SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qpp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1qpp PAPD CHAPERONE
(Escherichia
coli) 		4 / 8 ASP A 130
THR A 188
PRO A 189
LEU A 156
 None
 0.83A 1z2bB-1qppA:
undetectable		 1z2bB-1qppA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1qpp PAPD CHAPERONE
(Escherichia
coli) 		3 / 3 PRO A  49
THR A  71
PRO A  73
 None
 0.84A 2d55C-1qppA:
undetectable		 2d55C-1qppA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1qpp PAPD CHAPERONE
(Escherichia
coli) 		4 / 7 ARG A 176
GLU A  83
PRO A 117
ALA A 119
 None
 1.43A 2ejgB-1qppA:
undetectable		 2ejgB-1qppA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1qpp PAPD CHAPERONE
(Escherichia
coli) 		4 / 8 SER A  84
GLU A  83
VAL A  50
THR A  71
 None
 1.03A 4lnwA-1qppA:
undetectable		 4lnwA-1qppA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1qpp PAPD CHAPERONE
(Escherichia
coli) 		4 / 6 SER A  84
GLU A  83
VAL A  50
THR A  71
 None
 1.10A 4lnxA-1qppA:
undetectable		 4lnxA-1qppA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1qpp PAPD CHAPERONE
(Escherichia
coli) 		5 / 12 VAL A 202
VAL A 153
GLY A 155
PHE A 205
VAL A 214
 None
 1.20A 6a94B-1qppA:
undetectable		 6a94B-1qppA:
21.93