SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1qso HPA2 HISTONE
ACETYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  92
ASN A  74
PHE A  49
ALA A  58
 None
 1.02A 1rqpC-1qsoA:
undetectable		 1rqpC-1qsoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1qso HPA2 HISTONE
ACETYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  92
ASN A  74
PHE A  49
ALA A  58
 None
 1.01A 1rqpA-1qsoA:
undetectable		 1rqpA-1qsoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1qso HPA2 HISTONE
ACETYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ILE A 109
LEU A  93
ILE A  73
 None
 0.88A 2q83A-1qsoA:
undetectable		 2q83A-1qsoA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1qso HPA2 HISTONE
ACETYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  92
ASN A  74
PHE A  49
ALA A  58
 None
 0.97A 2v7uA-1qsoA:
undetectable		 2v7uA-1qsoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1qso HPA2 HISTONE
ACETYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 9 PHE A  46
ASN A  74
LEU A 108
VAL A  11
ILE A  73
 None
 1.41A 3claA-1qsoA:
0.0		 3claA-1qsoA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 1qso HPA2 HISTONE
ACETYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  18
ILE A  73
ARG A  12
VAL A 112
ILE A  90
 None
 1.01A 4q5mA-1qsoA:
undetectable		 4q5mA-1qsoA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1qso HPA2 HISTONE
ACETYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY A  71
ALA A  58
VAL A  60
ASP A  96
ILE A  69
 None
 1.18A 5i3cB-1qsoA:
undetectable		 5i3cB-1qsoA:
20.68