SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qrd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		3 / 3 TYR A 132
GLY A 180
PHE A 178
 None
 0.69A 2m2pB-1qrdA:
undetectable		 2m2pB-1qrdA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		3 / 3 LEU A 112
LEU A   6
PHE A 116
 None
 0.68A 2pgrA-1qrdA:
undetectable		 2pgrA-1qrdA:
23.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		4 / 8 TRP A 105
PHE A 106
GLY A 149
MET A 154
 DQN  A 276 ( 3.6A)
DQN  A 276 ( 4.2A)
CBD  A 275 ( 3.7A)
CBD  A 275 ( 4.4A)
 0.45A 2qwxA-1qrdA:
29.6
2qwxB-1qrdA:
29.7		 2qwxA-1qrdA:
41.88
2qwxB-1qrdA:
41.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		5 / 8 TRP A 105
PHE A 106
GLY A 149
GLY A 150
MET A 154
 DQN  A 276 ( 3.6A)
DQN  A 276 ( 4.2A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
 0.46A 2qx4A-1qrdA:
29.7
2qx4B-1qrdA:
29.7		 2qx4A-1qrdA:
41.88
2qx4B-1qrdA:
41.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		6 / 10 TRP A 105
PHE A 106
GLY A 149
GLY A 150
MET A 154
TYR A 155
 DQN  A 276 ( 3.6A)
DQN  A 276 ( 4.2A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
None
 0.48A 3fw1A-1qrdA:
29.6		 3fw1A-1qrdA:
41.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		6 / 9 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
VAL A 160
 DQN  A 276 ( 3.6A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
None
None
 0.55A 3owxA-1qrdA:
29.6		 3owxA-1qrdA:
41.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		5 / 11 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
 DQN  A 276 ( 3.6A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
None
 0.41A 3owxA-1qrdA:
29.6
3owxB-1qrdA:
29.6		 3owxA-1qrdA:
41.88
3owxB-1qrdA:
41.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		5 / 7 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
 DQN  A 276 ( 3.6A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
None
 0.44A 4fgkB-1qrdA:
29.6		 4fgkB-1qrdA:
41.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		4 / 6 ASN A  18
MET A 164
LEU A 188
VAL A 203
 FAD  A 274 (-3.8A)
None
None
None
 1.13A 4okbA-1qrdA:
undetectable		 4okbA-1qrdA:
21.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		4 / 8 TRP A 105
PHE A 106
GLY A 149
MET A 154
 DQN  A 276 ( 3.6A)
DQN  A 276 ( 4.2A)
CBD  A 275 ( 3.7A)
CBD  A 275 ( 4.4A)
 0.45A 4qogA-1qrdA:
29.6
4qogB-1qrdA:
29.2		 4qogA-1qrdA:
41.88
4qogB-1qrdA:
41.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		5 / 12 GLU A  23
ILE A   7
ALA A   5
ILE A  98
SER A 145
 None
 1.28A 4uroC-1qrdA:
undetectable		 4uroC-1qrdA:
21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LBT_A_6T0A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		5 / 10 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
 DQN  A 276 ( 3.6A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
None
 0.47A 5lbtA-1qrdA:
29.5
5lbtB-1qrdA:
29.1		 5lbtA-1qrdA:
45.25
5lbtB-1qrdA:
45.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		5 / 10 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
 DQN  A 276 ( 3.6A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
None
 0.46A 5lbtA-1qrdA:
29.5
5lbtB-1qrdA:
29.1		 5lbtA-1qrdA:
45.25
5lbtB-1qrdA:
45.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		3 / 3 ARG A  14
PHE A  17
LEU A   9
 None
FAD  A 274 (-4.9A)
None
 0.95A 5x1bC-1qrdA:
undetectable		 5x1bC-1qrdA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		4 / 8 ILE A 171
ASN A  18
LEU A  41
ALA A  10
 None
FAD  A 274 (-3.8A)
None
None
 0.81A 5y7pC-1qrdA:
0.0		 5y7pC-1qrdA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		4 / 8 ILE A 171
ASN A  18
LEU A  41
ALA A  10
 None
FAD  A 274 (-3.8A)
None
None
 0.76A 5y7pE-1qrdA:
undetectable		 5y7pE-1qrdA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1qrd QUINONE-REDUCTASE
(Rattus
rattus) 		4 / 4 ASP A  40
ILE A 111
PRO A  48
LEU A  41
 None
 1.45A 6mkeB-1qrdA:
undetectable		 6mkeB-1qrdA:
14.65