SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qlc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1qlc POSTSYNAPTIC DENSITY
PROTEIN 95
(Rattus
norvegicus) 		4 / 8 SER A 173
ILE A 208
GLY A 209
GLY A 176
 None
 0.76A 1me7A-1qlcA:
undetectable		 1me7A-1qlcA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1qlc POSTSYNAPTIC DENSITY
PROTEIN 95
(Rattus
norvegicus) 		5 / 12 ILE A 194
LEU A 241
VAL A 239
LEU A 220
ILE A 189
 None
 1.07A 3gwxB-1qlcA:
undetectable		 3gwxB-1qlcA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 1qlc POSTSYNAPTIC DENSITY
PROTEIN 95
(Rattus
norvegicus) 		5 / 12 LEU A 206
LYS A 211
VAL A 191
ALA A 200
LEU A 232
 None
 1.21A 4i1rA-1qlcA:
undetectable		 4i1rA-1qlcA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 1qlc POSTSYNAPTIC DENSITY
PROTEIN 95
(Rattus
norvegicus) 		5 / 12 VAL A 215
LEU A 206
ILE A 212
LEU A 170
ALA A 200
 None
 1.00A 4p65B-1qlcA:
undetectable
4p65D-1qlcA:
undetectable
4p65I-1qlcA:
undetectable
4p65J-1qlcA:
undetectable		 4p65B-1qlcA:
20.51
4p65D-1qlcA:
20.51
4p65I-1qlcA:
15.07
4p65J-1qlcA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 1qlc POSTSYNAPTIC DENSITY
PROTEIN 95
(Rattus
norvegicus) 		5 / 12 LEU A 206
VAL A 215
ILE A 212
LEU A 170
ALA A 200
 None
 1.04A 4p65F-1qlcA:
undetectable
4p65H-1qlcA:
undetectable
4p65K-1qlcA:
undetectable
4p65L-1qlcA:
undetectable		 4p65F-1qlcA:
20.51
4p65H-1qlcA:
20.51
4p65K-1qlcA:
15.07
4p65L-1qlcA:
20.51