SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qot'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 GLN A  23
GLY A 217
GLY A 216
ALA A  26
LEU A  34
 None
 0.98A 1bx4A-1qotA:
undetectable		 1bx4A-1qotA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 TRP A 160
VAL A 167
TRP A 162
 None
 1.33A 1c4dC-1qotA:
undetectable
1c4dD-1qotA:
undetectable		 1c4dC-1qotA:
5.58
1c4dD-1qotA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 6 HIS A 227
GLY A 217
ALA A  89
GLU A 126
 None
None
None
MN  A 301 (-2.5A)
 0.70A 1dmaB-1qotA:
undetectable		 1dmaB-1qotA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 10 VAL A 200
PHE A  73
VAL A 170
ILE A  58
LEU A 181
 None
 1.21A 1fe2A-1qotA:
undetectable		 1fe2A-1qotA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 9 THR A 129
GLY A  84
GLY A 217
GLU A 225
GLY A 219
 None
None
None
None
GAL  A 502 (-3.6A)
 1.26A 1jhoA-1qotA:
undetectable		 1jhoA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 9 THR A 129
GLY A  84
GLY A 217
GLU A 225
GLY A 219
 None
None
None
None
GAL  A 502 (-3.6A)
 1.25A 1jhrA-1qotA:
undetectable		 1jhrA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 9 THR A 129
GLY A  84
GLY A 217
GLU A 225
GLY A 219
 None
None
None
None
GAL  A 502 (-3.6A)
 1.26A 1l5kA-1qotA:
undetectable		 1l5kA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 9 THR A 129
GLY A  84
GLY A 217
GLU A 225
GLY A 219
 None
None
None
None
GAL  A 502 (-3.6A)
 1.25A 1l5lA-1qotA:
undetectable		 1l5lA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 9 THR A 129
GLY A  84
GLY A 217
GLU A 225
GLY A 219
 None
None
None
None
GAL  A 502 (-3.6A)
 1.26A 1l5mA-1qotA:
undetectable		 1l5mA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 ALA A  54
VAL A 210
TRP A 209
 None
 0.91A 1ng8A-1qotA:
undetectable		 1ng8A-1qotA:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 ALA A  54
VAL A 210
TRP A 209
 None
 0.91A 1ng8B-1qotA:
undetectable		 1ng8B-1qotA:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 LEU A 230
GLU A 166
GLY A 165
SER A 189
ASP A  80
 None
 1.29A 2bm9B-1qotA:
undetectable		 2bm9B-1qotA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 GLY A 106
PHE A 127
GLY A 216
GLY A 217
PHE A  90
 FUC  A 501 (-3.7A)
None
None
None
None
 1.16A 2dpmA-1qotA:
undetectable		 2dpmA-1qotA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 PHE A 127
GLY A  87
ILE A 145
LEU A 185
VAL A  36
 None
 0.93A 2hmyB-1qotA:
undetectable		 2hmyB-1qotA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 ASP A 128
TYR A 130
LYS A 133
 CA  A 302 ( 2.3A)
GAL  A 502 (-3.6A)
None
 1.18A 2othA-1qotA:
undetectable		 2othA-1qotA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 TRP A 160
VAL A 167
TRP A 162
 None
 1.15A 2xdcC-1qotA:
undetectable
2xdcD-1qotA:
undetectable		 2xdcC-1qotA:
5.58
2xdcD-1qotA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 TRP A 160
VAL A 167
TRP A 162
 None
 1.16A 2xdcE-1qotA:
undetectable
2xdcF-1qotA:
undetectable		 2xdcE-1qotA:
5.58
2xdcF-1qotA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 TRP A 160
VAL A 167
TRP A 162
 None
 1.17A 2y5mE-1qotA:
undetectable
2y5mF-1qotA:
undetectable		 2y5mE-1qotA:
5.58
2y5mF-1qotA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 TRP A 160
VAL A 167
TRP A 162
 None
 1.18A 2y6nC-1qotA:
undetectable
2y6nD-1qotA:
undetectable		 2y6nC-1qotA:
5.58
2y6nD-1qotA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 TRP A 160
VAL A 167
TRP A 162
 None
 1.17A 2y6nE-1qotA:
undetectable
2y6nF-1qotA:
undetectable		 2y6nE-1qotA:
5.58
2y6nF-1qotA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 7 ALA A  70
SER A  68
THR A 173
VAL A 171
 None
 0.94A 3d2tA-1qotA:
undetectable		 3d2tA-1qotA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 6 ALA A  70
SER A  68
THR A 173
VAL A 171
 None
 1.05A 3d2tB-1qotA:
0.0		 3d2tB-1qotA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 6 ILE A 147
THR A  71
PHE A  73
PHE A 127
 None
 1.30A 3elzB-1qotA:
0.0		 3elzB-1qotA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 5 ILE A 123
THR A  71
PHE A  73
PHE A 127
 None
 1.27A 3em0A-1qotA:
1.0		 3em0A-1qotA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 6 HIS A 144
VAL A 183
ILE A 152
LEU A 181
 MN  A 301 (-3.3A)
None
None
None
 0.83A 3kk6A-1qotA:
undetectable		 3kk6A-1qotA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 4 LEU A  88
GLY A  87
GLY A 216
THR A  37
 None
 0.63A 3si7A-1qotA:
undetectable		 3si7A-1qotA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 5 LEU A  88
GLY A  87
GLY A 216
THR A  37
 None
 0.65A 3si7C-1qotA:
undetectable
3si7D-1qotA:
undetectable		 3si7C-1qotA:
21.28
3si7D-1qotA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 8 HIS A 227
GLY A 217
ALA A  89
GLU A 126
 None
None
None
MN  A 301 (-2.5A)
 0.84A 3u9hA-1qotA:
undetectable		 3u9hA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 8 HIS A 227
GLY A 217
ALA A  89
GLU A 126
 None
None
None
MN  A 301 (-2.5A)
 0.79A 3u9hB-1qotA:
undetectable		 3u9hB-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		3 / 3 TRP A 160
VAL A 167
TRP A 162
 None
 1.36A 3zq8A-1qotA:
undetectable
3zq8B-1qotA:
undetectable		 3zq8A-1qotA:
5.58
3zq8B-1qotA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 8 HIS A 227
GLY A 217
ALA A  89
GLU A 126
 None
None
None
MN  A 301 (-2.5A)
 0.83A 4bjcA-1qotA:
undetectable		 4bjcA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 7 HIS A 227
GLY A 217
ALA A  89
GLU A 126
 None
None
None
MN  A 301 (-2.5A)
 0.72A 4hyfA-1qotA:
undetectable		 4hyfA-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 8 HIS A 227
GLY A 217
ALA A  89
GLU A 126
 None
None
None
MN  A 301 (-2.5A)
 0.70A 4hyfB-1qotA:
undetectable		 4hyfB-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		4 / 8 HIS A 227
GLY A 217
ALA A  89
GLU A 126
 None
None
None
MN  A 301 (-2.5A)
 0.68A 4hyfC-1qotA:
undetectable		 4hyfC-1qotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 ILE A 152
HIS A 144
SER A 103
GLY A 106
GLY A 109
 None
MN  A 301 (-3.3A)
None
FUC  A 501 (-3.7A)
None
 1.15A 5nnaA-1qotA:
undetectable		 5nnaA-1qotA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 ILE A 152
HIS A 144
SER A 103
GLY A 106
GLY A 109
 None
MN  A 301 (-3.3A)
None
FUC  A 501 (-3.7A)
None
 1.15A 5nnaB-1qotA:
undetectable		 5nnaB-1qotA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 ILE A 152
HIS A 144
SER A 103
GLY A 106
GLY A 109
 None
MN  A 301 (-3.3A)
None
FUC  A 501 (-3.7A)
None
 1.15A 5nnaC-1qotA:
undetectable		 5nnaC-1qotA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 1qot CHITIN BINDING
LECTIN, UEA-II
(Ulex
europaeus) 		5 / 12 ILE A 152
HIS A 144
SER A 103
GLY A 106
GLY A 109
 None
MN  A 301 (-3.3A)
None
FUC  A 501 (-3.7A)
None
 1.17A 5nnaD-1qotA:
undetectable		 5nnaD-1qotA:
22.14