SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 213
ILE A 192
LEU A  84
ASP A 208
THR A 146
 None
 1.11A 1jg3A-1qupA:
undetectable		 1jg3A-1qupA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 213
ILE A 192
LEU A  84
ASP A 208
THR A 146
 None
 1.09A 1jg3B-1qupA:
undetectable		 1jg3B-1qupA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A  48
SER A  50
LEU A  61
THR A  56
 None
 1.08A 2f78A-1qupA:
undetectable		 2f78A-1qupA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A  48
SER A  50
LEU A  61
THR A  56
 None
 1.11A 2f78B-1qupA:
undetectable		 2f78B-1qupA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 12 ALA A  80
THR A 182
ALA A 178
ILE A  70
PHE A 153
 None
 1.15A 2nyrA-1qupA:
undetectable		 2nyrA-1qupA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 133
THR A 114
ALA A 178
LEU A 176
 None
 0.76A 5og9A-1qupA:
0.0		 5og9A-1qupA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 7 GLY A 102
LEU A 115
ILE A 157
GLY A 172
ILE A  58
 None
 1.15A 5vkqA-1qupA:
undetectable
5vkqB-1qupA:
undetectable		 5vkqA-1qupA:
11.13
5vkqB-1qupA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 8 GLY A 102
LEU A 115
ILE A 157
GLY A 172
ILE A  58
 None
 1.12A 5vkqB-1qupA:
undetectable
5vkqC-1qupA:
undetectable		 5vkqB-1qupA:
11.13
5vkqC-1qupA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 129
GLN A  88
VAL A 206
ALA A 126
 None
 1.20A 6djzB-1qupA:
undetectable		 6djzB-1qupA:
19.03