SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qor'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 6 LEU A 259
ILE A 252
GLU A 223
ASP A 227
 None
 1.06A 1ditH-1qorA:
0.0
1ditP-1qorA:
undetectable		 1ditH-1qorA:
20.82
1ditP-1qorA:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 HIS A 311
ILE A  43
ILE A  47
ALA A  94
TYR A  95
 None
SO4  A 328 (-3.6A)
None
None
None
 1.38A 1ki7A-1qorA:
undetectable		 1ki7A-1qorA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 6 LEU A  57
LEU A  92
GLY A  93
ARG A   4
 None
 0.69A 1mt1G-1qorA:
undetectable
1mt1J-1qorA:
undetectable		 1mt1G-1qorA:
13.96
1mt1J-1qorA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 7 ARG A   4
LEU A  57
LEU A  92
GLY A  93
 None
 0.69A 1mt1H-1qorA:
undetectable
1mt1K-1qorA:
undetectable		 1mt1H-1qorA:
17.93
1mt1K-1qorA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 7 ARG A   4
LEU A  57
LEU A  92
GLY A  93
 None
 0.68A 1n13D-1qorA:
undetectable
1n13E-1qorA:
undetectable		 1n13D-1qorA:
17.93
1n13E-1qorA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 8 LEU A  57
LEU A  92
GLY A  93
ARG A   4
 None
 0.66A 1n13A-1qorA:
undetectable
1n13F-1qorA:
undetectable		 1n13A-1qorA:
13.96
1n13F-1qorA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 6 ARG A   4
LEU A  57
LEU A  92
GLY A  93
 None
 0.64A 1n13H-1qorA:
undetectable
1n13K-1qorA:
undetectable		 1n13H-1qorA:
17.93
1n13K-1qorA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 7 LEU A  57
LEU A  92
GLY A  93
ARG A   4
 None
 0.67A 1n13G-1qorA:
undetectable
1n13J-1qorA:
undetectable		 1n13G-1qorA:
13.96
1n13J-1qorA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 ILE A 101
ALA A 119
GLY A  62
SER A  96
LEU A  92
 None
 1.05A 1rjdA-1qorA:
undetectable		 1rjdA-1qorA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 ILE A 101
ALA A 119
GLY A  62
SER A  96
LEU A  92
 None
 1.07A 1rjdB-1qorA:
4.9		 1rjdB-1qorA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 ILE A 101
ALA A 119
GLY A  62
SER A  96
LEU A  92
 None
 1.10A 1rjdC-1qorA:
4.8		 1rjdC-1qorA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 GLY A 170
VAL A 210
LEU A 197
LEU A 201
LEU A 229
 None
 1.15A 1ya4B-1qorA:
undetectable		 1ya4B-1qorA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 8 ARG A   4
LEU A  57
LEU A  92
GLY A  93
 None
 0.72A 2qqcH-1qorA:
undetectable
2qqcK-1qorA:
undetectable		 2qqcH-1qorA:
18.15
2qqcK-1qorA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 8 ARG A   4
LEU A  57
LEU A  92
GLY A  93
 None
 0.61A 2qqdB-1qorA:
undetectable
2qqdC-1qorA:
undetectable		 2qqdB-1qorA:
18.15
2qqdC-1qorA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 GLY A  62
GLY A  39
LEU A 325
HIS A 311
ILE A  40
 None
 1.22A 2y7kD-1qorA:
undetectable		 2y7kD-1qorA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 ILE A  40
GLY A  39
GLY A  62
LEU A  61
HIS A 311
 None
 1.11A 2y7kD-1qorA:
undetectable		 2y7kD-1qorA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 SER A  90
PHE A 284
ILE A 287
LEU A 325
ASP A  44
 None
 1.35A 3aocC-1qorA:
0.0		 3aocC-1qorA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 7 GLU A 298
LEU A 324
PRO A 327
ILE A 326
 None
 0.90A 3s56B-1qorA:
undetectable		 3s56B-1qorA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		3 / 3 PHE A  21
SER A  97
SER A  96
 None
 0.87A 3ufgB-1qorA:
undetectable		 3ufgB-1qorA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 SER A  59
LEU A  57
VAL A  19
ILE A  43
LEU A  16
 None
None
None
SO4  A 328 (-3.6A)
None
 1.04A 3w67B-1qorA:
undetectable		 3w67B-1qorA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_A_VK3A202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 5 ARG A 263
TYR A  46
TYR A  52
LEU A  51
 SO4  A 328 ( 2.9A)
NDP  A 350 ( 4.1A)
SO4  A 328 (-4.9A)
None
 1.46A 4f8yA-1qorA:
0.0
4f8yB-1qorA:
0.0		 4f8yA-1qorA:
20.18
4f8yB-1qorA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 5 ARG A 263
TYR A  46
TYR A  52
LEU A  51
 SO4  A 328 ( 2.9A)
NDP  A 350 ( 4.1A)
SO4  A 328 (-4.9A)
None
 1.42A 4f8yC-1qorA:
2.7
4f8yD-1qorA:
0.0		 4f8yC-1qorA:
20.18
4f8yD-1qorA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 7 TYR A  87
VAL A  69
ILE A  79
ILE A 108
ALA A 107
 None
 1.09A 4lv9A-1qorA:
undetectable		 4lv9A-1qorA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		3 / 3 PRO A 110
LEU A 109
GLN A 117
 None
 0.70A 4pevB-1qorA:
3.3		 4pevB-1qorA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 8 LEU A  92
GLY A  93
GLU A  30
ALA A  24
 None
 0.74A 4rjdA-1qorA:
0.0
4rjdB-1qorA:
0.0		 4rjdA-1qorA:
12.29
4rjdB-1qorA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 4 SER A 241
ASP A 220
ASP A 196
ASP A 215
 NDP  A 350 (-2.6A)
None
None
None
 1.36A 4uciA-1qorA:
0.6		 4uciA-1qorA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 4 SER A 241
ASP A 220
ASP A 196
ASP A 215
 NDP  A 350 (-2.6A)
None
None
None
 1.36A 4uciB-1qorA:
0.8		 4uciB-1qorA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 7 ALA A 107
ILE A 113
LEU A 283
PHE A 284
 None
 1.09A 4uymA-1qorA:
0.0		 4uymA-1qorA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 TYR A  95
GLU A 312
GLY A  12
LEU A 304
ALA A  18
 None
 1.27A 4wcxC-1qorA:
2.4		 4wcxC-1qorA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 TYR A  95
GLU A 312
LEU A 325
LEU A 304
ALA A  18
 None
 1.24A 4wcxC-1qorA:
2.4		 4wcxC-1qorA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		3 / 3 ASP A 220
GLY A 218
ASP A 215
 None
 0.67A 4xdtA-1qorA:
0.0		 4xdtA-1qorA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 7 ILE A  40
HIS A 311
LEU A 325
GLY A  62
 None
 1.00A 4z69A-1qorA:
0.0		 4z69A-1qorA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		5 / 12 ILE A 156
GLY A 125
THR A 127
PHE A 144
LEU A 155
 None
None
NDP  A 350 (-3.0A)
None
None
 1.11A 5hw4C-1qorA:
2.8		 5hw4C-1qorA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		3 / 3 TYR A 129
SER A 280
TRP A 160
 None
 1.05A 5n8jB-1qorA:
undetectable		 5n8jB-1qorA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 7 HIS A  78
ILE A  79
SER A 280
THR A 277
 None
 1.07A 5vkqA-1qorA:
0.0
5vkqD-1qorA:
0.0		 5vkqA-1qorA:
11.73
5vkqD-1qorA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1qor QUINONE
OXIDOREDUCTASE
(Escherichia
coli) 		4 / 5 VAL A 128
LEU A 283
VAL A  86
LEU A 276
 None
 0.91A 6bqgA-1qorA:
undetectable		 6bqgA-1qorA:
11.80