SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qst'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1qst TGCN5 HISTONE ACETYL
TRANSFERASE
(Tetrahymena
thermophila) 		4 / 7 LEU A  49
ILE A 107
GLN A  76
ILE A  85
 None
 0.73A 2xkwA-1qstA:
undetectable		 2xkwA-1qstA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qst TGCN5 HISTONE ACETYL
TRANSFERASE
(Tetrahymena
thermophila) 		4 / 7 ILE A  72
LEU A  69
ARG A 135
LEU A 141
 None
 0.96A 5b1aA-1qstA:
undetectable
5b1aJ-1qstA:
undetectable		 5b1aA-1qstA:
13.35
5b1aJ-1qstA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qst TGCN5 HISTONE ACETYL
TRANSFERASE
(Tetrahymena
thermophila) 		4 / 7 ILE A  72
LEU A  69
ARG A 135
LEU A 141
 None
 0.98A 5b3sA-1qstA:
undetectable
5b3sJ-1qstA:
undetectable		 5b3sA-1qstA:
13.35
5b3sJ-1qstA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qst TGCN5 HISTONE ACETYL
TRANSFERASE
(Tetrahymena
thermophila) 		3 / 3 VAL A 106
SER A  96
MET A 142
 None
 0.80A 5ikqA-1qstA:
0.0		 5ikqA-1qstA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1qst TGCN5 HISTONE ACETYL
TRANSFERASE
(Tetrahymena
thermophila) 		3 / 3 LYS A  64
LEU A  65
ARG A  61
 None
 0.75A 5yw0A-1qstA:
undetectable		 5yw0A-1qstA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qst TGCN5 HISTONE ACETYL
TRANSFERASE
(Tetrahymena
thermophila) 		4 / 7 ILE A  72
LEU A  69
ARG A 135
LEU A 141
 None
 0.92A 5zcqA-1qstA:
undetectable
5zcqJ-1qstA:
undetectable		 5zcqA-1qstA:
13.35
5zcqJ-1qstA:
15.19