SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qqh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.84A 1a7yB-1qqhA:
undetectable		 1a7yB-1qqhA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.85A 1i3wE-1qqhA:
undetectable		 1i3wE-1qqhA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.87A 1ovfB-1qqhA:
undetectable		 1ovfB-1qqhA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.86A 1qfiB-1qqhA:
undetectable		 1qfiB-1qqhA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.81A 1unjF-1qqhA:
undetectable		 1unjF-1qqhA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.86A 1unjX-1qqhA:
undetectable		 1unjX-1qqhA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY A 157
TRP A 185
VAL A 119
 None
 0.60A 3n62B-1qqhA:
undetectable		 3n62B-1qqhA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY A 157
TRP A 185
VAL A 119
 None
 0.60A 3n65B-1qqhA:
undetectable		 3n65B-1qqhA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY A 157
TRP A 185
VAL A 119
 None
 0.61A 3n66B-1qqhA:
undetectable		 3n66B-1qqhA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		4 / 5 GLY A 157
ILE A 170
TRP A 185
VAL A 187
 None
 1.15A 4d33A-1qqhA:
undetectable		 4d33A-1qqhA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		4 / 6 VAL A 187
GLN A 118
VAL A 117
TYR A 131
 None
 1.04A 5i8fA-1qqhA:
undetectable		 5i8fA-1qqhA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 VAL A 137
SER A 136
TRP A 134
 None
 1.08A 5jwaA-1qqhA:
undetectable		 5jwaA-1qqhA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		5 / 9 ASP A  96
GLY A 113
GLY A 114
ALA A 133
VAL A 132
 None
 1.16A 5v3cA-1qqhA:
undetectable		 5v3cA-1qqhA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY A 157
TRP A 185
VAL A 119
 None
 0.61A 5vuoB-1qqhA:
undetectable		 5vuoB-1qqhA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 1qqh PAPILLOMAVIRUS
TRANSCRIPTION FACTOR
E2
(Alphapapillomavi
rus
7) 		4 / 5 GLN A 115
THR A 116
THR A 104
GLY A 113
 None
 1.21A 6gbnC-1qqhA:
undetectable		 6gbnC-1qqhA:
16.78