SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qo4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 8 HIS A 169
GLY A 172
LEU A 243
ASP A 246
 HEM  A 374 (-3.5A)
HEM  A 374 (-3.4A)
None
None
 0.45A 1aegA-1qo4A:
24.2		 1aegA-1qo4A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 4 GLY A  33
SER A  35
VAL A  79
LEU A  26
 None
HEM  A 374 (-2.8A)
None
None
 1.32A 1yajB-1qo4A:
undetectable		 1yajB-1qo4A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 6 VAL A  80
LEU A 288
ILE A 285
ALA A  51
LEU A  54
 None
 1.42A 3kk6B-1qo4A:
undetectable		 3kk6B-1qo4A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 10 ILE A 138
ARG A 123
ALA A 102
LEU A 101
ALA A  51
 None
 1.42A 3lw5B-1qo4A:
undetectable		 3lw5B-1qo4A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 5 THR A 149
ILE A 148
GLU A 143
PHE A  41
 None
HEM  A 374 ( 4.7A)
None
HEM  A 374 (-3.6A)
 1.30A 4ac9C-1qo4A:
undetectable		 4ac9C-1qo4A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 5 THR A 149
ILE A 148
GLU A 143
PHE A  45
 None
HEM  A 374 ( 4.7A)
None
None
 1.48A 4ac9C-1qo4A:
undetectable		 4ac9C-1qo4A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 5 THR A 149
ILE A 148
GLU A 143
PHE A  45
 None
HEM  A 374 ( 4.7A)
None
None
 1.45A 4acaC-1qo4A:
undetectable		 4acaC-1qo4A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 5 THR A 149
ILE A 148
GLU A 143
PHE A  41
 None
HEM  A 374 ( 4.7A)
None
HEM  A 374 (-3.6A)
 1.31A 4acbC-1qo4A:
undetectable		 4acbC-1qo4A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 5 THR A 149
ILE A 148
GLU A 143
PHE A  45
 None
HEM  A 374 ( 4.7A)
None
None
 1.46A 4acbC-1qo4A:
undetectable		 4acbC-1qo4A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 142
LEU A 145
ASP A 246
LEU A 243
TYR A 232
 None
 1.18A 4foxA-1qo4A:
0.2		 4foxA-1qo4A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 142
LEU A 145
ASP A 246
LEU A 243
TYR A 232
 None
 1.22A 4foxB-1qo4A:
0.1		 4foxB-1qo4A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 142
LEU A 145
ASP A 246
LEU A 243
TYR A 232
 None
 1.17A 4foxG-1qo4A:
0.2		 4foxG-1qo4A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 5 PHE A 233
HIS A 169
LEU A 243
PRO A 141
 None
HEM  A 374 (-3.5A)
None
HEM  A 374 (-3.9A)
 1.40A 4o8zA-1qo4A:
undetectable		 4o8zA-1qo4A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 12 ILE A  53
ALA A  74
THR A  21
VAL A  18
LEU A 101
 None
 1.21A 4qynA-1qo4A:
0.0		 4qynA-1qo4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 12 ILE A  53
ALA A  74
THR A  21
VAL A  18
LEU A 101
 None
 1.25A 4qzuA-1qo4A:
undetectable		 4qzuA-1qo4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 7 THR A 159
LEU A 162
THR A 252
THR A 149
 None
 0.85A 4z90A-1qo4A:
undetectable
4z90B-1qo4A:
undetectable
4z90C-1qo4A:
undetectable
4z90D-1qo4A:
undetectable
4z90E-1qo4A:
undetectable		 4z90A-1qo4A:
19.46
4z90B-1qo4A:
19.46
4z90C-1qo4A:
19.46
4z90D-1qo4A:
19.46
4z90E-1qo4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 7 THR A 159
LEU A 162
THR A 252
THR A 149
 None
 0.84A 4z91F-1qo4A:
undetectable
4z91G-1qo4A:
undetectable
4z91H-1qo4A:
undetectable
4z91I-1qo4A:
undetectable
4z91J-1qo4A:
undetectable		 4z91F-1qo4A:
19.46
4z91G-1qo4A:
19.46
4z91H-1qo4A:
19.46
4z91I-1qo4A:
19.46
4z91J-1qo4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 7 THR A 252
THR A 149
THR A 159
LEU A 162
 None
 0.91A 4z91F-1qo4A:
undetectable
4z91G-1qo4A:
undetectable
4z91H-1qo4A:
undetectable
4z91I-1qo4A:
undetectable
4z91J-1qo4A:
undetectable		 4z91F-1qo4A:
19.46
4z91G-1qo4A:
19.46
4z91H-1qo4A:
19.46
4z91I-1qo4A:
19.46
4z91J-1qo4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		4 / 8 TYR A   7
ARG A 123
LEU A  87
ILE A 295
 None
 0.92A 5v0vA-1qo4A:
undetectable		 5v0vA-1qo4A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		5 / 12 ALA A 164
GLY A 167
SER A 166
LEU A 249
ASP A 221
 None
None
HEM  A 374 ( 3.9A)
None
CA  A 376 (-3.4A)
 1.45A 5vlmF-1qo4A:
0.0		 5vlmF-1qo4A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1qo4 PEROXIDASE
(Arabidopsis
thaliana) 		3 / 3 LEU A 183
ASN A 219
LEU A 243
 None
 0.70A 6exiA-1qo4A:
undetectable		 6exiA-1qo4A:
14.08