SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qrr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ASP A 189
THR A 124
ILE A  76
HIS A  96
 None
None
NAD  A 401 (-3.9A)
None
 1.00A 1ei6C-1qrrA:
2.0		 1ei6C-1qrrA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 GLN A 366
ILE A 376
HIS A 251
 None
 0.74A 1fm9A-1qrrA:
undetectable		 1fm9A-1qrrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 GLN A 366
ILE A 376
HIS A 251
 None
 0.70A 1k74A-1qrrA:
0.0		 1k74A-1qrrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ARG A 327
ASP A 231
ASN A 228
 UPG  A 402 (-2.7A)
None
None
 0.76A 1nbhA-1qrrA:
7.3		 1nbhA-1qrrA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ARG A 327
ASP A 231
ASN A 228
 UPG  A 402 (-2.7A)
None
None
 0.76A 1nbhD-1qrrA:
7.0		 1nbhD-1qrrA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 HIS A 251
MET A 321
MET A 377
 None
 1.23A 2vj1A-1qrrA:
0.0		 2vj1A-1qrrA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 THR A  65
LEU A  64
VAL A  28
TYR A  26
VAL A   6
 None
 1.05A 3frqB-1qrrA:
undetectable		 3frqB-1qrrA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLU A 302
ASN A 301
GLY A 260
VAL A 318
ARG A 263
 None
None
None
None
UPG  A 402 (-3.7A)
 1.28A 3k13A-1qrrA:
3.4		 3k13A-1qrrA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ASN A 120
GLY A 123
CYH A 197
PHE A 288
LYS A 142
 None
 1.48A 3r24A-1qrrA:
4.9		 3r24A-1qrrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A  14
GLY A   9
GLY A   8
LEU A 143
VAL A 212
 None
None
NAD  A 401 (-3.3A)
NAD  A 401 (-3.9A)
NAD  A 401 (-3.9A)
 0.97A 4htfA-1qrrA:
6.7		 4htfA-1qrrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A  14
GLY A   9
GLY A   8
LEU A 143
VAL A 212
 None
None
NAD  A 401 (-3.3A)
NAD  A 401 (-3.9A)
NAD  A 401 (-3.9A)
 0.94A 4htfB-1qrrA:
6.8		 4htfB-1qrrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 11 GLY A   8
GLY A   9
THR A  17
ASP A  32
ASP A  75
 NAD  A 401 (-3.3A)
None
None
NAD  A 401 (-2.8A)
NAD  A 401 (-3.5A)
 0.83A 4pghA-1qrrA:
5.5		 4pghA-1qrrA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ASN A 362
VAL A 365
LEU A 240
ALA A 247
ASP A 358
 None
 1.30A 4qckA-1qrrA:
0.0		 4qckA-1qrrA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ILE A 193
SER A 190
ALA A 194
GLU A 148
TYR A 149
 None
 1.32A 4xt8A-1qrrA:
undetectable		 4xt8A-1qrrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 GLN A 366
ILE A 376
HIS A 251
 None
 0.70A 5z12B-1qrrA:
0.0		 5z12B-1qrrA:
12.57