SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qu0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		5 / 11 LEU A3105
LEU A3107
ALA A2946
PHE A3061
GLY A3063
 None
 1.33A 1cmaA-1qu0A:
undetectable
1cmaB-1qu0A:
undetectable		 1cmaA-1qu0A:
19.07
1cmaB-1qu0A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		5 / 11 PHE A2940
PHE A3080
LEU A3089
VAL A2960
VAL A3060
 None
 1.14A 1q23J-1qu0A:
undetectable		 1q23J-1qu0A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		4 / 4 LEU A2974
ALA A2948
VAL A2949
PRO A3059
 None
 1.04A 3gv1B-1qu0A:
undetectable		 3gv1B-1qu0A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		3 / 3 GLU A2987
HIS A2996
THR A3075
 None
 0.81A 3hkuA-1qu0A:
undetectable		 3hkuA-1qu0A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		5 / 12 GLY A3002
ALA A3001
PHE A3072
SER A2978
ASN A2999
 None
 1.40A 3s8pA-1qu0A:
undetectable		 3s8pA-1qu0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		5 / 12 VAL A3110
PHE A3080
LEU A3087
PHE A2962
GLY A3063
 None
 1.44A 4pevC-1qu0A:
undetectable		 4pevC-1qu0A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		5 / 12 ALA A2946
THR A3056
VAL A2954
LEU A2974
LEU A3074
 None
 1.32A 4qzuA-1qu0A:
undetectable		 4qzuA-1qu0A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 1qu0 LAMININ ALPHA2 CHAIN
(Mus
musculus) 		4 / 8 VAL A3060
GLY A3073
GLN A3071
LEU A3074
 None
 0.97A 5syjB-1qu0A:
undetectable		 5syjB-1qu0A:
14.37