SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1qou CEN
(Antirrhinum
majus) 		5 / 11 ALA A 166
PHE A 122
PHE A 125
LEU A  66
VAL A  16
 None
 1.15A 1ukbA-1qouA:
undetectable		 1ukbA-1qouA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1qou CEN
(Antirrhinum
majus) 		4 / 6 PHE A  42
LEU A  41
PRO A  43
SER A  44
 None
 1.36A 3vlnA-1qouA:
undetectable		 3vlnA-1qouA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 1qou CEN
(Antirrhinum
majus) 		5 / 12 ALA A 166
ASP A  14
ILE A  12
ARG A 119
ILE A  67
 None
 1.00A 4m2xA-1qouA:
undetectable		 4m2xA-1qouA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 1qou CEN
(Antirrhinum
majus) 		5 / 12 ALA A 166
ASP A  14
ILE A  12
ARG A 119
ILE A  67
 None
 1.01A 4m2xE-1qouA:
undetectable		 4m2xE-1qouA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1qou CEN
(Antirrhinum
majus) 		4 / 7 VAL A  46
PHE A 120
HIS A 118
GLU A  40
 None
 1.43A 5ad9A-1qouA:
undetectable
5ad9B-1qouA:
undetectable		 5ad9A-1qouA:
17.40
5ad9B-1qouA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 1qou CEN
(Antirrhinum
majus) 		5 / 12 VAL A  35
GLY A  38
PHE A 169
VAL A  15
LEU A 123
 None
 0.81A 5ergB-1qouA:
undetectable		 5ergB-1qouA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 1qou CEN
(Antirrhinum
majus) 		5 / 12 VAL A  35
GLY A  38
PHE A 169
VAL A  16
LEU A 123
 None
 1.10A 5ergB-1qouA:
undetectable		 5ergB-1qouA:
19.52