SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 5 LEU A 142
PRO A 138
VAL A 139
ILE A 143
 None
 0.84A 2aoiB-1qntA:
undetectable		 2aoiB-1qntA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 5 ILE A  76
PRO A  73
PHE A  70
ILE A 141
 None
 1.01A 2hjhA-1qntA:
undetectable		 2hjhA-1qntA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 7 ARG A 128
ASN A 157
GLY A 156
VAL A 148
 None
 0.93A 2y05A-1qntA:
undetectable
2y05B-1qntA:
undetectable		 2y05A-1qntA:
21.23
2y05B-1qntA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 9 ALA A 118
ALA A 121
GLY A 131
GLY A 132
ALA A 129
 None
 1.05A 4qvmK-1qntA:
undetectable
4qvmL-1qntA:
undetectable		 4qvmK-1qntA:
22.94
4qvmL-1qntA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 ALA A 118
ALA A 121
GLY A 131
GLY A 132
ALA A 129
 None
 1.04A 4qw1Y-1qntA:
undetectable
4qw1Z-1qntA:
undetectable		 4qw1Y-1qntA:
23.38
4qw1Z-1qntA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 ALA A 118
ALA A 121
GLY A 131
GLY A 132
ALA A 129
 None
 1.05A 4qw3K-1qntA:
undetectable
4qw3L-1qntA:
undetectable		 4qw3K-1qntA:
22.08
4qw3L-1qntA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 ALA A 118
ALA A 121
GLY A 131
GLY A 132
ALA A 129
 None
 1.05A 4qw3Y-1qntA:
undetectable
4qw3Z-1qntA:
undetectable		 4qw3Y-1qntA:
22.08
4qw3Z-1qntA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 9 ALA A 118
ALA A 121
GLY A 131
GLY A 132
ALA A 129
 None
 1.06A 5d0xK-1qntA:
undetectable
5d0xL-1qntA:
undetectable		 5d0xK-1qntA:
22.94
5d0xL-1qntA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 9 ALA A 118
ALA A 121
GLY A 131
GLY A 132
ALA A 129
 None
 1.06A 5d0xY-1qntA:
undetectable
5d0xZ-1qntA:
undetectable		 5d0xY-1qntA:
22.94
5d0xZ-1qntA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 ALA A  68
LEU A  66
LEU A 142
ALA A  75
PRO A  82
 None
 0.98A 5jglA-1qntA:
undetectable		 5jglA-1qntA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1qnt METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 8 ALA A  64
LEU A  28
LEU A 142
LEU A  12
LEU A  21
 None
 1.37A 5jqbA-1qntA:
undetectable
5jqbB-1qntA:
undetectable		 5jqbA-1qntA:
18.71
5jqbB-1qntA:
20.86