SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		5 / 11 LEU A 150
LEU A  80
SER A 119
VAL A 144
ILE A 109
 None
 1.33A 1ee2A-1qq0A:
undetectable		 1ee2A-1qq0A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		5 / 11 LEU A 150
LEU A  80
SER A 119
VAL A 144
ILE A 109
 None
 1.38A 1ee2B-1qq0A:
undetectable		 1ee2B-1qq0A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		4 / 6 TYR A 105
GLY A  69
ASP A  70
ASN A 111
 None
 1.20A 2g72A-1qq0A:
undetectable		 2g72A-1qq0A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		6 / 12 SER A  72
ILE A 133
LEU A  80
ASN A  73
THR A 194
VAL A  74
 None
 1.47A 3dcjA-1qq0A:
undetectable
3dcjB-1qq0A:
undetectable		 3dcjA-1qq0A:
21.12
3dcjB-1qq0A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		3 / 3 TYR A 108
ASP A 129
ASP A 163
 None
 0.79A 4a6eA-1qq0A:
undetectable		 4a6eA-1qq0A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		4 / 6 HIS A 193
SER A 192
GLU A 184
ASP A 187
 None
 1.13A 4blvA-1qq0A:
undetectable		 4blvA-1qq0A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		6 / 11 ILE A 161
ILE A 167
VAL A 144
THR A 131
ILE A 133
ALA A 137
 None
 0.97A 5lg3A-1qq0A:
undetectable		 5lg3A-1qq0A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		5 / 12 ILE A 161
ILE A 167
THR A 131
ILE A 133
ALA A 137
 None
 0.85A 5lg3E-1qq0A:
undetectable		 5lg3E-1qq0A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		5 / 12 ILE A 161
ILE A 167
VAL A 144
ILE A 133
ALA A 137
 None
 0.87A 5lg3E-1qq0A:
undetectable		 5lg3E-1qq0A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		5 / 10 ILE A 161
ILE A 167
VAL A 144
THR A 131
ILE A 133
 None
 1.01A 5lg3H-1qq0A:
undetectable		 5lg3H-1qq0A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 1qq0 CARBONIC ANHYDRASE
(Methanosarcina
thermophila) 		5 / 12 GLN A  75
ALA A 116
SER A 114
VAL A 121
TYR A 108
 None
 1.37A 5vlmB-1qq0A:
undetectable		 5vlmB-1qq0A:
22.56