SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qoi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 1qoi SNUCYP-20
(Homo
sapiens) 		3 / 3 THR A 159
PRO A 161
PRO A 165
 None
 0.84A 2d55C-1qoiA:
undetectable		 2d55C-1qoiA:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 1qoi SNUCYP-20
(Homo
sapiens) 		3 / 3 TYR A  60
GLY A  62
PHE A  79
 None
 0.68A 2m2pB-1qoiA:
undetectable		 2m2pB-1qoiA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 1qoi SNUCYP-20
(Homo
sapiens) 		5 / 12 LEU A 109
GLY A 108
MET A 151
ILE A 154
VAL A  17
 None
 1.33A 4okwA-1qoiA:
undetectable		 4okwA-1qoiA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 1qoi SNUCYP-20
(Homo
sapiens) 		5 / 11 VAL A 170
ILE A 171
ILE A 144
ILE A  29
PHE A 124
 None
 1.18A 5hw8D-1qoiA:
undetectable		 5hw8D-1qoiA:
20.99