SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1quq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	1quq	PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT) (Homo sapiens)	4 / 7	MET B 16 ILE B 106 ARG B 11 VAL B 28	None	1.42A	4f4dA-1quqB: undetectable	4f4dA-1quqB: 15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	1quq	PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT) (Homo sapiens)	4 / 6	MET B 16 ILE B 106 ARG B 11 VAL B 28	None	1.40A	4mk4B-1quqB: undetectable	4mk4B-1quqB: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_A_BRLA501_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1quq	PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT) (Homo sapiens)	4 / 5	GLY B 71 LEU B 17 ILE B 53 LEU B 115	None	0.77A	4o8fA-1quqB: undetectable	4o8fA-1quqB: 19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECN_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1quq	PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT) (Homo sapiens)	4 / 8	ILE B 53 ALA B 77 THR B 78 VAL B 73	None	0.88A	5ecnD-1quqB: undetectable	5ecnD-1quqB: 12.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4F4D_A_CHDA505_0","FERROCHELATASE, MITOCHONDRIAL","1quq","PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT)","Homo sapiens",4,"MET B  16;ILE B 106;ARG B  11;VAL B  28","None","1.42A","4f4dA-1quqB:undetectable","4f4dA-1quqB:15.01"],["4MK4_B_CHDB502_0","FERROCHELATASE, MITOCHONDRIAL","1quq","PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT)","Homo sapiens",4,"MET B  16;ILE B 106;ARG B  11;VAL B  28","None","1.40A","4mk4B-1quqB:undetectable","4mk4B-1quqB:15.30"],["4O8F_A_BRLA501_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1quq","PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT)","Homo sapiens",4,"GLY B  71;LEU B  17;ILE B  53;LEU B 115","None","0.77A","4o8fA-1quqB:undetectable","4o8fA-1quqB:19.16"],["5ECN_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1quq","PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT)","Homo sapiens",4,"ILE B  53;ALA B  77;THR B  78;VAL B  73","None","0.88A","5ecnD-1quqB:undetectable","5ecnD-1quqB:12.13"]]