SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qrh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		4 / 8 SER A 195
ASN A 199
LEU A 201
ASP A 202
 None
 0.77A 1mxgA-1qrhA:
undetectable		 1mxgA-1qrhA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 9 GLU A  96
ILE A  94
LYS A  62
GLU A  65
ILE A  61
 None
 1.12A 2j9dA-1qrhA:
0.5
2j9dB-1qrhA:
0.3
2j9dC-1qrhA:
0.0		 2j9dA-1qrhA:
19.84
2j9dB-1qrhA:
19.84
2j9dC-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 9 GLU A  96
ILE A  94
LYS A  62
GLU A  65
ILE A  61
 None
 1.12A 2j9dA-1qrhA:
0.5
2j9dB-1qrhA:
0.3
2j9dC-1qrhA:
0.0		 2j9dA-1qrhA:
19.84
2j9dB-1qrhA:
19.84
2j9dC-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 9 LYS A  62
GLU A  65
ILE A  61
GLU A  96
ILE A  94
 None
 1.10A 2j9dA-1qrhA:
0.5
2j9dB-1qrhA:
0.3
2j9dC-1qrhA:
0.0		 2j9dA-1qrhA:
19.84
2j9dB-1qrhA:
19.84
2j9dC-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 10 GLU A  96
ILE A  94
LYS A  62
GLU A  65
ILE A  61
 None
 1.11A 2j9dD-1qrhA:
0.2
2j9dE-1qrhA:
0.2
2j9dF-1qrhA:
0.4		 2j9dD-1qrhA:
19.84
2j9dE-1qrhA:
19.84
2j9dF-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 10 GLU A  96
ILE A  94
LYS A  62
GLU A  65
ILE A  61
 None
 1.13A 2j9dD-1qrhA:
0.2
2j9dE-1qrhA:
0.2
2j9dF-1qrhA:
0.4		 2j9dD-1qrhA:
19.84
2j9dE-1qrhA:
19.84
2j9dF-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 10 LYS A  62
GLU A  65
ILE A  61
GLU A  96
ILE A  94
 None
 1.13A 2j9dD-1qrhA:
0.2
2j9dE-1qrhA:
0.2
2j9dF-1qrhA:
0.4		 2j9dD-1qrhA:
19.84
2j9dE-1qrhA:
19.84
2j9dF-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 9 GLU A  96
ILE A  94
LYS A  62
GLU A  65
ILE A  61
 None
 1.08A 2j9dG-1qrhA:
0.5
2j9dH-1qrhA:
0.4
2j9dI-1qrhA:
0.0		 2j9dG-1qrhA:
19.84
2j9dH-1qrhA:
19.84
2j9dI-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 9 GLU A  96
ILE A  94
LYS A  62
GLU A  65
ILE A  61
 None
 1.10A 2j9dG-1qrhA:
0.5
2j9dH-1qrhA:
0.4
2j9dI-1qrhA:
0.0		 2j9dG-1qrhA:
19.84
2j9dH-1qrhA:
19.84
2j9dI-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 9 LYS A  62
GLU A  65
ILE A  61
GLU A  96
ILE A  94
 None
 1.09A 2j9dG-1qrhA:
0.5
2j9dH-1qrhA:
0.4
2j9dI-1qrhA:
0.0		 2j9dG-1qrhA:
19.84
2j9dH-1qrhA:
19.84
2j9dI-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 8 GLU A  96
ILE A  94
LYS A  62
GLU A  65
ILE A  61
 None
 1.05A 2j9dJ-1qrhA:
0.0
2j9dK-1qrhA:
0.0
2j9dL-1qrhA:
0.0		 2j9dJ-1qrhA:
19.84
2j9dK-1qrhA:
19.84
2j9dL-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		4 / 8 LYS A  62
GLU A  65
ILE A  61
GLU A  96
 None
 0.98A 2j9dJ-1qrhA:
0.0
2j9dK-1qrhA:
0.0
2j9dL-1qrhA:
0.0		 2j9dJ-1qrhA:
19.84
2j9dK-1qrhA:
19.84
2j9dL-1qrhA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		4 / 6 LEU A 204
LEU A 201
ILE A 143
ARG A 200
 None
 0.94A 2rlfC-1qrhA:
undetectable
2rlfD-1qrhA:
undetectable		 2rlfC-1qrhA:
11.88
2rlfD-1qrhA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 7 ILE A 153
PHE A 156
VAL A 109
ILE A  94
GLU A  96
 None
 1.44A 4zzbC-1qrhA:
undetectable
4zzbD-1qrhA:
undetectable		 4zzbC-1qrhA:
24.48
4zzbD-1qrhA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		4 / 6 ILE A 153
PHE A 156
ILE A  94
GLU A  96
 None
 1.04A 4zzcA-1qrhA:
undetectable
4zzcB-1qrhA:
undetectable		 4zzcA-1qrhA:
25.37
4zzcB-1qrhA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		4 / 6 ILE A 153
PHE A 156
ILE A  94
GLU A  96
 None
 1.07A 4zzcB-1qrhA:
undetectable
4zzcC-1qrhA:
undetectable		 4zzcB-1qrhA:
25.37
4zzcC-1qrhA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 1qrh ECO RI ENDONCULEASE
(Escherichia
coli) 		5 / 12 ALA A 139
THR A 239
ILE A 143
PHE A 174
ASN A 199
 None
 1.12A 5hgcA-1qrhA:
undetectable		 5hgcA-1qrhA:
21.68