SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 12 GLY A  48
LEU A  31
VAL E 236
LEU A  88
ALA A  89
 None
 0.96A 1gseB-1qmoA:
undetectable		 1gseB-1qmoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 11 VAL A  33
VAL E 236
ASN E 234
GLU E 232
LEU A 106
 None
 1.32A 1t6zB-1qmoA:
undetectable		 1t6zB-1qmoA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus;
Lablab
purpureus) 		4 / 6 LEU A 106
GLY A 104
ASN E 144
ILE E 162
 None
MAN  A 302 (-3.7A)
MAN  A 302 ( 3.0A)
None
 0.89A 1xf1B-1qmoA:
undetectable		 1xf1B-1qmoA:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 12 ALA E 180
ILE A  72
VAL E 137
LEU A 108
ILE A  92
 None
 1.13A 1xozA-1qmoE:
undetectable		 1xozA-1qmoE:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 11 ALA E 180
ILE A  72
VAL E 137
LEU A 108
ILE A  92
 None
 1.13A 2h42A-1qmoE:
undetectable		 2h42A-1qmoE:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 12 ALA E 180
ILE A  72
VAL E 137
LEU A 108
ILE A  92
 None
 1.12A 2h42B-1qmoE:
undetectable		 2h42B-1qmoE:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 ASP A  17
SER A   7
PHE A   8
ASP A  12
 None
 1.22A 2obvA-1qmoA:
undetectable		 2obvA-1qmoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 ASP A  17
SER A   7
PHE A   8
ASP A  12
 None
 1.17A 2p02A-1qmoA:
undetectable		 2p02A-1qmoA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 8 ASP E 158
GLY E 156
ASP E 149
GLY A  87
LEU A  88
 None
None
MN  A 301 ( 2.4A)
None
None
 1.28A 3em6A-1qmoE:
undetectable		 3em6A-1qmoE:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 6 HIS E 154
VAL E 193
ILE E 162
LEU E 191
 MN  A 301 (-4.0A)
None
None
None
 0.80A 3kk6A-1qmoE:
undetectable		 3kk6A-1qmoE:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus;
Lablab
purpureus) 		3 / 3 TYR E 147
GLY A 104
ASP A  86
 None
MAN  A 302 (-3.7A)
MAN  A 302 (-3.2A)
 0.52A 3ou6C-1qmoE:
undetectable		 3ou6C-1qmoE:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 5 ILE E 182
THR E 194
SER E 195
PHE E 139
 None
 1.09A 3snfA-1qmoE:
undetectable		 3snfA-1qmoE:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 10 GLY A  87
GLY E 156
ILE E 155
PRO E 150
LEU E 143
 None
 0.89A 3ttpA-1qmoA:
undetectable		 3ttpA-1qmoA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		5 / 10 GLY A  87
GLY E 156
ILE E 155
PRO E 150
LEU E 143
 None
 0.88A 3ttpB-1qmoA:
undetectable		 3ttpB-1qmoA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus;
Lablab
purpureus) 		5 / 12 GLY A 103
GLY A 104
TYR E 147
ASN E 144
VAL A  43
 MAN  A 302 ( 3.8A)
MAN  A 302 (-3.7A)
None
MAN  A 302 ( 3.0A)
None
 1.08A 4fglA-1qmoA:
undetectable
4fglB-1qmoA:
undetectable		 4fglA-1qmoA:
19.63
4fglB-1qmoA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 SER A   5
SER A   7
SER E 240
THR E 242
 None
 0.74A 4ikjA-1qmoA:
undetectable
4ikjB-1qmoA:
undetectable		 4ikjA-1qmoA:
21.09
4ikjB-1qmoA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 SER E 240
THR E 242
SER A   5
SER A   7
 None
 0.79A 4ikkA-1qmoE:
undetectable
4ikkB-1qmoE:
undetectable		 4ikkA-1qmoE:
16.79
4ikkB-1qmoE:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus;
Lablab
purpureus) 		5 / 12 SER E 164
GLY E 156
ILE A  84
ALA A  85
GLY A  87
 MN  A 301 ( 3.7A)
None
None
MAN  A 302 ( 3.7A)
None
 1.07A 4r29D-1qmoE:
undetectable		 4r29D-1qmoE:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus;
Lablab
purpureus) 		5 / 12 GLY A 104
GLY A 103
GLY A  87
ILE E 155
TYR E 152
 MAN  A 302 (-3.7A)
MAN  A 302 ( 3.8A)
None
None
None
 1.04A 4rtmA-1qmoA:
undetectable		 4rtmA-1qmoA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus;
Lablab
purpureus) 		5 / 12 GLY A 104
GLY A 103
GLY A  87
TYR E 152
TYR E 147
 MAN  A 302 (-3.7A)
MAN  A 302 ( 3.8A)
None
None
None
 0.91A 4rtmA-1qmoA:
undetectable		 4rtmA-1qmoA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		3 / 3 SER E 132
GLU E 138
GLU E 232
 None
MN  A 301 (-3.1A)
None
 0.82A 4ymgB-1qmoE:
undetectable		 4ymgB-1qmoE:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 ASP A  17
SER A   7
PHE A   8
ASP A  12
 None
 1.18A 5a1iA-1qmoA:
undetectable		 5a1iA-1qmoA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 6 ASP E 230
TYR A  80
THR A  78
SER A  82
 None
 1.49A 5b6iB-1qmoE:
undetectable		 5b6iB-1qmoE:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus;
Lablab
purpureus) 		3 / 3 GLY A  87
THR E 227
ASN E 234
 None
 0.48A 5odiG-1qmoA:
undetectable		 5odiG-1qmoA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 ASP A  17
SER A   7
PHE A   8
ASP A  12
 None
 1.21A 6fboA-1qmoA:
undetectable		 6fboA-1qmoA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 ASP A  17
SER A   7
PHE A   8
ASP A  12
 None
 1.22A 6fcbA-1qmoA:
undetectable		 6fcbA-1qmoA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1qmo MANNOSE BINDING
LECTIN, FRIL
(Lablab
purpureus) 		4 / 8 ASP A  17
SER A   7
PHE A   8
ASP A  12
 None
 1.19A 6fcdA-1qmoA:
undetectable		 6fcdA-1qmoA:
23.36