SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qr4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qr4 PROTEIN (TENASCIN)
(Gallus
gallus) 		4 / 5 PRO A 110
THR A  86
VAL A  87
GLY A  61
 None
 0.98A 3elzA-1qr4A:
1.2		 3elzA-1qr4A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 1qr4 PROTEIN (TENASCIN)
(Gallus
gallus) 		5 / 10 ILE A  66
SER A  85
LYS A  83
GLY A  84
LEU A   6
 None
 1.24A 3ik6B-1qr4A:
0.0
3ik6E-1qr4A:
0.0		 3ik6B-1qr4A:
22.69
3ik6E-1qr4A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1qr4 PROTEIN (TENASCIN)
(Gallus
gallus) 		5 / 10 LEU A   6
ILE A  66
SER A  85
LYS A  83
GLY A  84
 None
 1.14A 3ik6B-1qr4A:
undetectable
3ik6E-1qr4A:
undetectable		 3ik6B-1qr4A:
22.69
3ik6E-1qr4A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 1qr4 PROTEIN (TENASCIN)
(Gallus
gallus) 		5 / 11 ILE A  66
SER A  85
LYS A  83
GLY A  84
LEU A   6
 None
 1.16A 3iluB-1qr4A:
0.0
3iluE-1qr4A:
0.0		 3iluB-1qr4A:
22.69
3iluE-1qr4A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 1qr4 PROTEIN (TENASCIN)
(Gallus
gallus) 		4 / 4 LEU A  68
MET A  44
ILE A  82
LEU A  55
 None
 1.41A 5nfpA-1qr4A:
undetectable		 5nfpA-1qr4A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1qr4 PROTEIN (TENASCIN)
(Gallus
gallus) 		3 / 3 GLU A   7
ASP A  10
PRO A  11
 None
 0.65A 6berA-1qr4A:
undetectable		 6berA-1qr4A:
5.56