcA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 LEU A 146
ASN A  16
MET A  45
LEU A  54
 None
 1.08A 4okxA-1qjcA:
undetectable		 4okxA-1qjcA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 GLU A  50
ASP A  12
PRO A  13
 None
 0.80A 6berA-1qjcA:
undetectable		 6berA-1qjcA:
9.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 5 GLY A   9
THR A  10
HIS A  18
SER A 128
SER A 129
 None
None
SO4  A1161 (-4.2A)
SO4  A1161 (-4.8A)
SO4  A1161 (-3.0A)
 0.38A 6jmjA-1qjcA:
24.7		 6jmjA-1qjcA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		6 / 7 GLY A   9
THR A  10
PHE A  11
HIS A  18
SER A 128
SER A 129
 None
None
None
SO4  A1161 (-4.2A)
SO4  A1161 (-4.8A)
SO4  A1161 (-3.0A)
 0.39A 6jnhA-1qjcA:
24.8		 6jnhA-1qjcA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 7 GLY A   9
THR A  10
PHE A  11
SER A 130
SER A 129
 None
None
None
None
SO4  A1161 (-3.0A)
 1.48A 6jnhA-1qjcA:
24.8		 6jnhA-1qjcA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 6 GLY A   9
THR A  10
HIS A  18
SER A 128
SER A 129
 None
None
SO4  A1161 (-4.2A)
SO4  A1161 (-4.8A)
SO4  A1161 (-3.0A)
 0.44A 6jogA-1qjcA:
24.6		 6jogA-1qjcA:
60.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 7 HIS A  18
THR A  15
ARG A  24
ASP A  20
 SO4  A1161 (-4.2A)
SO4  A1161 ( 4.8A)
SO4  A1160 ( 4.6A)
None
 1.15A 6mn4E-1qjcA:
undetectable		 6mn4E-1qjcA:
19.25