SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qox'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 12 LEU A 104
TYR A 100
LEU A  68
LEU A 404
TYR A  76
 None
 1.22A 1p33A-1qoxA:
undetectable		 1p33A-1qoxA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 7 TYR A 378
HIS A 382
LEU A 335
TYR A 296
 None
 1.16A 1tuvA-1qoxA:
undetectable		 1tuvA-1qoxA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 ASP A 235
TYR A 229
GLU A 315
 None
 0.64A 1vm1A-1qoxA:
undetectable		 1vm1A-1qoxA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 5 ALA A 358
ASP A 406
ASP A 424
ASP A 372
 None
 1.18A 2nyuB-1qoxA:
undetectable		 2nyuB-1qoxA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 8 SER A 365
ILE A 370
ASP A 362
ARG A 374
 None
 1.00A 2v57A-1qoxA:
0.0		 2v57A-1qoxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 8 SER A 365
ILE A 370
ASP A 362
ARG A 374
 None
 1.01A 2v57C-1qoxA:
0.0		 2v57C-1qoxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2001_1
(SERUM ALBUMIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 12 TYR A 255
ILE A 254
HIS A 201
TYR A 346
GLY A 218
 None
 1.36A 2vufA-1qoxA:
0.0		 2vufA-1qoxA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2001_1
(SERUM ALBUMIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 12 TYR A 255
ILE A 254
HIS A 201
TYR A 346
GLY A 218
 None
 1.34A 2vufB-1qoxA:
0.0		 2vufB-1qoxA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 12 ILE A 291
GLY A 292
TYR A 352
GLY A 218
PRO A 349
 None
 1.13A 2y7kC-1qoxA:
undetectable		 2y7kC-1qoxA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 10 ILE A 291
GLY A 292
TYR A 352
GLY A 218
PRO A 349
 None
 1.39A 2y7pA-1qoxA:
0.0		 2y7pA-1qoxA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 5 ILE A 219
THR A 342
PHE A 256
TYR A 255
 None
 1.18A 3em0A-1qoxA:
undetectable		 3em0A-1qoxA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 GLU A 412
GLU A 409
TRP A 328
 None
 1.05A 3hrdA-1qoxA:
undetectable
3hrdE-1qoxA:
undetectable
3hrdF-1qoxA:
undetectable		 3hrdA-1qoxA:
20.65
3hrdE-1qoxA:
20.65
3hrdF-1qoxA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 11 GLN A  20
ASN A 165
THR A 354
ILE A 293
ARG A 375
 None
 1.37A 3n23A-1qoxA:
undetectable		 3n23A-1qoxA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_2
(ALPHA-GLUCOSIDASE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 5 PRO A 221
ILE A 219
TYR A 295
TRP A 328
 None
 1.45A 3phaA-1qoxA:
3.7		 3phaA-1qoxA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 7 PRO A 182
ILE A  34
GLN A 129
GLY A 133
 None
 0.97A 4a3uB-1qoxA:
14.5		 4a3uB-1qoxA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 6 LEU A 124
ILE A  34
ASN A 175
VAL A 193
 None
 0.93A 4a9kA-1qoxA:
undetectable		 4a9kA-1qoxA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 PHE A 143
ASP A 141
ARG A 203
 None
 0.90A 4eahF-1qoxA:
undetectable		 4eahF-1qoxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 PHE A 143
ASP A 141
ARG A 203
 None
 0.89A 4eahG-1qoxA:
0.7		 4eahG-1qoxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 9 GLN A  66
LEU A  68
VAL A  73
VAL A 421
LEU A 404
 None
 1.19A 4g1bC-1qoxA:
undetectable		 4g1bC-1qoxA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 7 TYR A 146
ILE A  80
ASP A  99
LEU A  98
GLY A  97
 None
 1.25A 4iqqA-1qoxA:
undetectable		 4iqqA-1qoxA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 8 TYR A 146
ILE A  80
ASP A  99
LEU A  98
GLY A  97
 None
 1.20A 4iqqD-1qoxA:
undetectable		 4iqqD-1qoxA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 5 TYR A 352
ILE A 293
ASN A 395
ILE A 291
 None
 1.07A 4jtpA-1qoxA:
undetectable		 4jtpA-1qoxA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 ASP A 123
TRP A 402
SER A  79
 None
 1.02A 4lrhB-1qoxA:
undetectable		 4lrhB-1qoxA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 SER A 224
ALA A 226
VAL A 227
 None
 0.57A 4x1iA-1qoxA:
2.9		 4x1iA-1qoxA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 SER A 224
ALA A 226
VAL A 227
 None
 0.64A 4x20C-1qoxA:
1.2		 4x20C-1qoxA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 8 ASP A 252
TYR A 341
ASP A 248
ILE A 291
 None
 1.03A 4xjeA-1qoxA:
0.0		 4xjeA-1qoxA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ARF_A_SAMA1002_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 12 GLY A 446
ARG A 445
ALA A 380
TYR A 399
PHE A  10
 None
 1.25A 5arfA-1qoxA:
0.0		 5arfA-1qoxA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 LYS A 440
LEU A 448
ILE A 376
 None
 0.62A 5kc0A-1qoxA:
undetectable		 5kc0A-1qoxA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		3 / 3 LYS A 440
LEU A 448
ILE A 376
 None
 0.83A 5kc4A-1qoxA:
undetectable		 5kc4A-1qoxA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 4 ASN A 301
SER A 224
ALA A 226
VAL A 227
 None
 0.79A 5nm5A-1qoxA:
2.9		 5nm5A-1qoxA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		5 / 8 TYR A 146
ILE A  80
ASP A  99
LEU A  98
GLY A  97
 None
 1.26A 5nooD-1qoxA:
undetectable		 5nooD-1qoxA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 1qox BETA-GLUCOSIDASE
(Bacillus
circulans) 		4 / 6 ILE A  80
ASP A  99
LEU A  98
GLY A  97
 None
 0.98A 5x5qE-1qoxA:
undetectable		 5x5qE-1qoxA:
21.73