SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qjs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 PHE A 113
PHE A  78
TYR A  86
GLY A 135
LEU A 149
 None
 1.09A 1fe2A-1qjsA:
0.0		 1fe2A-1qjsA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		4 / 8 LEU A 380
SER A 241
GLN A 273
THR A 304
 PO4  A 501 (-3.5A)
None
None
None
 1.09A 1ig3A-1qjsA:
undetectable
1ig3B-1qjsA:
undetectable		 1ig3A-1qjsA:
20.57
1ig3B-1qjsA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 PHE A 113
PHE A  78
TYR A  86
GLY A 135
LEU A 149
 None
 1.10A 1igxA-1qjsA:
undetectable		 1igxA-1qjsA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ASP A 259
ASP A 242
LYS A 384
 None
 0.98A 1lqtB-1qjsA:
undetectable		 1lqtB-1qjsA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ASP A 259
ASP A 242
LYS A 384
 None
 1.00A 1lquB-1qjsA:
undetectable		 1lquB-1qjsA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		4 / 8 VAL A 412
HIS A 346
LEU A 353
TRP A 355
 None
 1.11A 1pk2A-1qjsA:
undetectable		 1pk2A-1qjsA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 GLY A 180
SER A 167
VAL A 201
SER A  28
LEU A 206
 None
CL  A 511 (-4.9A)
None
None
None
 1.06A 1ya4C-1qjsA:
undetectable		 1ya4C-1qjsA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		4 / 4 GLY A 224
SER A 267
VAL A 249
LEU A 234
 None
 0.83A 1yajB-1qjsA:
undetectable		 1yajB-1qjsA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 HIS A 244
GLU A 130
HIS A 127
 None
 0.88A 3ba0A-1qjsA:
20.5		 3ba0A-1qjsA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		4 / 7 TRP A 145
PHE A 146
ILE A 136
TRP A 147
 None
 1.47A 3ej8A-1qjsA:
0.0
3ej8B-1qjsA:
0.0		 3ej8A-1qjsA:
19.38
3ej8B-1qjsA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ARG A 174
ARG A 257
TRP A 268
 HEM  A 500 (-4.2A)
None
None
 1.42A 4b7nA-1qjsA:
3.6		 4b7nA-1qjsA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ARG A 174
ARG A 257
TRP A 268
 HEM  A 500 (-4.2A)
None
None
 1.43A 4cpzC-1qjsA:
2.2		 4cpzC-1qjsA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ARG A 174
ARG A 257
TRP A 268
 HEM  A 500 (-4.2A)
None
None
 1.48A 4cpzE-1qjsA:
4.9		 4cpzE-1qjsA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ARG A 174
ARG A 257
TRP A 268
 HEM  A 500 (-4.2A)
None
None
 1.38A 4cpzF-1qjsA:
2.9		 4cpzF-1qjsA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ARG A 174
ARG A 257
TRP A 268
 HEM  A 500 (-4.2A)
None
None
 1.37A 4cpzG-1qjsA:
2.2		 4cpzG-1qjsA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ARG A 174
ARG A 257
TRP A 268
 HEM  A 500 (-4.2A)
None
None
 1.36A 4cpzH-1qjsA:
2.1		 4cpzH-1qjsA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 ILE A 347
ALA A 336
ALA A 335
ALA A 284
ILE A 328
 None
CL  A 521 (-4.5A)
CL  A 521 (-4.1A)
NA  A 522 (-4.8A)
None
 0.92A 4nqaH-1qjsA:
undetectable		 4nqaH-1qjsA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		4 / 5 PHE A 138
LEU A 149
GLY A 152
ILE A 116
 None
 1.01A 5ik1A-1qjsA:
undetectable		 5ik1A-1qjsA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 LYS A  48
ASP A  49
ARG A  60
 None
 0.92A 5jwaA-1qjsA:
undetectable
5jwaH-1qjsA:
undetectable		 5jwaA-1qjsA:
19.89
5jwaH-1qjsA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		3 / 3 ARG A 262
PHE A  78
LEU A  45
 None
 0.76A 5veuA-1qjsA:
undetectable		 5veuA-1qjsA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1qjs HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 PHE A 113
ILE A  88
ALA A  77
THR A  37
GLY A  81
 None
None
NA  A 513 ( 4.9A)
None
None
 1.07A 5veuB-1qjsA:
undetectable		 5veuB-1qjsA:
22.10