SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qlz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 1qlz PRION PROTEIN
(Homo
sapiens) 		3 / 3 GLN A 172
ILE A 215
TYR A 218
 None
 0.74A 1vifA-1qlzA:
undetectable		 1vifA-1qlzA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 1qlz PRION PROTEIN
(Homo
sapiens) 		4 / 6 TYR A 162
HIS A 187
THR A 190
VAL A 189
 None
 1.33A 3lb3B-1qlzA:
1.7		 3lb3B-1qlzA:
18.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1qlz PRION PROTEIN
(Homo
sapiens) 		5 / 8 TYR A 128
TYR A 162
ILE A 182
VAL A 189
THR A 190
 None
 1.14A 4ma7A-1qlzA:
14.5		 4ma7A-1qlzA:
88.60