SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qle'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		3 / 3 VAL C  70
TRP C  65
TRP C  16
 PC1  C 302 (-4.3A)
None
None
 1.32A 1c4dA-1qleC:
undetectable
1c4dB-1qleC:
undetectable		 1c4dA-1qleC:
5.53
1c4dB-1qleC:
5.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 GLU B 153
TYR B 149
PHE B 213
 None
 0.75A 1eqbB-1qleB:
undetectable		 1eqbB-1qleB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 GLU B 153
TYR B 149
PHE B 213
 None
 0.76A 1eqbA-1qleB:
undetectable		 1eqbA-1qleB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 GLU B 153
TYR B 149
PHE B 213
 None
 0.76A 1eqbD-1qleB:
undetectable		 1eqbD-1qleB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 GLU B 153
TYR B 149
PHE B 213
 None
 0.77A 1eqbC-1qleB:
undetectable		 1eqbC-1qleB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQU_A_EQIA329_0
(PROTEIN (ESTRADIOL
17
BETA-DEHYDROGENASE
1))		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 10 VAL A 165
TYR A 267
GLY A 163
HIS A 403
ARG A 474
 None
None
HEA  A 601 (-3.6A)
MN  B 302 ( 3.2A)
HEA  A 601 ( 3.0A)
 1.33A 1equA-1qleA:
undetectable		 1equA-1qleA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 ALA A 426
VAL A 428
TRP A 431
 None
 0.89A 1grmA-1qleA:
undetectable		 1grmA-1qleA:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 ALA A 426
VAL A 428
TRP A 431
 None
 0.89A 1grmB-1qleA:
undetectable		 1grmB-1qleA:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 PHE A 297
TYR A 440
PRO A 372
 None
 1.15A 1mcnA-1qleA:
undetectable
1mcnB-1qleA:
undetectable
1mcnP-1qleA:
undetectable		 1mcnA-1qleA:
15.34
1mcnB-1qleA:
15.34
1mcnP-1qleA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 HIS A 326
PHE A 273
GLY A 275
ALA A 324
HIS A 325
 CU  A 603 ( 3.3A)
PC1  C 301 ( 4.8A)
None
None
CU  A 603 ( 3.4A)
 1.03A 1mjqC-1qleA:
undetectable
1mjqD-1qleA:
undetectable		 1mjqC-1qleA:
11.11
1mjqD-1qleA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 HIS A 326
PHE A 273
GLY A 275
ALA A 324
HIS A 325
 CU  A 603 ( 3.3A)
PC1  C 301 ( 4.8A)
None
None
CU  A 603 ( 3.4A)
 1.02A 1mjqI-1qleA:
undetectable
1mjqJ-1qleA:
undetectable		 1mjqI-1qleA:
11.11
1mjqJ-1qleA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 ILE A 226
GLY A 286
ALA A 426
SER A 291
HIS A 292
 None
 1.20A 1nbhA-1qleA:
undetectable		 1nbhA-1qleA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 ILE A 226
GLY A 286
ALA A 426
SER A 291
HIS A 292
 None
 1.20A 1nbhC-1qleA:
undetectable		 1nbhC-1qleA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 ILE A 226
GLY A 286
ALA A 426
SER A 291
HIS A 292
 None
 1.20A 1nbhD-1qleA:
undetectable		 1nbhD-1qleA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		5 / 12 GLY C 214
VAL C 260
ALA C 190
LEU C 200
PHE C 101
 None
 1.21A 1nw3A-1qleC:
undetectable		 1nw3A-1qleC:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 8 ILE A  33
LEU A  36
PHE A 111
GLY A 427
 None
 1.07A 1os6A-1qleA:
undetectable		 1os6A-1qleA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 6 LEU C  92
LEU A 205
TRP A 229
PHE A 225
 None
 1.23A 1ru9H-1qleC:
undetectable
1ru9L-1qleC:
undetectable		 1ru9H-1qleC:
20.57
1ru9L-1qleC:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 8 VAL A 237
TRP A 272
HIS A 325
GLU A 278
 None
None
CU  A 603 ( 3.4A)
None
 1.23A 1s3zA-1qleA:
undetectable
1s3zB-1qleA:
undetectable		 1s3zA-1qleA:
13.48
1s3zB-1qleA:
13.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.25A 1v54A-1qleA:
54.5		 1v54A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 1v54A-1qleA:
54.5
1v54C-1qleA:
2.7		 1v54A-1qleA:
53.19
1v54C-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.28A 1v54N-1qleA:
54.5		 1v54N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.61A 1v54N-1qleA:
54.5
1v54P-1qleA:
0.9		 1v54N-1qleA:
53.19
1v54P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.28A 1v55A-1qleA:
54.4		 1v55A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 1v55A-1qleA:
54.4
1v55C-1qleA:
2.7		 1v55A-1qleA:
53.19
1v55C-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.25A 1v55N-1qleA:
54.4		 1v55N-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 ILE A 424
ALA A 106
MET A 452
PHE A 425
PHE A 503
 None
HEA  A 601 (-3.3A)
HEA  A 601 (-4.1A)
None
None
 1.20A 1y0xX-1qleA:
undetectable		 1y0xX-1qleA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		4 / 6 LEU C 227
ALA C 158
HIS C 255
ASP C 258
 None
 1.35A 2dpzA-1qleC:
undetectable		 2dpzA-1qleC:
15.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 2dyrA-1qleA:
54.5		 2dyrA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 2dyrA-1qleA:
54.5
2dyrC-1qleA:
2.7		 2dyrA-1qleA:
53.19
2dyrC-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.28A 2dyrN-1qleA:
54.5		 2dyrN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 2dyrN-1qleA:
54.5
2dyrP-1qleA:
2.7		 2dyrN-1qleA:
53.19
2dyrP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 2dysA-1qleA:
54.5		 2dysA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 2dysN-1qleA:
54.5		 2dysN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 2eijA-1qleA:
54.4		 2eijA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.57A 2eijA-1qleA:
54.4
2eijC-1qleA:
2.7		 2eijA-1qleA:
53.19
2eijC-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 2eijN-1qleA:
54.4		 2eijN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 2eijN-1qleA:
54.4
2eijP-1qleA:
2.7		 2eijN-1qleA:
53.19
2eijP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.20A 2eikA-1qleA:
54.4		 2eikA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.57A 2eikA-1qleA:
54.4
2eikC-1qleA:
2.7		 2eikA-1qleA:
53.19
2eikC-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.28A 2eikN-1qleA:
54.4		 2eikN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.56A 2eikN-1qleA:
54.4
2eikP-1qleA:
2.7		 2eikN-1qleA:
53.19
2eikP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 2eilA-1qleA:
54.5		 2eilA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 2eilA-1qleA:
54.5
2eilC-1qleA:
2.7		 2eilA-1qleA:
53.19
2eilC-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.27A 2eilN-1qleA:
54.5		 2eilN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 2eilN-1qleA:
54.5
2eilP-1qleA:
2.7		 2eilN-1qleA:
53.19
2eilP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.26A 2eimA-1qleA:
54.2		 2eimA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.30A 2eimN-1qleA:
54.2		 2eimN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 2einA-1qleA:
54.3		 2einA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.35A 2einN-1qleA:
54.3		 2einN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		5 / 12 ASN B 223
GLY A 470
ASP A 477
PRO A 479
PHE A 482
 None
 1.15A 2f8lA-1qleB:
undetectable		 2f8lA-1qleB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 5 ILE A 242
PHE A 256
PHE A 255
ILE A 270
 None
 1.08A 2hjhA-1qleA:
undetectable		 2hjhA-1qleA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		3 / 3 LYS C 110
GLY B 197
PRO B 196
 PC1  C 301 (-4.5A)
None
None
 0.81A 2hreB-1qleC:
undetectable		 2hreB-1qleC:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1598_0
(NITROUS OXIDE
REDUCTASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		4 / 4 HIS B 181
CYH B 216
CYH B 220
MET B 227
 CUA  B 301 (-3.2A)
CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-2.5A)
 0.50A 2iwkA-1qleB:
9.4		 2iwkA-1qleB:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 CYH B 216
CYH B 220
HIS B 224
 CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-3.1A)
 0.35A 2iwkA-1qleB:
9.4		 2iwkA-1qleB:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1598_0
(NITROUS OXIDE
REDUCTASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		4 / 4 HIS B 181
CYH B 216
CYH B 220
MET B 227
 CUA  B 301 (-3.2A)
CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-2.5A)
 0.51A 2iwkB-1qleB:
9.4		 2iwkB-1qleB:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 CYH B 216
CYH B 220
HIS B 224
 CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-3.1A)
 0.36A 2iwkB-1qleB:
9.4		 2iwkB-1qleB:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		3 / 3 PHE A  19
PHE C  18
PHE C  19
 None
 0.80A 2od9A-1qleA:
undetectable		 2od9A-1qleA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 325
HIS A 326
HIS A 276
 CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
CU  A 603 (-3.2A)
 0.72A 2oqeA-1qleA:
undetectable		 2oqeA-1qleA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 325
HIS A 326
HIS A 276
 CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
CU  A 603 (-3.2A)
 0.71A 2oqeB-1qleA:
undetectable		 2oqeB-1qleA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 325
HIS A 326
HIS A 276
 CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
CU  A 603 (-3.2A)
 0.72A 2oqeC-1qleA:
undetectable		 2oqeC-1qleA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 325
HIS A 326
HIS A 276
 CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
CU  A 603 (-3.2A)
 0.70A 2oqeD-1qleA:
undetectable		 2oqeD-1qleA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 325
HIS A 326
HIS A 276
 CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
CU  A 603 (-3.2A)
 0.71A 2oqeF-1qleA:
undetectable		 2oqeF-1qleA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		3 / 3 PHE A  19
PHE C  18
PHE C  19
 None
 0.80A 2qqgA-1qleA:
undetectable		 2qqgA-1qleA:
21.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.61A 2y69A-1qleA:
54.5
2y69C-1qleA:
2.7		 2y69A-1qleA:
53.19
2y69C-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.17A 2y69A-1qleA:
54.5		 2y69A-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.53A 2y69C-1qleA:
2.7
2y69N-1qleA:
54.5
2y69P-1qleA:
2.7		 2y69C-1qleA:
20.59
2y69N-1qleA:
53.19
2y69P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.08A 2y69N-1qleA:
54.5		 2y69N-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		4 / 6 MET A 308
PRO A 350
GLY A 352
TRP B  81
 None
None
HEA  A 602 ( 3.7A)
None
 1.17A 2y7pA-1qleA:
undetectable		 2y7pA-1qleA:
18.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 2zxwA-1qleA:
54.3		 2zxwA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.19A 2zxwN-1qleA:
54.4		 2zxwN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.25A 3abkA-1qleA:
54.3		 3abkA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 3abkA-1qleA:
54.3
3abkC-1qleA:
2.3		 3abkA-1qleA:
53.19
3abkC-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.16A 3abkN-1qleA:
54.3		 3abkN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.56A 3abkN-1qleA:
54.3
3abkP-1qleA:
2.7		 3abkN-1qleA:
53.19
3abkP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 3ablA-1qleA:
54.4		 3ablA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.67A 3ablA-1qleA:
54.4
3ablC-1qleA:
2.9
3ablP-1qleA:
2.7		 3ablA-1qleA:
53.19
3ablC-1qleA:
20.59
3ablP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 3ablN-1qleA:
54.4		 3ablN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.63A 3ablC-1qleA:
2.9
3ablN-1qleA:
54.4
3ablP-1qleA:
2.7		 3ablC-1qleA:
20.59
3ablN-1qleA:
53.19
3ablP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 3abmA-1qleA:
54.4		 3abmA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 3abmA-1qleA:
54.4
3abmC-1qleA:
2.7
3abmP-1qleA:
2.7		 3abmA-1qleA:
53.19
3abmC-1qleA:
20.59
3abmP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.12A 3abmN-1qleA:
54.4		 3abmN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 3abmN-1qleA:
54.4
3abmP-1qleA:
2.7		 3abmN-1qleA:
53.19
3abmP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 3ag1A-1qleA:
54.1		 3ag1A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.19A 3ag1N-1qleA:
54.1		 3ag1N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.64A 3ag2A-1qleA:
54.4
3ag2C-1qleA:
2.7		 3ag2A-1qleA:
53.19
3ag2C-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 3ag2A-1qleA:
54.4		 3ag2A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.26A 3ag2N-1qleA:
54.5		 3ag2N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 3ag2N-1qleA:
54.5
3ag2P-1qleA:
2.7		 3ag2N-1qleA:
53.19
3ag2P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 3ag3A-1qleA:
54.3		 3ag3A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.57A 3ag3A-1qleA:
54.3
3ag3C-1qleA:
2.7		 3ag3A-1qleA:
53.19
3ag3C-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.21A 3ag3N-1qleA:
54.4		 3ag3N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.62A 3ag3N-1qleA:
54.4
3ag3P-1qleA:
2.7		 3ag3N-1qleA:
53.19
3ag3P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.40A 3ag4A-1qleA:
54.1		 3ag4A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 3ag4A-1qleA:
54.1
3ag4C-1qleA:
2.7		 3ag4A-1qleA:
53.19
3ag4C-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.31A 3ag4N-1qleA:
54.1		 3ag4N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.51A 3ag4N-1qleA:
54.1
3ag4P-1qleA:
2.7		 3ag4N-1qleA:
53.19
3ag4P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.09A 3asnA-1qleA:
54.5		 3asnA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.16A 3asnN-1qleA:
54.5		 3asnN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 3asnC-1qleA:
2.7
3asnN-1qleA:
54.5
3asnP-1qleA:
2.7		 3asnC-1qleA:
20.59
3asnN-1qleA:
53.19
3asnP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.12A 3asoA-1qleA:
54.5		 3asoA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 3asoA-1qleA:
54.5
3asoC-1qleA:
2.7
3asoP-1qleA:
2.7		 3asoA-1qleA:
53.19
3asoC-1qleA:
20.59
3asoP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.19A 3asoN-1qleA:
54.5		 3asoN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 3asoC-1qleA:
2.7
3asoN-1qleA:
54.5
3asoP-1qleA:
2.7		 3asoC-1qleA:
20.59
3asoN-1qleA:
53.19
3asoP-1qleA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		4 / 5 VAL C  69
VAL C  70
GLN C 243
PHE C  90
 PC1  C 302 (-4.2A)
PC1  C 302 (-4.3A)
PC1  C 302 (-2.9A)
PC1  C 302 (-4.4A)
 1.37A 3bjwH-1qleC:
0.5		 3bjwH-1qleC:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.40A 3bvdA-1qleA:
34.6		 3bvdA-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 LEU A 149
VAL A 162
GLY A 161
GLY A 159
THR A  92
 None
 1.25A 3dh0A-1qleA:
undetectable		 3dh0A-1qleA:
17.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 3dtuA-1qleA:
58.8		 3dtuA-1qleA:
82.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_B_CUB1004_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		4 / 4 HIS B 181
CYH B 216
CYH B 220
MET B 227
 CUA  B 301 (-3.2A)
CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-2.5A)
 0.29A 3dtuB-1qleB:
29.3		 3dtuB-1qleB:
56.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 CYH B 216
CYH B 220
HIS B 224
 CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-3.1A)
 0.26A 3dtuB-1qleB:
29.3		 3dtuB-1qleB:
56.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 3dtuC-1qleA:
58.9		 3dtuC-1qleA:
82.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		6 / 8 PRO A 307
ALA A 311
ALA A 314
PRO A 350
ILE A 353
HIS B  73
 None
 0.94A 3dtuC-1qleA:
58.9
3dtuD-1qleA:
undetectable		 3dtuC-1qleA:
82.85
3dtuD-1qleA:
19.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		6 / 8 PRO A 307
ALA A 311
ALA A 314
PRO A 350
ILE A 353
THR B  82
 None
 0.24A 3dtuC-1qleA:
58.9
3dtuD-1qleA:
undetectable		 3dtuC-1qleA:
82.85
3dtuD-1qleA:
19.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 CYH B 216
CYH B 220
HIS B 224
 CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-3.1A)
 0.22A 3dtuD-1qleB:
29.5		 3dtuD-1qleB:
56.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_D_CUD4_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		4 / 4 HIS B 181
CYH B 216
CYH B 220
MET B 227
 CUA  B 301 (-3.2A)
CUA  B 301 (-2.1A)
CUA  B 301 (-2.0A)
CUA  B 301 (-2.5A)
 0.30A 3dtuD-1qleB:
29.5		 3dtuD-1qleB:
56.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 7 ILE A 294
PHE A 449
PHE A 422
GLY A 288
 None
 0.67A 3em0B-1qleA:
0.0		 3em0B-1qleA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		3 / 3 ILE A 194
PHE C  93
HIS A 187
 None
 0.73A 3h0aA-1qleA:
0.2		 3h0aA-1qleA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 325
HIS A 326
HIS A 276
 CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
CU  A 603 (-3.2A)
 0.65A 3hiiA-1qleA:
undetectable		 3hiiA-1qleA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 325
HIS A 326
HIS A 276
 CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
CU  A 603 (-3.2A)
 0.66A 3hiiB-1qleA:
undetectable		 3hiiB-1qleA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 8 GLY A  95
ILE A 282
PHE A 422
PHE A 425
 HEA  A 601 ( 4.0A)
HEA  A 602 ( 4.7A)
None
None
 1.03A 3ko0B-1qleA:
undetectable
3ko0J-1qleA:
undetectable		 3ko0B-1qleA:
10.65
3ko0J-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 9 GLY A  43
GLY A  95
ILE A 282
PHE A 422
PHE A 425
 HEA  A 601 ( 4.1A)
HEA  A 601 ( 4.0A)
HEA  A 602 ( 4.7A)
None
None
 1.21A 3ko0F-1qleA:
undetectable
3ko0G-1qleA:
undetectable		 3ko0F-1qleA:
10.65
3ko0G-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 9 GLY A  43
GLY A  95
ILE A 282
PHE A 422
PHE A 425
 HEA  A 601 ( 4.1A)
HEA  A 601 ( 4.0A)
HEA  A 602 ( 4.7A)
None
None
 1.13A 3ko0H-1qleA:
undetectable
3ko0I-1qleA:
undetectable		 3ko0H-1qleA:
10.65
3ko0I-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 8 GLY A  95
ILE A 282
PHE A 422
PHE A 425
 HEA  A 601 ( 4.0A)
HEA  A 602 ( 4.7A)
None
None
 1.05A 3ko0K-1qleA:
undetectable
3ko0S-1qleA:
undetectable		 3ko0K-1qleA:
10.65
3ko0S-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 10 GLY A  43
GLY A  95
ILE A 282
PHE A 422
PHE A 425
 HEA  A 601 ( 4.1A)
HEA  A 601 ( 4.0A)
HEA  A 602 ( 4.7A)
None
None
 1.13A 3ko0L-1qleA:
undetectable
3ko0N-1qleA:
undetectable		 3ko0L-1qleA:
10.65
3ko0N-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 8 GLY A 387
PHE A 449
GLY A 419
PHE A 422
 HEA  A 602 (-3.3A)
None
None
None
 0.64A 3ko0O-1qleA:
undetectable
3ko0Q-1qleA:
0.1		 3ko0O-1qleA:
10.65
3ko0Q-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 10 GLY A  95
ILE A 282
PHE A 422
PHE A 425
GLY A  43
 HEA  A 601 ( 4.0A)
HEA  A 602 ( 4.7A)
None
None
HEA  A 601 ( 4.1A)
 1.21A 3ko0R-1qleA:
undetectable
3ko0T-1qleA:
undetectable		 3ko0R-1qleA:
10.65
3ko0T-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		4 / 7 PHE A 204
GLY C  85
MET A 212
PHE A 215
 None
 1.13A 3ko0K-1qleA:
undetectable
3ko0S-1qleA:
undetectable		 3ko0K-1qleA:
10.65
3ko0S-1qleA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		4 / 8 PHE C  19
VAL C  61
GLY C  57
GLY C  20
 None
 0.78A 3n9jB-1qleC:
undetectable		 3n9jB-1qleC:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		4 / 8 GLY C 237
LEU C 235
LEU C 234
ILE C 172
 None
 0.91A 3nbqB-1qleC:
undetectable		 3nbqB-1qleC:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 9 PRO A 285
ILE A 104
ILE A 282
THR A 227
ILE A 231
 None
None
HEA  A 602 ( 4.7A)
None
None
 1.16A 3p4wB-1qleA:
2.4		 3p4wB-1qleA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 10 PRO A 285
ILE A 104
ILE A 282
THR A 227
ILE A 231
 None
None
HEA  A 602 ( 4.7A)
None
None
 1.16A 3p4wD-1qleA:
undetectable		 3p4wD-1qleA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 10 PRO A 285
ILE A 104
ILE A 282
THR A 227
ILE A 231
 None
None
HEA  A 602 ( 4.7A)
None
None
 1.15A 3p4wE-1qleA:
2.0		 3p4wE-1qleA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.34A 3s33A-1qleA:
34.4		 3s33A-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.45A 3s38A-1qleA:
34.3		 3s38A-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.34A 3s39A-1qleA:
34.5		 3s39A-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.34A 3s3aA-1qleA:
34.1		 3s3aA-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.33A 3s3bA-1qleA:
34.6		 3s3bA-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.40A 3s3cA-1qleA:
34.5		 3s3cA-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.35A 3s3dA-1qleA:
34.5		 3s3dA-1qleA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 6 ILE A  33
LEU A  36
PHE A 111
GLY A 427
 None
 0.96A 3sj1X-1qleA:
undetectable		 3sj1X-1qleA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 HIS A  28
ASP A 124
LEU A 530
PHE A 543
ALA A 122
 None
 0.83A 3sufA-1qleA:
undetectable		 3sufA-1qleA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		4 / 7 LEU A 266
GLY A 240
ALA C 103
PHE C 100
 None
 1.01A 3tehB-1qleA:
undetectable		 3tehB-1qleA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 7 ILE A 454
GLY A 455
SER A 456
PHE A 422
LEU A 418
 None
None
HEA  A 601 ( 4.3A)
None
None
 1.23A 3v7pA-1qleA:
undetectable		 3v7pA-1qleA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 8 ILE A 242
LEU A 245
VAL A 162
GLY A 163
 None
None
None
HEA  A 601 (-3.6A)
 0.73A 3w1wA-1qleA:
undetectable		 3w1wA-1qleA:
20.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.15A 3wg7A-1qleA:
54.3		 3wg7A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 3wg7A-1qleA:
54.3
3wg7C-1qleA:
2.7
3wg7P-1qleA:
2.7		 3wg7A-1qleA:
53.19
3wg7C-1qleA:
20.59
3wg7P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 3wg7N-1qleA:
54.3		 3wg7N-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.61A 3wg7C-1qleA:
2.7
3wg7N-1qleA:
54.3
3wg7P-1qleA:
2.7		 3wg7C-1qleA:
20.59
3wg7N-1qleA:
53.19
3wg7P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 3x2qA-1qleA:
54.4		 3x2qA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.61A 3x2qA-1qleA:
54.4
3x2qC-1qleA:
2.7
3x2qP-1qleA:
2.7		 3x2qA-1qleA:
53.19
3x2qC-1qleA:
20.59
3x2qP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.15A 3x2qN-1qleA:
54.5		 3x2qN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.56A 3x2qC-1qleA:
2.7
3x2qN-1qleA:
54.5
3x2qP-1qleA:
2.7		 3x2qC-1qleA:
20.59
3x2qN-1qleA:
53.19
3x2qP-1qleA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		4 / 7 LEU B 155
VAL A  62
TYR A 475
TYR B 154
 None
 1.13A 4b3qA-1qleB:
undetectable		 4b3qA-1qleB:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 VAL A 385
GLY A 386
VAL A 415
PHE A 460
HIS A 413
 None
None
HEA  A 602 (-4.2A)
None
HEA  A 601 (-3.4A)
 1.45A 4bvaA-1qleA:
undetectable		 4bvaA-1qleA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 VAL A 385
GLY A 386
VAL A 415
PHE A 460
HIS A 413
 None
None
HEA  A 602 (-4.2A)
None
HEA  A 601 (-3.4A)
 1.49A 4bvaB-1qleA:
undetectable		 4bvaB-1qleA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 10 LEU A 501
ILE A 504
GLY A 505
PHE A 497
SER A 496
 None
None
None
None
HEA  A 601 ( 4.2A)
 0.85A 4fakA-1qleA:
undetectable		 4fakA-1qleA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 7 ILE A  33
LEU A  36
PHE A 111
GLY A 427
 None
 0.94A 4hbfA-1qleA:
undetectable		 4hbfA-1qleA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 7 ILE A  33
LEU A  36
PHE A 111
GLY A 427
 None
 1.02A 4hc3A-1qleA:
undetectable		 4hc3A-1qleA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		4 / 8 GLY A 112
ASN A 113
PRO A 285
ILE A 104
 None
 0.98A 4j4vC-1qleA:
0.2		 4j4vC-1qleA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1qle CCYTOCHROME C
OXIDASE
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans) 		4 / 6 TYR C   8
ILE D  16
THR C  79
GLY D  12
 None
 1.03A 4l39A-1qleC:
0.0		 4l39A-1qleC:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 ASP A 528
ASN A 521
SER A 291
 None
 0.86A 4obwA-1qleA:
undetectable		 4obwA-1qleA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		5 / 12 GLY A 467
ASN B  15
GLY B  16
ARG A  54
ASN A 486
 None
None
None
HEA  A 601 (-3.1A)
None
 1.14A 4obwD-1qleA:
undetectable		 4obwD-1qleA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		3 / 3 ALA B 189
GLN A 469
GLY B  17
 None
 0.64A 4odoC-1qleB:
undetectable		 4odoC-1qleB:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		6 / 12 GLY A 153
GLU A 174
GLY A 159
GLY A 161
ASN A  88
SER A 178
 None
 1.33A 4uciA-1qleA:
undetectable		 4uciA-1qleA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		6 / 12 GLY A 153
GLU A 174
GLY A 159
GLY A 161
ASN A  88
SER A 178
 None
 1.32A 4uciB-1qleA:
undetectable		 4uciB-1qleA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		6 / 12 GLY A 153
GLU A 174
GLY A 159
GLY A 161
ASN A  88
SER A 178
 None
 1.33A 4uckA-1qleA:
undetectable		 4uckA-1qleA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		6 / 12 GLY A 153
GLU A 174
GLY A 159
GLY A 161
ASN A  88
THR C  39
 None
 1.36A 4uckA-1qleA:
undetectable		 4uckA-1qleA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		5 / 12 SER B 205
VAL B 172
LEU B 100
LEU B  27
ALA B 189
 None
 1.25A 4x1kA-1qleB:
undetectable
4x1kB-1qleB:
undetectable		 4x1kA-1qleB:
20.32
4x1kB-1qleB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE II
HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Paracoccus
denitrificans;
Mus
musculus) 		4 / 5 TYR H 101
TYR H  32
GLU B 209
ASP B   6
 None
 1.47A 4x61A-1qleH:
undetectable		 4x61A-1qleH:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		5 / 12 THR A 405
LEU A  57
ARG A  54
HIS B 224
PRO B  13
 None
None
HEA  A 601 (-3.1A)
CUA  B 301 (-3.1A)
None
 1.31A 4xi3A-1qleA:
2.1		 4xi3A-1qleA:
17.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.16A 5b1aA-1qleA:
54.4		 5b1aA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.62A 5b1aA-1qleA:
54.4
5b1aC-1qleA:
2.7
5b1aP-1qleA:
2.7		 5b1aA-1qleA:
53.19
5b1aC-1qleA:
20.59
5b1aP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.26A 5b1aN-1qleA:
54.5		 5b1aN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 5b1aN-1qleA:
54.5
5b1aP-1qleA:
2.7		 5b1aN-1qleA:
53.19
5b1aP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 5b1bA-1qleA:
54.3		 5b1bA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 5b1bA-1qleA:
54.3
5b1bC-1qleA:
2.7
5b1bP-1qleA:
2.7		 5b1bA-1qleA:
53.19
5b1bC-1qleA:
20.59
5b1bP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.29A 5b1bN-1qleA:
54.3		 5b1bN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 5b1bN-1qleA:
54.3
5b1bP-1qleA:
2.7		 5b1bN-1qleA:
53.19
5b1bP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 5b3sA-1qleA:
54.5		 5b3sA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.62A 5b3sA-1qleA:
54.5
5b3sC-1qleA:
2.7
5b3sP-1qleA:
2.7		 5b3sA-1qleA:
53.19
5b3sC-1qleA:
20.59
5b3sP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.29A 5b3sN-1qleA:
54.5		 5b3sN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.52A 5b3sN-1qleA:
54.5
5b3sP-1qleA:
2.7		 5b3sN-1qleA:
53.19
5b3sP-1qleA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1qle HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Mus
musculus) 		4 / 7 ALA H  92
THR H  91
VAL H 114
GLU H  89
 None
 0.71A 5ecmD-1qleH:
undetectable		 5ecmD-1qleH:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1qle HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Mus
musculus) 		4 / 8 ALA H  92
THR H  91
VAL H 114
GLU H  89
 None
 0.71A 5ecnD-1qleH:
undetectable		 5ecnD-1qleH:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans) 		5 / 10 ILE A 315
TYR A 280
LEU A 284
PHE A 287
ILE B  42
 None
HEA  A 602 (-4.7A)
None
None
None
 1.29A 5hw8C-1qleA:
undetectable
5hw8H-1qleA:
undetectable		 5hw8C-1qleA:
14.15
5hw8H-1qleA:
14.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 5iy5A-1qleA:
54.4		 5iy5A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.61A 5iy5A-1qleA:
54.4
5iy5C-1qleA:
2.7		 5iy5A-1qleA:
53.19
5iy5C-1qleA:
20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 5iy5N-1qleA:
54.3		 5iy5N-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.55A 5iy5C-1qleA:
2.7
5iy5N-1qleA:
54.3
5iy5P-1qleA:
2.7		 5iy5C-1qleA:
20.37
5iy5N-1qleA:
53.19
5iy5P-1qleA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1qle HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.87A 5jsdA-1qleH:
undetectable		 5jsdA-1qleH:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1qle HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.87A 5jsdB-1qleH:
2.8		 5jsdB-1qleH:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1qle HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.86A 5jsdC-1qleH:
2.5		 5jsdC-1qleH:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1qle HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.89A 5jseB-1qleH:
2.8		 5jseB-1qleH:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1qle HEAVY CHAIN ANTIBODY
FV FRAGMENT
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.88A 5jseC-1qleH:
2.5		 5jseC-1qleH:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE II
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		5 / 12 TYR A 328
ILE B 199
ALA B 116
ASP B 193
ALA B 194
 None
None
None
MN  B 302 ( 3.9A)
None
 1.15A 5kvaB-1qleA:
undetectable		 5kvaB-1qleA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 ILE A 283
PHE A 287
GLY A 288
HIS A 292
GLY A 286
 HEA  A 602 ( 4.3A)
None
None
None
None
 1.18A 5l6eA-1qleA:
undetectable		 5l6eA-1qleA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 ILE A 424
GLY A 423
VAL A 293
PHE A 220
ALA A 106
 None
None
None
None
HEA  A 601 (-3.3A)
 1.24A 5n0xB-1qleA:
undetectable		 5n0xB-1qleA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 GLY A 176
GLY A 159
GLY A 154
VAL A  96
PHE A 101
 None
 0.95A 5vimA-1qleA:
undetectable		 5vimA-1qleA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 GLY A 176
GLY A 159
GLY A 154
VAL A  96
PHE A 101
 None
 0.95A 5vimB-1qleA:
undetectable		 5vimB-1qleA:
17.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 5w97a-1qleA:
54.1		 5w97a-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.56A 5w97A-1qleA:
54.1
5w97C-1qleA:
2.7
5w97c-1qleA:
2.7		 5w97A-1qleA:
53.19
5w97C-1qleA:
20.59
5w97c-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.21A 5waua-1qleA:
54.5		 5waua-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.54A 5wauA-1qleA:
54.5
5wauC-1qleA:
2.7
5wauc-1qleA:
2.7		 5wauA-1qleA:
53.19
5wauC-1qleA:
20.59
5wauc-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.25A 5x19A-1qleA:
54.2		 5x19A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 5x19A-1qleA:
54.2
5x19C-1qleA:
2.3
5x19P-1qleA:
2.7		 5x19A-1qleA:
53.19
5x19C-1qleA:
20.59
5x19P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.27A 5x19N-1qleA:
54.2		 5x19N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.26A 5x1bA-1qleA:
53.8		 5x1bA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 5x1bN-1qleA:
53.7		 5x1bN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.26A 5x1fA-1qleA:
54.2		 5x1fA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.21A 5x1fN-1qleA:
54.2		 5x1fN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.56A 5x1fN-1qleA:
54.2
5x1fP-1qleA:
2.6		 5x1fN-1qleA:
53.19
5x1fP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.12A 5xdqA-1qleA:
54.4		 5xdqA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.62A 5xdqA-1qleA:
54.4
5xdqC-1qleA:
2.7
5xdqP-1qleA:
2.7		 5xdqA-1qleA:
53.19
5xdqC-1qleA:
20.59
5xdqP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.16A 5xdqN-1qleA:
54.4		 5xdqN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 5xdqC-1qleA:
2.7
5xdqN-1qleA:
54.4
5xdqP-1qleA:
2.7		 5xdqC-1qleA:
20.59
5xdqN-1qleA:
53.19
5xdqP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.18A 5xdxA-1qleA:
54.3		 5xdxA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDX_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		5 / 9 HIS A 269
TRP A 323
MET A 332
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.64A 5xdxA-1qleA:
54.3
5xdxC-1qleA:
2.7
5xdxP-1qleA:
0.9		 5xdxA-1qleA:
53.19
5xdxC-1qleA:
19.01
5xdxP-1qleA:
19.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.15A 5xdxN-1qleA:
54.3		 5xdxN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.57A 5xdxC-1qleA:
2.7
5xdxN-1qleA:
54.3
5xdxP-1qleA:
2.7		 5xdxC-1qleA:
19.01
5xdxN-1qleA:
53.19
5xdxP-1qleA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		5 / 12 GLY C 214
THR C 213
GLY C 217
THR A 243
LEU A 246
 None
 1.13A 5ybbA-1qleC:
undetectable		 5ybbA-1qleC:
18.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.23A 5z84A-1qleA:
54.5		 5z84A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 5z84A-1qleA:
54.5
5z84C-1qleA:
2.7
5z84P-1qleA:
2.7		 5z84A-1qleA:
53.19
5z84C-1qleA:
20.59
5z84P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 5z84N-1qleA:
54.5		 5z84N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 5z85A-1qleA:
54.5		 5z85A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.56A 5z85A-1qleA:
54.5
5z85C-1qleA:
2.7
5z85P-1qleA:
2.7		 5z85A-1qleA:
53.19
5z85C-1qleA:
20.59
5z85P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 5z85N-1qleA:
54.5		 5z85N-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.00A 5z86A-1qleA:
54.5		 5z86A-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 5z86A-1qleA:
54.5
5z86C-1qleA:
2.7
5z86P-1qleA:
2.7		 5z86A-1qleA:
53.19
5z86C-1qleA:
20.59
5z86P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.18A 5z86N-1qleA:
54.5		 5z86N-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.57A 5z86C-1qleA:
2.7
5z86N-1qleA:
54.5
5z86P-1qleA:
2.7		 5z86C-1qleA:
20.59
5z86N-1qleA:
53.19
5z86P-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 5zcoA-1qleA:
54.4		 5zcoA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 5zcoA-1qleA:
54.4
5zcoC-1qleA:
2.7
5zcoP-1qleA:
2.2		 5zcoA-1qleA:
53.19
5zcoC-1qleA:
20.59
5zcoP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.19A 5zcoN-1qleA:
54.5		 5zcoN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.60A 5zcoC-1qleA:
2.7
5zcoN-1qleA:
54.5
5zcoP-1qleA:
2.2		 5zcoC-1qleA:
20.59
5zcoN-1qleA:
53.19
5zcoP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.17A 5zcpA-1qleA:
54.5		 5zcpA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.56A 5zcpA-1qleA:
54.5
5zcpC-1qleA:
2.7
5zcpP-1qleA:
2.7		 5zcpA-1qleA:
53.19
5zcpC-1qleA:
20.59
5zcpP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.25A 5zcpN-1qleA:
54.5		 5zcpN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.58A 5zcpC-1qleA:
2.7
5zcpN-1qleA:
54.5
5zcpP-1qleA:
2.7		 5zcpC-1qleA:
20.59
5zcpN-1qleA:
53.19
5zcpP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.17A 5zcqA-1qleA:
54.5		 5zcqA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.57A 5zcqA-1qleA:
54.5
5zcqC-1qleA:
2.7
5zcqP-1qleA:
2.7		 5zcqA-1qleA:
53.19
5zcqC-1qleA:
20.59
5zcqP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.19A 5zcqN-1qleA:
54.5		 5zcqN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.59A 5zcqN-1qleA:
54.5
5zcqP-1qleA:
2.7		 5zcqN-1qleA:
53.19
5zcqP-1qleA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 HIS A 411
GLY A 286
THR A 384
GLY A 387
GLY A 386
 HEA  A 602 (-3.4A)
None
HEA  A 602 ( 4.7A)
HEA  A 602 (-3.3A)
None
 1.22A 6brdB-1qleA:
0.0		 6brdB-1qleA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 HIS A 411
GLY A 423
THR A 384
GLY A 387
GLY A 386
 HEA  A 602 (-3.4A)
None
HEA  A 602 ( 4.7A)
HEA  A 602 (-3.3A)
None
 1.16A 6brdB-1qleA:
0.0		 6brdB-1qleA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		3 / 3 LEU A 149
ASP A 180
ILE C  38
 None
 0.59A 6dh0B-1qleA:
undetectable		 6dh0B-1qleA:
14.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.64A 6giqa-1qleA:
46.6		 6giqa-1qleA:
52.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.15A 6hu9a-1qleA:
52.8		 6hu9a-1qleA:
52.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.27A 6hu9m-1qleA:
52.7		 6hu9m-1qleA:
52.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		5 / 12 ILE A 120
ILE A 200
VAL A 217
HIS A 292
PHE A 220
 None
 1.32A 6j21A-1qleA:
2.3		 6j21A-1qleA:
21.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.21A 6nknA-1qleA:
54.0		 6nknA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.19A 6nknN-1qleA:
53.9		 6nknN-1qleA:
53.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 8 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.57A 6nknC-1qleA:
2.8
6nknN-1qleA:
53.9
6nknP-1qleA:
2.7		 6nknC-1qleA:
20.59
6nknN-1qleA:
53.19
6nknP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.24A 6nmfA-1qleA:
53.9		 6nmfA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.22A 6nmfN-1qleA:
53.7		 6nmfN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.62A 6nmfN-1qleA:
53.7
6nmfP-1qleA:
2.7		 6nmfN-1qleA:
53.19
6nmfP-1qleA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.14A 6nmpA-1qleA:
54.0		 6nmpA-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
(Paracoccus
denitrificans) 		3 / 3 HIS A 276
HIS A 325
HIS A 326
 CU  A 603 (-3.2A)
CU  A 603 ( 3.4A)
CU  A 603 ( 3.3A)
 0.18A 6nmpN-1qleA:
53.9		 6nmpN-1qleA:
53.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III
(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		4 / 7 HIS A 269
TRP A 323
TYR A 339
TRP C 106
 PC1  C 301 ( 4.2A)
None
PC1  C 301 (-3.3A)
PC1  C 301 (-4.4A)
 0.61A 6nmpN-1qleA:
53.9
6nmpP-1qleA:
2.5		 6nmpN-1qleA:
53.19
6nmpP-1qleA:
20.59