SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ql4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UKB_A_BEZA1300_0 (2-HYDROXY-6-OXO-7-ME THYLOCTA-2,4-DIENOAT E HYDROLASE)	1ql4	CYTOCHROME C552 (Paracoccus denitrificans)	5 / 11	GLY A 55 ALA A 61 LEU A 62 VAL A 73 VAL A 72	None	1.13A	1ukbA-1ql4A: undetectable	1ukbA-1ql4A: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UKB_A_BEZA1300_0 (2-HYDROXY-6-OXO-7-ME THYLOCTA-2,4-DIENOAT E HYDROLASE)	1ql4	CYTOCHROME C552 (Paracoccus denitrificans)	5 / 11	GLY A 55 ALA A 61 VAL A 73 VAL A 72 HIS A 53	None	1.12A	1ukbA-1ql4A: undetectable	1ukbA-1ql4A: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VMY_B_GLYB502_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1ql4	CYTOCHROME C552 (Paracoccus denitrificans)	4 / 8	TYR A 46 HIS A 18 HIS A 29 ARG A 36	HEC A 101 (-4.5A) HEC A 101 (-3.2A) None HEC A 101 (-4.0A)	1.34A	2vmyA-1ql4A: undetectable 2vmyB-1ql4A: undetectable	2vmyA-1ql4A: 14.82 2vmyB-1ql4A: 14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKT_A_198A1001_1 (ANDROGEN RECEPTOR)	1ql4	CYTOCHROME C552 (Paracoccus denitrificans)	5 / 12	LEU A 30 GLY A 32 VAL A 38 MET A 50 ILE A 93	HEC A 101 ( 4.6A) None HEC A 101 ( 4.1A) HEC A 101 (-4.4A) None	1.29A	4oktA-1ql4A: undetectable	4oktA-1ql4A: 19.01

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UKB_A_BEZA1300_0","2-HYDROXY-6-OXO-7-METHYLOCTA-2,4-DIENOATE HYDROLASE","1ql4","CYTOCHROME C552","Paracoccus denitrificans",5,"GLY A  55;ALA A  61;LEU A  62;VAL A  73;VAL A  72","None","1.13A","1ukbA-1ql4A:undetectable","1ukbA-1ql4A:16.01"],["1UKB_A_BEZA1300_0","2-HYDROXY-6-OXO-7-METHYLOCTA-2,4-DIENOATE HYDROLASE","1ql4","CYTOCHROME C552","Paracoccus denitrificans",5,"GLY A  55;ALA A  61;VAL A  73;VAL A  72;HIS A  53","None","1.12A","1ukbA-1ql4A:undetectable","1ukbA-1ql4A:16.01"],["2VMY_B_GLYB502_0","SERINE HYDROXYMETHYLTRANSFERASE","1ql4","CYTOCHROME C552","Paracoccus denitrificans",4,"TYR A  46;HIS A  18;HIS A  29;ARG A  36","HEC A 101 (-4.5A);HEC A 101 (-3.2A);None;HEC A 101 (-4.0A)","1.34A","2vmyA-1ql4A:undetectable;2vmyB-1ql4A:undetectable","2vmyA-1ql4A:14.82;2vmyB-1ql4A:14.82"],["4OKT_A_198A1001_1","ANDROGEN RECEPTOR","1ql4","CYTOCHROME C552","Paracoccus denitrificans",5,"LEU A  30;GLY A  32;VAL A  38;MET A  50;ILE A  93","HEC A 101 ( 4.6A);None;HEC A 101 ( 4.1A);HEC A 101 (-4.4A);None","1.29A","4oktA-1ql4A:undetectable","4oktA-1ql4A:19.01"]]