SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ql0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 1ql0 NUCLEASE
(Serratia
marcescens) 		5 / 12 MET A 241
PHE A 188
ALA A 186
ILE A 218
THR A 144
 None
 1.21A 2bjfA-1ql0A:
1.4		 2bjfA-1ql0A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1ql0 NUCLEASE
(Serratia
marcescens) 		3 / 3 TRP A 123
GLN A 192
TRP A  41
 None
 1.12A 2vqyA-1ql0A:
undetectable		 2vqyA-1ql0A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1ql0 NUCLEASE
(Serratia
marcescens) 		5 / 12 ALA A  39
ASP A  62
PRO A  63
ALA A  64
ILE A 111
 None
 1.07A 3jb1A-1ql0A:
undetectable		 3jb1A-1ql0A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1ql0 NUCLEASE
(Serratia
marcescens) 		5 / 12 GLU A 127
GLY A 121
PHE A 200
ASP A 199
ALA A 198
 None
 1.23A 3nmuA-1ql0A:
0.0
3nmuF-1ql0A:
undetectable		 3nmuA-1ql0A:
20.05
3nmuF-1ql0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 1ql0 NUCLEASE
(Serratia
marcescens) 		4 / 7 HIS A 184
LEU A 240
GLY A 235
ALA A 186
 None
 0.99A 3tehB-1ql0A:
undetectable		 3tehB-1ql0A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1ql0 NUCLEASE
(Serratia
marcescens) 		5 / 12 PHE A  38
SER A  18
ILE A 111
ASN A 110
PRO A 167
 None
 1.26A 4rtpA-1ql0A:
undetectable		 4rtpA-1ql0A:
19.61