SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qnr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 6 PRO A 170
TRP A  56
GLU A 205
TRP A 114
 None
GOL  A 411 (-4.0A)
MAB  A 401 (-3.9A)
MAB  A 401 (-3.6A)
 1.30A 1ffyA-1qnrA:
0.3		 1ffyA-1qnrA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		5 / 12 GLU A 275
ILE A 107
LEU A 166
ASP A 236
LEU A 199
 None
 1.13A 1hvyD-1qnrA:
0.0		 1hvyD-1qnrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 5 PHE A  58
ILE A 107
PRO A 109
GLU A 165
 None
 1.50A 1oniG-1qnrA:
0.0
1oniH-1qnrA:
0.0		 1oniG-1qnrA:
17.63
1oniH-1qnrA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		3 / 3 GLU A 276
ASN A  25
TRP A  56
 GOL  A 410 (-3.8A)
None
GOL  A 411 (-4.0A)
 1.25A 1r15C-1qnrA:
2.0		 1r15C-1qnrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		3 / 3 GLU A 276
ASN A  25
TRP A  56
 GOL  A 410 (-3.8A)
None
GOL  A 411 (-4.0A)
 1.27A 1r15E-1qnrA:
0.0		 1r15E-1qnrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		3 / 3 GLU A 276
ASN A  25
TRP A  56
 GOL  A 410 (-3.8A)
None
GOL  A 411 (-4.0A)
 1.26A 1r15F-1qnrA:
2.0		 1r15F-1qnrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 5 ALA A 163
PHE A 162
ILE A   7
ASP A 236
 None
 1.13A 1yc2D-1qnrA:
undetectable		 1yc2D-1qnrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 GLN A 307
TYR A 243
TRP A  56
GLU A 169
 None
GOL  A 410 (-3.6A)
GOL  A 411 (-4.0A)
MAB  A 401 ( 2.8A)
 1.23A 2aowA-1qnrA:
undetectable		 2aowA-1qnrA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 VAL A  52
LEU A 106
HIS A 198
ASP A  15
 None
 1.01A 2ddwA-1qnrA:
undetectable		 2ddwA-1qnrA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		6 / 12 ASN A 168
GLU A 169
HIS A 241
TYR A 243
GLU A 276
TRP A 306
 None
MAB  A 401 ( 2.8A)
None
GOL  A 410 (-3.6A)
GOL  A 410 (-3.8A)
GOL  A 410 (-3.6A)
 0.95A 2v3dA-1qnrA:
6.1		 2v3dA-1qnrA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		5 / 10 ILE A 180
VAL A 179
TYR A 144
VAL A 111
LEU A 235
 None
 1.19A 3em0A-1qnrA:
undetectable		 3em0A-1qnrA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 4 PRO A 244
THR A 249
GLY A 212
THR A 211
 None
 1.12A 3ib1A-1qnrA:
undetectable		 3ib1A-1qnrA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 GLU A 222
LEU A 202
TRP A 183
ASN A 229
 None
 1.42A 3k8mB-1qnrA:
11.4		 3k8mB-1qnrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 GLY A 254
PHE A 237
PHE A 240
PHE A 226
 None
 0.60A 3ko0D-1qnrA:
undetectable
3ko0E-1qnrA:
undetectable		 3ko0D-1qnrA:
13.95
3ko0E-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 GLY A 256
PHE A 237
PHE A 240
PHE A 226
 None
 1.02A 3ko0D-1qnrA:
undetectable
3ko0E-1qnrA:
undetectable		 3ko0D-1qnrA:
13.95
3ko0E-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 PHE A 240
PHE A 226
GLY A 254
PHE A 237
 None
 0.71A 3ko0B-1qnrA:
undetectable
3ko0J-1qnrA:
undetectable		 3ko0B-1qnrA:
13.95
3ko0J-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 GLY A 254
PHE A 237
PHE A 240
PHE A 226
 None
 0.62A 3ko0L-1qnrA:
undetectable
3ko0N-1qnrA:
undetectable		 3ko0L-1qnrA:
13.95
3ko0N-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 GLY A 256
PHE A 237
PHE A 240
PHE A 226
 None
 1.13A 3ko0L-1qnrA:
undetectable
3ko0N-1qnrA:
undetectable		 3ko0L-1qnrA:
13.95
3ko0N-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 GLY A 254
PHE A 237
PHE A 240
PHE A 226
 None
 0.73A 3ko0M-1qnrA:
undetectable
3ko0P-1qnrA:
undetectable		 3ko0M-1qnrA:
13.95
3ko0P-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 GLY A 254
PHE A 237
PHE A 240
PHE A 226
 None
 0.65A 3ko0O-1qnrA:
undetectable
3ko0Q-1qnrA:
undetectable		 3ko0O-1qnrA:
13.95
3ko0Q-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 PHE A 240
PHE A 226
GLY A 254
PHE A 237
 None
 0.70A 3ko0K-1qnrA:
undetectable
3ko0S-1qnrA:
undetectable		 3ko0K-1qnrA:
13.95
3ko0S-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 PHE A 240
PHE A 226
GLY A 254
PHE A 237
 None
 0.62A 3ko0R-1qnrA:
undetectable
3ko0T-1qnrA:
undetectable		 3ko0R-1qnrA:
13.95
3ko0T-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 7 PHE A 240
PHE A 226
GLY A 256
PHE A 237
 None
 1.07A 3ko0R-1qnrA:
undetectable
3ko0T-1qnrA:
undetectable		 3ko0R-1qnrA:
13.95
3ko0T-1qnrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 6 GLY A 309
TRP A 326
ASP A 310
THR A  41
 None
 1.15A 3vqrA-1qnrA:
undetectable		 3vqrA-1qnrA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 SER A 294
ILE A  14
VAL A   5
PHE A  12
 None
 0.98A 4dx7B-1qnrA:
undetectable		 4dx7B-1qnrA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		5 / 12 GLU A 275
ILE A 107
LEU A 166
ASP A 236
LEU A 199
 None
 1.17A 4foxA-1qnrA:
0.0		 4foxA-1qnrA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		5 / 12 GLU A 275
ILE A 107
LEU A 166
ASP A 236
LEU A 199
 None
 1.19A 4foxB-1qnrA:
0.0		 4foxB-1qnrA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		5 / 12 GLU A 275
ILE A 107
LEU A 166
ASP A 236
LEU A 199
 None
 1.11A 4foxG-1qnrA:
0.0		 4foxG-1qnrA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		3 / 3 TYR A 117
GLN A 307
TRP A 114
 None
None
MAB  A 401 (-3.6A)
 0.93A 4kn2C-1qnrA:
0.0		 4kn2C-1qnrA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 VAL A 151
LEU A  89
ILE A  70
VAL A  61
 None
 0.90A 4ma7A-1qnrA:
undetectable		 4ma7A-1qnrA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 6 ASN A 168
GLU A 165
GLU A 169
GLU A 205
 None
None
MAB  A 401 ( 2.8A)
MAB  A 401 (-3.9A)
 1.43A 4mi4A-1qnrA:
0.9		 4mi4A-1qnrA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		5 / 12 GLY A 119
PHE A 110
ASN A 113
ALA A 122
ASN A 125
 None
 1.34A 4pclB-1qnrA:
2.3		 4pclB-1qnrA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 ARG A 171
GLU A 205
PRO A 217
GLY A 208
 MAB  A 401 (-2.7A)
MAB  A 401 (-3.9A)
None
None
 1.11A 5kgpB-1qnrA:
1.1		 5kgpB-1qnrA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		5 / 12 ILE A   7
PHE A  21
GLY A 301
HIS A 241
MET A 304
 None
 1.24A 6e8qA-1qnrA:
undetectable		 6e8qA-1qnrA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 5 PHE A 240
VAL A  52
PRO A 271
MET A 300
 None
 1.22A 6ekzA-1qnrA:
undetectable		 6ekzA-1qnrA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 1qnr ENDO-1,4-B-D-MANNANA
SE
(Trichoderma
reesei) 		4 / 8 VAL A 111
TYR A 144
TYR A 135
GLU A 205
 None
None
None
MAB  A 401 (-3.9A)
 1.28A 6gneB-1qnrA:
2.5		 6gneB-1qnrA:
20.73