SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		4 / 7 ASP A 107
GLU A 109
TRP A 147
PHE A 122
 MG  A 400 ( 2.8A)
MG  A 400 (-3.3A)
None
None
 1.18A 1b2iA-1qr0A:
0.0		 1b2iA-1qr0A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		4 / 7 VAL A  95
ASN A  87
ASP A 107
LYS A 155
 None
COA  A 300 (-3.4A)
MG  A 400 ( 2.8A)
COA  A 300 (-2.8A)
 1.32A 1hwiC-1qr0A:
undetectable		 1hwiC-1qr0A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		4 / 7 VAL A  95
ASN A  87
ASP A 107
LYS A 155
 None
COA  A 300 (-3.4A)
MG  A 400 ( 2.8A)
COA  A 300 (-2.8A)
 1.33A 1hwiD-1qr0A:
undetectable		 1hwiD-1qr0A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		3 / 3 PHE A 122
TRP A 147
GLU A 109
 None
None
MG  A 400 (-3.3A)
 1.14A 1mogA-1qr0A:
1.0		 1mogA-1qr0A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		5 / 9 ALA A 203
ALA A  98
GLY A  97
GLY A 105
ILE A 104
 None
 1.23A 2v7bA-1qr0A:
undetectable		 2v7bA-1qr0A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		5 / 9 ALA A 203
ALA A  98
GLY A  97
GLY A 105
ILE A 104
 None
 1.23A 2v7bB-1qr0A:
undetectable		 2v7bB-1qr0A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		5 / 10 ILE A   3
GLY A  97
GLY A 105
PRO A 212
ILE A 104
 None
 0.98A 2y7wB-1qr0A:
undetectable		 2y7wB-1qr0A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		5 / 10 ILE A 191
ALA A 203
GLU A 151
GLY A  97
LYS A 155
 None
None
COA  A 300 ( 2.7A)
None
COA  A 300 (-2.8A)
 1.38A 4e47D-1qr0A:
undetectable		 4e47D-1qr0A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		5 / 11 ILE A 191
ALA A 203
GLU A 151
GLY A  97
LYS A 155
 None
None
COA  A 300 ( 2.7A)
None
COA  A 300 (-2.8A)
 1.34A 4jdsD-1qr0A:
undetectable		 4jdsD-1qr0A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		5 / 11 ILE A 191
ALA A 203
GLU A 151
GLY A  97
LYS A 155
 None
None
COA  A 300 ( 2.7A)
None
COA  A 300 (-2.8A)
 1.32A 4jlgB-1qr0A:
0.0		 4jlgB-1qr0A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		3 / 3 CYH A  32
PRO A  26
ASP A  48
 None
 0.95A 4pm5A-1qr0A:
undetectable		 4pm5A-1qr0A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		4 / 4 TYR A   4
THR A 216
GLY A   5
LEU A 223
 None
 1.31A 4w5nA-1qr0A:
0.3		 4w5nA-1qr0A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		4 / 7 VAL A 204
LEU A  45
PHE A  99
LEU A  50
 None
 1.06A 6aycA-1qr0A:
undetectable		 6aycA-1qr0A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 1qr0 4'-PHOSPHOPANTETHEIN
YL TRANSFERASE SFP
(Bacillus
subtilis) 		4 / 8 GLY A  97
LEU A  46
GLY A  47
LEU A  50
 None
 0.86A 6mdqA-1qr0A:
undetectable		 6mdqA-1qr0A:
16.82