SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qmn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		3 / 3 PHE A 387
LEU A 103
LEU A  99
 None
 0.58A 1mx1E-1qmnA:
undetectable		 1mx1E-1qmnA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		4 / 7 LEU A  61
LEU A 299
LEU A 306
GLY A  79
 None
 0.80A 1n13D-1qmnA:
undetectable
1n13E-1qmnA:
undetectable		 1n13D-1qmnA:
13.45
1n13E-1qmnA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		3 / 3 THR A 393
PRO A 395
PRO A 373
 None
 0.79A 2d55C-1qmnA:
undetectable		 2d55C-1qmnA:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		4 / 8 SER A 178
SER A 314
THR A 313
LEU A 304
 None
 1.14A 2v0zO-1qmnA:
undetectable		 2v0zO-1qmnA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		5 / 12 LEU A 306
LEU A 303
ALA A  34
PHE A  96
LEU A 103
 None
 1.23A 3b0wA-1qmnA:
0.0		 3b0wA-1qmnA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		5 / 12 ILE A 169
GLY A  67
ALA A  68
ILE A 308
VAL A 329
 None
 0.88A 4nkxB-1qmnA:
undetectable		 4nkxB-1qmnA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		6 / 12 THR A  59
ALA A  60
LEU A 184
LEU A 299
GLY A  79
LEU A  80
 None
 1.33A 4xi3B-1qmnA:
undetectable		 4xi3B-1qmnA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		6 / 12 THR A  59
ALA A  60
LEU A 184
LEU A 299
GLY A  79
LEU A  80
 None
 1.32A 4xi3C-1qmnA:
undetectable		 4xi3C-1qmnA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		3 / 3 THR A 238
HIS A 224
LEU A 226
 None
 0.85A 5axdC-1qmnA:
undetectable		 5axdC-1qmnA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		5 / 12 LEU A 184
SER A  53
TYR A 138
ASN A 116
HIS A  93
 None
 1.03A 5d0yA-1qmnA:
undetectable		 5d0yA-1qmnA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		5 / 12 LEU A 184
SER A  53
TYR A 138
ASN A 116
HIS A  93
 None
 1.04A 5d0yB-1qmnA:
0.0		 5d0yB-1qmnA:
19.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		5 / 9 VAL A  31
LEU A 272
ASP A 277
VAL A 379
ILE A 386
 None
 0.52A 5om2A-1qmnA:
37.4
5om2B-1qmnA:
undetectable		 5om2A-1qmnA:
85.00
5om2B-1qmnA:
9.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1qmn ALPHA-1-ANTICHYMOTRY
PSIN
(Homo
sapiens) 		4 / 6 LEU A  37
SER A  36
PHE A  33
ASP A  32
 None
 1.09A 5om3A-1qmnA:
37.0
5om3B-1qmnA:
0.0		 5om3A-1qmnA:
85.00
5om3B-1qmnA:
11.63