SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		4 / 7 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.45A 1oniA-1qu9A:
22.1
1oniB-1qu9A:
21.9		 1oniA-1qu9A:
44.78
1oniB-1qu9A:
44.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		4 / 6 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.42A 1oniB-1qu9A:
21.9
1oniC-1qu9A:
21.8		 1oniB-1qu9A:
44.78
1oniC-1qu9A:
44.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		4 / 6 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.37A 1oniA-1qu9A:
22.1
1oniC-1qu9A:
21.8		 1oniA-1qu9A:
44.78
1oniC-1qu9A:
44.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		4 / 7 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.46A 1oniD-1qu9A:
22.1
1oniE-1qu9A:
22.2		 1oniD-1qu9A:
44.78
1oniE-1qu9A:
44.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		4 / 7 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.44A 1oniG-1qu9A:
21.8
1oniI-1qu9A:
21.9		 1oniG-1qu9A:
44.78
1oniI-1qu9A:
44.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		3 / 3 GLY A  69
ASP A  70
ASN A  99
 None
 0.59A 1vq1A-1qu9A:
undetectable		 1vq1A-1qu9A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		4 / 7 ALA A  89
THR A  90
ALA A  93
ARG A  51
 None
 0.46A 2ql8A-1qu9A:
undetectable
2ql8B-1qu9A:
undetectable		 2ql8A-1qu9A:
25.00
2ql8B-1qu9A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		5 / 7 VAL A  61
VAL A  57
LEU A  54
SER A  53
VAL A  76
 None
 1.44A 3hs6B-1qu9A:
undetectable		 3hs6B-1qu9A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		5 / 9 ILE A  71
VAL A  61
THR A  29
ILE A  28
ILE A  27
 None
 1.01A 3p4wB-1qu9A:
undetectable		 3p4wB-1qu9A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		5 / 10 ILE A  71
VAL A  61
THR A  29
ILE A  28
ILE A  27
 None
 1.02A 3p4wD-1qu9A:
undetectable		 3p4wD-1qu9A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		5 / 8 PRO A  43
VAL A  42
PRO A 114
GLN A  32
ILE A 119
 None
 1.46A 4iilA-1qu9A:
undetectable		 4iilA-1qu9A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		5 / 12 LEU A  66
ALA A 125
ASN A  25
ILE A   5
ALA A  64
 None
 1.07A 5nm5B-1qu9A:
undetectable		 5nm5B-1qu9A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		5 / 9 VAL A  46
ALA A  85
PHE A  84
VAL A  78
ILE A 119
 None
None
CSP  A 107 ( 3.5A)
None
None
 1.13A 5om2A-1qu9A:
undetectable
5om2B-1qu9A:
undetectable		 5om2A-1qu9A:
17.83
5om2B-1qu9A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1qu9 YJGF PROTEIN
(Escherichia
coli) 		4 / 8 GLN A  32
THR A  29
PHE A  94
TYR A  91
 None
 0.86A 6eqpA-1qu9A:
undetectable		 6eqpA-1qu9A:
18.70