SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qqe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1qqe VESICULAR TRANSPORT
PROTEIN SEC17
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  61
ASP A  58
GLY A  90
ALA A  83
 None
 0.86A 2aohA-1qqeA:
undetectable		 2aohA-1qqeA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1qqe VESICULAR TRANSPORT
PROTEIN SEC17
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 240
ILE A 280
ILE A 276
LEU A 277
GLY A 206
 None
 1.00A 3rukB-1qqeA:
undetectable		 3rukB-1qqeA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 1qqe VESICULAR TRANSPORT
PROTEIN SEC17
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 206
ALA A 247
ILE A 280
LEU A 210
LEU A 207
 None
 1.13A 4xj7A-1qqeA:
undetectable
4xj7B-1qqeA:
undetectable		 4xj7A-1qqeA:
21.57
4xj7B-1qqeA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1qqe VESICULAR TRANSPORT
PROTEIN SEC17
(Saccharomyces
cerevisiae) 		4 / 6 ALA A  63
GLY A  71
ILE A 106
PHE A 107
 None
 0.89A 6f8cA-1qqeA:
undetectable		 6f8cA-1qqeA:
12.80