SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		3 / 3 GLU A1221
ASN A1229
TRP A1255
 None
 1.24A 1r15C-1qqfA:
undetectable		 1r15C-1qqfA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		3 / 3 GLU A1221
ASN A1229
TRP A1255
 None
 1.23A 1r15D-1qqfA:
undetectable		 1r15D-1qqfA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		3 / 3 GLU A1221
ASN A1229
TRP A1255
 None
 1.24A 1r15E-1qqfA:
0.0		 1r15E-1qqfA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		3 / 3 GLU A1221
ASN A1229
TRP A1255
 None
 1.22A 1r15F-1qqfA:
undetectable		 1r15F-1qqfA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 6 LEU A1078
GLY A1011
ILE A1125
HIS A1126
 None
CSO  A1010 ( 2.5A)
None
CSO  A1010 ( 4.8A)
 0.76A 1yajF-1qqfA:
undetectable		 1yajF-1qqfA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		5 / 12 THR A1269
ILE A1130
VAL A1124
ILE A1016
LEU A1078
 None
 1.22A 1z9hD-1qqfA:
undetectable		 1z9hD-1qqfA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 7 ALA A1024
ASP A1029
LEU A1028
ARG A1042
 None
 0.80A 2uyqA-1qqfA:
undetectable		 2uyqA-1qqfA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		3 / 3 ASP A1140
LEU A1143
GLN A1127
 None
 0.77A 3g4lA-1qqfA:
undetectable		 3g4lA-1qqfA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IEO_A_AMJA300_0
(CARBONIC ANHYDRASE 2)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 4 ILE A1130
GLN A1127
VAL A1124
PHE A1133
 None
 1.45A 3ieoA-1qqfA:
undetectable		 3ieoA-1qqfA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 6 PHE A1273
TYR A1081
THR A1019
VAL A1022
 None
 1.26A 3lb3A-1qqfA:
0.0		 3lb3A-1qqfA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		3 / 3 TYR A1081
THR A1019
GLU A1153
 None
 0.73A 4df3A-1qqfA:
undetectable		 4df3A-1qqfA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		3 / 3 TYR A1081
THR A1019
GLU A1153
 None
 0.76A 4df3B-1qqfA:
undetectable		 4df3B-1qqfA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 7 VAL A1141
SER A1142
ALA A1145
GLY A1193
 None
 0.71A 5fpdB-1qqfA:
undetectable		 5fpdB-1qqfA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		5 / 12 ALA A1195
ALA A1192
VAL A1189
LEU A1196
GLY A1173
 None
 1.30A 5igpA-1qqfA:
undetectable		 5igpA-1qqfA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 6 LEU A1088
ILE A1016
THR A1019
MET A1129
 None
 1.44A 5ljeA-1qqfA:
undetectable		 5ljeA-1qqfA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 7 LEU A1107
ALA A1150
ILE A1169
LEU A1165
 None
 0.83A 5te8C-1qqfA:
undetectable		 5te8C-1qqfA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1qqf PROTEIN (COMPLEMENT
C3DG)
(Rattus
norvegicus) 		4 / 7 VAL A1082
VAL A1022
GLY A1052
TYR A1053
 None
 1.02A 5x80C-1qqfA:
undetectable
5x80D-1qqfA:
undetectable		 5x80C-1qqfA:
20.21
5x80D-1qqfA:
20.21