SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 7 GLU A  86
LEU A  54
VAL A 299
LEU A 337
 None
 1.00A 1hk3A-1qr7A:
0.3		 1hk3A-1qr7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 160
GLY A 184
ILE A  43
GLU A  96
ALA A 176
 None
 0.85A 1nv8B-1qr7A:
undetectable		 1nv8B-1qr7A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 6 VAL A 262
ILE A 297
TRP A 159
TYR A  94
 None
None
None
PEP  A1352 (-4.3A)
 0.96A 1s9qA-1qr7A:
undetectable		 1s9qA-1qr7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 160
GLY A 184
ILE A  43
GLU A  96
ALA A 176
 None
 0.85A 1sg9B-1qr7A:
undetectable		 1sg9B-1qr7A:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 160
GLY A 184
ILE A  43
GLU A  96
ALA A 176
 None
 0.96A 1vq1B-1qr7A:
undetectable		 1vq1B-1qr7A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 153
PHE A  95
VAL A  93
MET A  91
ALA A  69
 None
 1.47A 2jj8B-1qr7A:
undetectable		 2jj8B-1qr7A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 6 PRO A 182
GLY A 160
ILE A 232
GLY A 184
 None
 0.87A 2jkjA-1qr7A:
undetectable		 2jkjA-1qr7A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 6 PRO A 182
GLY A 160
ILE A 232
GLY A 184
 None
 0.87A 2jkjB-1qr7A:
undetectable		 2jkjB-1qr7A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 6 PRO A 182
GLY A 160
ILE A 232
GLY A 184
 None
 0.87A 2jkjC-1qr7A:
undetectable		 2jkjC-1qr7A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 6 PRO A 182
GLY A 160
ILE A 232
GLY A 184
 None
 0.86A 2jklB-1qr7A:
undetectable		 2jklB-1qr7A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 7 PRO A 182
GLY A 160
ILE A 232
GLY A 184
 None
 0.85A 2jklE-1qr7A:
undetectable		 2jklE-1qr7A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 8 LEU A  54
ILE A  43
GLY A 184
ILE A 232
 None
 0.75A 2o4nB-1qr7A:
undetectable		 2o4nB-1qr7A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 8 SER A 271
GLN A 278
VAL A  57
ARG A  92
 None
None
None
PEP  A1352 (-3.2A)
 1.10A 3b9lA-1qr7A:
undetectable		 3b9lA-1qr7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		5 / 9 ALA A 140
ILE A  63
GLY A  59
ILE A  58
ILE A 133
 None
 1.01A 3ndwB-1qr7A:
undetectable		 3ndwB-1qr7A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 8 LEU A 107
ASP A 110
ASP A 114
SER A 116
 None
 1.00A 3qj7A-1qr7A:
undetectable
3qj7D-1qr7A:
undetectable		 3qj7A-1qr7A:
22.59
3qj7D-1qr7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		5 / 12 ALA A  39
LEU A 138
ILE A  58
LEU A  76
LEU A  55
 None
 1.15A 4j24D-1qr7A:
undetectable		 4j24D-1qr7A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 5 LEU A 258
PRO A 259
LEU A 253
ILE A 197
 None
 1.02A 4klrA-1qr7A:
undetectable		 4klrA-1qr7A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 142
LEU A 130
MET A 157
THR A 149
ILE A 108
 None
 1.13A 4okbA-1qr7A:
0.0		 4okbA-1qr7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 7 LEU A 107
PHE A  95
ILE A 148
ASN A 120
 None
 1.01A 5n5dA-1qr7A:
undetectable		 5n5dA-1qr7A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 7 ILE A  58
ARG A  75
THR A  74
LEU A 138
 None
 0.97A 5zcpA-1qr7A:
0.4
5zcpJ-1qr7A:
undetectable		 5zcpA-1qr7A:
21.06
5zcpJ-1qr7A:
10.46