SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qu5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 1qu5 PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 649
ILE A 625
LEU A 578
LEU A 580
 None
 1.09A 2zb7A-1qu5A:
undetectable		 2zb7A-1qu5A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 1qu5 PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 580
ASP A 615
LEU A 618
HIS A 622
 None
 1.15A 3bj8C-1qu5A:
0.0
3bj8D-1qu5A:
0.0		 3bj8C-1qu5A:
20.74
3bj8D-1qu5A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1qu5 PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		5 / 12 CYH A 623
GLY A 653
LEU A 618
ASN A 655
ILE A 603
 None
 0.81A 4n49A-1qu5A:
undetectable		 4n49A-1qu5A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1qu5 PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		5 / 12 SER A 657
ILE A 696
PHE A 577
LEU A 717
TYR A 649
 None
 1.39A 6a93A-1qu5A:
undetectable		 6a93A-1qu5A:
19.72