SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FDS_A_ESTA350_1 (17-BETA-HYDROXYSTERO ID-DEHYDROGENASE)	1qql	FIBROBLAST GROWTH FACTOR 7/1 CHIMERA (Homo sapiens; Rattus norvegicus)	5 / 12	VAL A 109 LEU A 65 GLY A 110 PHE A 132 MET A 44	None	1.41A	1fdsA-1qqlA: undetectable	1fdsA-1qqlA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TMZ_A_06XA504_1 (CYTOCHROME P450 2B4)	1qql	FIBROBLAST GROWTH FACTOR 7/1 CHIMERA (Homo sapiens; Rattus norvegicus)	5 / 9	LEU A 65 LEU A 23 ILE A 10 PHE A 85 VAL A 54	None	1.47A	3tmzA-1qqlA: 0.0	3tmzA-1qqlA: 15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7U_D_YTZD802_1 (SEPIAPTERIN REDUCTASE)	1qql	FIBROBLAST GROWTH FACTOR 7/1 CHIMERA (Homo sapiens; Rattus norvegicus)	4 / 8	LEU A 111 CYH A 17 PHE A 132 GLN A 127	None	1.14A	4j7uD-1qqlA: undetectable	4j7uD-1qqlA: 19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	1qql	FIBROBLAST GROWTH FACTOR 7/1 CHIMERA (Homo sapiens; Rattus norvegicus)	4 / 6	LYS A 112 LEU A 111 PHE A 132 LEU A 23	None	1.12A	5x19P-1qqlA: undetectable	5x19P-1qqlA: 20.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FDS_A_ESTA350_1","17-BETA-HYDROXYSTEROID-DEHYDROGENASE","1qql","FIBROBLAST GROWTH FACTOR 7\/1 CHIMERA","Homo sapiens;Rattus norvegicus",5,"VAL A 109;LEU A  65;GLY A 110;PHE A 132;MET A  44","None","1.41A","1fdsA-1qqlA:undetectable","1fdsA-1qqlA:18.61"],["3TMZ_A_06XA504_1","CYTOCHROME P450 2B4","1qql","FIBROBLAST GROWTH FACTOR 7\/1 CHIMERA","Homo sapiens;Rattus norvegicus",5,"LEU A  65;LEU A  23;ILE A  10;PHE A  85;VAL A  54","None","1.47A","3tmzA-1qqlA:0.0","3tmzA-1qqlA:15.65"],["4J7U_D_YTZD802_1","SEPIAPTERIN REDUCTASE","1qql","FIBROBLAST GROWTH FACTOR 7\/1 CHIMERA","Homo sapiens;Rattus norvegicus",4,"LEU A 111;CYH A  17;PHE A 132;GLN A 127","None","1.14A","4j7uD-1qqlA:undetectable","4j7uD-1qqlA:19.43"],["5X19_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3","1qql","FIBROBLAST GROWTH FACTOR 7\/1 CHIMERA","Homo sapiens;Rattus norvegicus",4,"LYS A 112;LEU A 111;PHE A 132;LEU A  23","None","1.12A","5x19P-1qqlA:undetectable","5x19P-1qqlA:20.90"]]