SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qnz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1qnz 0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus) 		3 / 3 ASP L  86
LEU L 108
GLN L   6
 None
 0.66A 3g4lA-1qnzL:
undetectable		 3g4lA-1qnzL:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1qnz 0.5B ANTIBODY (HEAVY
CHAIN)
0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus;
Mus
musculus) 		3 / 3 ASN L  96
MET H 218
PHE L 100
 None
 0.91A 3g4lD-1qnzL:
undetectable		 3g4lD-1qnzL:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 1qnz 0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus) 		5 / 8 GLY L 103
TYR L  90
ALA L   9
SER L 104
TYR L  91
 None
 1.10A 4bjcA-1qnzL:
undetectable		 4bjcA-1qnzL:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 1qnz 0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus) 		5 / 8 GLY L 103
TYR L  90
ALA L   9
SER L 104
TYR L  91
 None
 1.13A 4hyfB-1qnzL:
undetectable		 4hyfB-1qnzL:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 1qnz 0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus) 		5 / 11 GLY L 103
TYR L  90
ALA L   9
SER L 104
TYR L  91
 None
 1.10A 4rv6A-1qnzL:
undetectable		 4rv6A-1qnzL:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 1qnz 0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus) 		5 / 11 GLY L 103
TYR L  90
ALA L   9
SER L 104
TYR L  91
 None
 1.09A 4rv6B-1qnzL:
undetectable		 4rv6B-1qnzL:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1qnz 0.5B ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 4 TYR H 172
THR H 170
GLY H 161
LEU H 193
 None
 1.42A 4w5nA-1qnzH:
undetectable		 4w5nA-1qnzH:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1qnz 0.5B ANTIBODY (HEAVY
CHAIN)
0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus;
Mus
musculus) 		4 / 6 LEU L  50
TRP H 148
GLN H 118
MET H 149
 None
 1.41A 5h8tA-1qnzL:
0.0		 5h8tA-1qnzL:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 1qnz 0.5B ANTIBODY (LIGHT
CHAIN)
(Mus
musculus) 		3 / 3 GLN L  94
THR L 101
ASP L   1
 None
 0.81A 5k9dA-1qnzL:
undetectable		 5k9dA-1qnzL:
14.60