SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qu7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 7 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.08A 1rxcD-1qu7A:
undetectable		 1rxcD-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 7 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.07A 1rxcF-1qu7A:
undetectable		 1rxcF-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 7 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.08A 1rxcL-1qu7A:
undetectable		 1rxcL-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 5 SER A 432
VAL A 348
SER A 355
VAL A 428
 None
 1.10A 2j9cA-1qu7A:
undetectable
2j9cB-1qu7A:
undetectable
2j9cC-1qu7A:
undetectable		 2j9cA-1qu7A:
20.27
2j9cB-1qu7A:
20.27
2j9cC-1qu7A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		3 / 3 ASP A 464
THR A 450
GLU A 458
 None
 0.71A 2zifB-1qu7A:
undetectable		 2zifB-1qu7A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 6 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.09A 3kvvA-1qu7A:
undetectable		 3kvvA-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 6 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.06A 3kvvB-1qu7A:
undetectable		 3kvvB-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 6 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.07A 3kvvC-1qu7A:
undetectable		 3kvvC-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 6 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.12A 3kvvD-1qu7A:
undetectable		 3kvvD-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 6 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.09A 3kvvE-1qu7A:
undetectable		 3kvvE-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 6 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.07A 3kvvF-1qu7A:
undetectable		 3kvvF-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		4 / 6 GLY A 370
GLN A 374
ILE A 368
VAL A 367
 None
 1.06A 4e1vF-1qu7A:
undetectable		 4e1vF-1qu7A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		5 / 10 GLY A 426
VAL A 425
VAL A 428
LEU A 420
SER A 358
 None
 1.27A 4yb6A-1qu7A:
undetectable
4yb6E-1qu7A:
undetectable		 4yb6A-1qu7A:
23.30
4yb6E-1qu7A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		5 / 10 GLY A 426
VAL A 425
VAL A 428
LEU A 420
SER A 358
 None
 1.28A 4yb6B-1qu7A:
undetectable
4yb6C-1qu7A:
undetectable		 4yb6B-1qu7A:
23.30
4yb6C-1qu7A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I
(Escherichia
coli) 		5 / 10 LEU A 420
SER A 358
GLY A 426
VAL A 425
VAL A 428
 None
 1.27A 4yb6B-1qu7A:
undetectable
4yb6F-1qu7A:
undetectable		 4yb6B-1qu7A:
23.30
4yb6F-1qu7A:
23.30