SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qoz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 6 GLY A  88
GLY A  20
TYR A  19
SER A  90
 None
 0.97A 1eswA-1qozA:
undetectable		 1eswA-1qozA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG0_A_VIBA702_1
(THIAMIN
PYROPHOSPHOKINASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		5 / 10 GLN A  94
THR A  13
SER A  56
SER A  60
ASN A  59
 None
 1.50A 1ig0A-1qozA:
0.4
1ig0B-1qozA:
0.0		 1ig0A-1qozA:
21.21
1ig0B-1qozA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG0_B_VIBB701_1
(THIAMIN
PYROPHOSPHOKINASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		5 / 9 SER A  56
SER A  60
ASN A  59
GLN A  94
THR A  13
 None
 1.48A 1ig0A-1qozA:
0.4
1ig0B-1qozA:
0.0		 1ig0A-1qozA:
21.21
1ig0B-1qozA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		5 / 11 GLY A  92
GLY A  88
TYR A  89
TYR A 177
PRO A 184
 None
 1.17A 1p91A-1qozA:
undetectable		 1p91A-1qozA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 5 LEU A 140
GLY A 139
HIS A 138
ILE A 137
 None
 0.80A 1xf1A-1qozA:
3.3		 1xf1A-1qozA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 6 LEU A 140
GLY A 139
HIS A 138
ILE A 137
 None
 0.79A 1xf1B-1qozA:
1.9		 1xf1B-1qozA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 8 GLY A  53
THR A  13
ILE A  55
GLN A  49
 None
 1.03A 2a8tB-1qozA:
0.0		 2a8tB-1qozA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		5 / 11 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
 None
 1.20A 2q6hA-1qozA:
undetectable		 2q6hA-1qozA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		5 / 11 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
 None
 1.21A 2qeiA-1qozA:
undetectable		 2qeiA-1qozA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 7 VAL A  26
GLY A   9
ALA A  40
SER A  22
 None
 0.89A 2wekB-1qozA:
3.1		 2wekB-1qozA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 8 GLY A 139
ASN A 143
PHE A 159
TYR A 142
 None
 1.37A 3ccfA-1qozA:
2.1		 3ccfA-1qozA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 7 GLU A 108
ASP A 105
SER A  60
THR A  13
 None
 1.38A 3dzgB-1qozA:
2.1		 3dzgB-1qozA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		3 / 3 TYR A  43
TYR A  57
GLY A  92
 None
 0.66A 3eteB-1qozA:
2.5
3eteD-1qozA:
2.3
3eteF-1qozA:
2.0		 3eteB-1qozA:
18.60
3eteD-1qozA:
18.60
3eteF-1qozA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 6 GLN A  94
TYR A  57
GLN A  49
SER A  90
 None
 1.19A 3peoG-1qozA:
undetectable		 3peoG-1qozA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 7 TYR A  43
ASP A  97
ASP A 133
TYR A  57
 None
 1.05A 3rodD-1qozA:
undetectable		 3rodD-1qozA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		4 / 7 ALA A  93
GLY A   9
ILE A  41
THR A  13
 None
 0.78A 3spkB-1qozA:
undetectable		 3spkB-1qozA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		5 / 12 ALA A 198
ILE A   5
ILE A 129
VAL A  85
VAL A   7
 None
 0.98A 4nkxA-1qozA:
undetectable		 4nkxA-1qozA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		3 / 3 PHE A  96
ILE A  95
ASP A 153
 None
 0.76A 5cswA-1qozA:
undetectable		 5cswA-1qozA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		3 / 3 PHE A  96
ILE A  95
ASP A 153
 None
 0.73A 5cswB-1qozA:
undetectable		 5cswB-1qozA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		3 / 3 ASN A  63
PRO A  44
GLN A  17
 NAG  A 926 (-1.9A)
NAG  A 926 (-3.5A)
None
 0.84A 6jnhA-1qozA:
undetectable		 6jnhA-1qozA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1qoz ACETYL XYLAN
ESTERASE
(Trichoderma
reesei) 		3 / 3 ASN A  63
PRO A  44
GLN A  17
 NAG  A 926 (-1.9A)
NAG  A 926 (-3.5A)
None
 0.84A 6jogA-1qozA:
0.1		 6jogA-1qozA:
20.74