SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		3 / 3 ILE A  56
LEU A  59
VAL A  63
 None
 0.36A 1mz9B-1qmyA:
undetectable		 1mz9B-1qmyA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		4 / 5 PRO A  66
PHE A  60
PHE A  67
ILE A 115
 None
 1.05A 2hjhA-1qmyA:
undetectable		 2hjhA-1qmyA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		5 / 11 GLY A 114
ILE A 115
ILE A 104
LEU A  59
VAL A  63
 None
 1.02A 2kawA-1qmyA:
undetectable		 2kawA-1qmyA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		4 / 7 ILE A  83
LEU A  86
VAL A 103
GLY A  98
 None
 0.63A 2wd9A-1qmyA:
undetectable		 2wd9A-1qmyA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		4 / 8 ILE A  83
LEU A  86
VAL A 103
GLY A  98
 None
 0.64A 2wd9B-1qmyA:
undetectable		 2wd9B-1qmyA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		5 / 12 PHE A  68
GLN A  85
HIS A 109
PHE A  60
LEU A  89
 None
 1.33A 3adxA-1qmyA:
undetectable		 3adxA-1qmyA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		5 / 12 LEU A  57
PHE A  68
ILE A  83
VAL A 124
VAL A 103
 None
 1.36A 3w1wA-1qmyA:
undetectable		 3w1wA-1qmyA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		5 / 12 LEU A  57
PHE A  68
ILE A  83
VAL A 124
VAL A 103
 None
 1.33A 3w1wB-1qmyA:
undetectable		 3w1wB-1qmyA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		4 / 5 PHE A 151
TYR A  62
THR A  40
ILE A 162
 None
 1.13A 4jx1E-1qmyA:
undetectable		 4jx1E-1qmyA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		4 / 7 ILE A  56
PHE A  60
VAL A 103
ILE A 107
 None
 0.96A 4zzbC-1qmyA:
undetectable
4zzbD-1qmyA:
undetectable		 4zzbC-1qmyA:
19.08
4zzbD-1qmyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		4 / 6 PRO A 172
LEU A 178
PHE A 180
LEU A  59
 None
 1.16A 5tl8A-1qmyA:
undetectable		 5tl8A-1qmyA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1qmy PROTEASE
(Foot-and-mouth
disease
virus) 		3 / 3 ASP A 164
ASN A  46
ASP A  49
 None
 0.84A 5vopB-1qmyA:
undetectable		 5vopB-1qmyA:
22.15