SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qjp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1qjp OUTER MEMBRANE
PROTEIN A
(Escherichia
coli) 		5 / 8 GLY A  36
ALA A  37
ASP A  56
GLY A 165
LEU A 164
 None
C8E  A1176 (-3.7A)
None
None
C8E  A1173 ( 4.3A)
 1.25A 3em6A-1qjpA:
undetectable		 3em6A-1qjpA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1qjp OUTER MEMBRANE
PROTEIN A
(Escherichia
coli) 		3 / 3 ALA A 136
ARG A 138
LYS A  12
 None
 1.07A 3kp5B-1qjpA:
undetectable		 3kp5B-1qjpA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 1qjp OUTER MEMBRANE
PROTEIN A
(Escherichia
coli) 		4 / 5 SER A 167
ARG A 138
GLU A  52
PHE A  40
 None
 1.31A 4r82A-1qjpA:
undetectable
4r82B-1qjpA:
undetectable		 4r82A-1qjpA:
28.17
4r82B-1qjpA:
28.17