SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 PRO A  44
THR A  48
CYH A  51
ARG A 127
 None
 0.51A 1h4oB-1qmvA:
18.6		 1h4oB-1qmvA:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 PRO A  44
THR A  48
CYH A  51
ARG A 127
 None
 0.53A 1h4oG-1qmvA:
18.4		 1h4oG-1qmvA:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 PRO A  44
THR A  48
CYH A  51
ARG A 127
 None
 0.53A 1oc3A-1qmvA:
18.4		 1oc3A-1qmvA:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2002_0
(TRYPTOPHAN
HALOGENASE)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		5 / 12 ILE A  55
PRO A  52
ILE A  87
HIS A  83
PHE A  41
 None
 1.35A 2oa1A-1qmvA:
1.8		 2oa1A-1qmvA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 6 ASP A 106
PHE A  42
ASP A 114
TYR A 115
 None
 1.28A 2todA-1qmvA:
0.0
2todB-1qmvA:
0.0		 2todA-1qmvA:
18.27
2todB-1qmvA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_B_DMOB700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 5 ASP A 114
TYR A 115
ASP A 106
PHE A  42
 None
 1.31A 2todA-1qmvA:
0.1
2todB-1qmvA:
0.0		 2todA-1qmvA:
18.27
2todB-1qmvA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_C_DMOC700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 5 ASP A 106
PHE A  42
ASP A 114
TYR A 115
 None
 1.31A 2todC-1qmvA:
0.0
2todD-1qmvA:
0.0		 2todC-1qmvA:
18.27
2todD-1qmvA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_D_DMOD700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 5 ASP A 114
TYR A 115
ASP A 106
PHE A  42
 None
 1.30A 2todC-1qmvA:
0.0
2todD-1qmvA:
0.0		 2todC-1qmvA:
18.27
2todD-1qmvA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		6 / 8 ALA A  17
GLU A  27
LEU A 104
LEU A  73
VAL A  38
ILE A 132
 None
 1.35A 2uxpA-1qmvA:
undetectable		 2uxpA-1qmvA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 PRO A  44
THR A  48
VAL A  50
ARG A 127
 None
 0.48A 2v32C-1qmvA:
22.2
2v32D-1qmvA:
23.4		 2v32C-1qmvA:
27.20
2v32D-1qmvA:
27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 PRO A  44
THR A  48
VAL A  50
ARG A 127
 None
 0.47A 2v41C-1qmvA:
23.5
2v41D-1qmvA:
23.4		 2v41C-1qmvA:
27.20
2v41D-1qmvA:
27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 PRO A  44
THR A  48
VAL A  50
ARG A 127
 None
 0.54A 2v41C-1qmvA:
23.5
2v41D-1qmvA:
23.5		 2v41C-1qmvA:
27.20
2v41D-1qmvA:
27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 PRO A  44
THR A  48
VAL A  50
ARG A 127
 None
 0.54A 2v41G-1qmvA:
22.0
2v41H-1qmvA:
22.1		 2v41G-1qmvA:
27.20
2v41H-1qmvA:
27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		5 / 9 LEU A  96
ASP A  46
SER A  59
ILE A 101
THR A  82
 None
 1.22A 3freX-1qmvA:
undetectable		 3freX-1qmvA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		4 / 8 LEU A  40
ILE A 141
PHE A  42
GLY A 116
 None
 0.79A 5eseA-1qmvA:
undetectable		 5eseA-1qmvA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		3 / 3 ARG A  91
ASN A 100
ASP A  64
 None
 0.85A 5gwxA-1qmvA:
undetectable		 5gwxA-1qmvA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 1qmv PEROXIREDOXIN-2
(Homo
sapiens) 		5 / 10 ALA A 155
THR A  53
PHE A  58
PHE A  41
VAL A  39
 None
 1.42A 6hu9C-1qmvA:
undetectable		 6hu9C-1qmvA:
19.54